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Molecular Biology

D-Index
43
Citations
7893
World Ranking
2972
National Ranking
1413

Overview

Jane A. Skok is a researcher affiliated with New York University in the United States. Their work is primarily situated in the broad field of Biochemistry, Genetics and Molecular Biology, with significant contributions in Molecular Biology, Immunology, Oncology, Genetics, and Plant Science.

The research topics covered by Skok include:

  • Genomics and Chromatin Dynamics
  • Epigenetics and DNA Methylation
  • CRISPR and Genetic Engineering
  • RNA Research and Splicing
  • RNA and protein synthesis mechanisms
  • DNA Repair Mechanisms
  • RNA modifications and cancer

Jane A. Skok has contributed to several scientific journals and publication venues, notably:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • Current Opinion in Genetics & Development
  • Nature Genetics
  • Genome Biology

Recent notable peer-reviewed papers by Skok include:

  • "DNA methylation disruption reshapes the hematopoietic differentiation landscape," 2020, published in Nature Genetics
  • "Cell-type-specific prediction of 3D chromatin organization enables high-throughput in silico genetic screening," 2023, published in Nature Biotechnology
  • "CRISPR and biochemical screens identify MAZ as a cofactor in CTCF-mediated insulation at Hox clusters," 2022, published in Nature Genetics
  • "CTCF and CTCFL in cancer," 2020, published in Current Opinion in Genetics & Development
  • "Defining the relative and combined contribution of CTCF and CTCFL to genomic regulation," 2020, published in Genome Biology

Their frequent collaborators include:

  • Catherine Do
  • Aristotelis Tsirigos
  • Giulia Cova
  • Theodore Sakellaropoulos
  • Priscillia Lhoumaud

Best Publications

  • Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development.

    Steven T. Kosak;Jane A. Skok;Kay L. Medina;Roy Riblet

  • CTCF establishes discrete functional chromatin domains at the Hox clusters during differentiation

    Varun Narendra;Varun Narendra;Pedro P. Rocha;Disi An;Ramya Raviram

  • Pax5 induces V-to-DJ rearrangements and locus contraction of the immunoglobulin heavy-chain gene

    Martin Fuxa;Jane Skok;Abdallah Souabni;Giorgia Salvagiotto

  • Locus 'decontraction' and centromeric recruitment contribute to allelic exclusion of the immunoglobulin heavy-chain gene

    Esther Roldán;Martin Fuxa;Winnie Chong;Dolores Martinez

  • Yin Yang 1 is a critical regulator of B-cell development

    Huifei Liu;Marc Schmidt-Supprian;Yujiang Shi;Elias Hobeika

  • Capturing the Onset of PRC2-Mediated Repressive Domain Formation.

    Ozgur Oksuz;Varun Narendra;Chul Hwan Lee;Nicolas Descostes

  • Nonequivalent nuclear location of immunoglobulin alleles in B lymphocytes.

    Jane A. Skok;Karen E. Brown;Veronique Azuara;Marie-Laure Caparros

  • RNA Interactions Are Essential for CTCF-Mediated Genome Organization

    Ricardo Saldaña-Meyer;Javier Rodriguez-Hernaez;Thelma Escobar;Mayilaadumveettil Nishana

  • Regulation of immunoglobulin light-chain recombination by the transcription factor IRF-4 and the attenuation of interleukin-7 signaling

    Kristen Johnson;Tamar Hashimshony;Catherine M. Sawai;Catherine M. Sawai;Jagan M.R. Pongubala;Jagan M.R. Pongubala

  • DNA methylation disruption reshapes the hematopoietic differentiation landscape

    Franco Izzo;Stanley C. Lee;Stanley C. Lee;Asaf Poran;Ronan Chaligne

  • Epigenetic ontogeny of the Igk locus during B cell development

    Maya Goldmit;Yanhong Ji;Jane Skok;Esther Roldan

  • Reversible contraction by looping of the Tcra and Tcrb loci in rearranging thymocytes.

    Jane A Skok;Jane A Skok;Ramiro Gisler;Maria Novatchkova;Deborah Farmer

  • Cohesin loss alters adult hematopoietic stem cell homeostasis, leading to myeloproliferative neoplasms.

    Jasper Mullenders;Beatriz Aranda-Orgilles;Priscillia Lhoumaud;Matthew Keller

  • RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci

    Susannah L Hewitt;Bu Yin;Yanhong Ji;Julie Chaumeil

  • CRISPR-dCas9 and sgRNA scaffolds enable dual-colour live imaging of satellite sequences and repeat-enriched individual loci

    Yi Fu;Pedro P. Rocha;Vincent M. Luo;Ramya Raviram

  • Dendritic Cell-Derived IL-12 Promotes B Cell Induction of Th2 Differentiation: A Feedback Regulation of Th1 Development

    Jane Skok;Johanne Poudrier;David Gray

  • Association between the Igk and Igh immunoglobulin loci mediated by the 3′ Igk enhancer induces 'decontraction' of the Igh locus in pre–B cells

    Susannah L. Hewitt;Deborah Farmer;Katarzyna Marszalek;Emily Cadera

  • MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis

    Beatriz Aranda-Orgilles;Ricardo Saldaña-Meyer;Eric Wang;Eirini Trompouki

  • The RAG2 C terminus suppresses genomic instability and lymphomagenesis

    Ludovic Deriano;Julie Chaumeil;Marc Coussens;Asha Multani

  • Low-Grade Astrocytoma Mutations in IDH1, P53, and ATRX Cooperate to Block Differentiation of Human Neural Stem Cells via Repression of SOX2.

    Aram S. Modrek;Danielle Golub;Themasap Khan;Devin Bready

Frequent Co-Authors

Richard Bonneau
Richard Bonneau New York University
Aristotelis Tsirigos
Aristotelis Tsirigos New York University
Danny Reinberg
Danny Reinberg University of Miami
Yuval Kluger
Yuval Kluger Yale University
Iannis Aifantis
Iannis Aifantis New York University
Meinrad Busslinger
Meinrad Busslinger Research Institute of Molecular Pathology
Klaus Rajewsky
Klaus Rajewsky Max Delbrück Center for Molecular Medicine
Ferhat Ay
Ferhat Ay La Jolla Institute For Allergy & Immunology
Benoit G. Bruneau
Benoit G. Bruneau Gladstone Institutes
David Roth
David Roth University of Miami

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