Reinhard Kofler

Overview

Best Publications

• The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species.

  Astrid A. Ruefli;Michael J. Ausserlechner;David Bernhard;Vivien R. Sutton

  690
  Citations

• Glucocorticoid-induced apoptosis and glucocorticoid resistance: molecular mechanisms and clinical relevance.

  S Schmidt;J Rainer;C Ploner;E Presul

  449
  Citations

• Bcl-2 and Bcl-XL Antagonize the Mitochondrial Dysfunction Preceding Nuclear Apoptosis Induced by Chemotherapeutic Agents

  Didier Decaudin;Stephan Geley;Tamara Hirsch;Maria Castedo

  419
  Citations

• Noxa: at the tip of the balance between life and death.

  C Ploner;R Kofler;A Villunger

  318
  Citations

• Drug-induced Apoptosis Is Associated with Enhanced Fas (Apo-1/CD95) Ligand Expression but Occurs Independently of Fas (Apo-1/CD95) Signaling in Human T-Acute Lymphatic Leukemia Cells

  Andreas Villunger;Alexander Egle;Marion Kos;Bernd L. Hartmann

  270
  Citations

• CLP1 links tRNA metabolism to progressive motor-neuron loss

  Toshikatsu Hanada;Stefan Weitzer;Barbara Mair;Christian Bernreuther

  262
  Citations

• Resveratrol, a tumor-suppressive compound from grapes, induces apoptosis via a novel mitochondrial pathway controlled by Bcl-2.

  Inge Tinhofer;David Bernhard;Monika Senfter;Gabriele Anether

  233
  Citations

• A Molecular Function Map of Ewing's Sarcoma

  Maximilian Kauer;Jozef Ban;Reinhard Kofler;Bob Walker

  230
  Citations

• Resveratrol causes arrest in the S-phase prior to Fas-independent apoptosis in CEM-C7H2 acute leukemia cells.

  D Bernhard;I Tinhofer;M Tonko;H Hübl

  227
  Citations

• The thiol crosslinking agent diamide overcomes the apoptosis-inhibitory effect of Bcl-2 by enforcing mitochondrial permeability transition.

  Naoufal Zamzami;Isabel Marzo;Santos A Susin;Catherine Brenner

  203
  Citations

• Apoptosis induced by the histone deacetylase inhibitor sodium butyrate in human leukemic lymphoblasts

  David Bernhard;Michael J. Ausserlechner;Martin Tonko;Markus Löffler

  196
  Citations

• Identification of glucocorticoid-response genes in children with acute lymphoblastic leukemia

  Stefan Schmidt;Stefan Schmidt;Johannes Rainer;Johannes Rainer;Stefan Riml;Stefan Riml;Christian Ploner;Christian Ploner

  188
  Citations

• Enhanced MTT-reducing activity under growth inhibition by resveratrol in CEM-C7H2 lymphocytic leukemia cells.

  David Bernhard;Wolfgang Schwaiger;Roman Crazzolara;Inge Tinhofer

  179
  Citations

• Changes of mitochondrial respiration, mitochondrial content and cell size after induction of apoptosis in leukemia cells.

  Kathrin Renner;Albert Amberger;Günther Konwalinka;Reinhard Kofler

  176
  Citations

• CYP11B1 Mutations Causing Non-Classic Adrenal Hyperplasia due to 11β-Hydroxylase Deficiency

  Karin Joehrer;Stephan Geley;Elisabeth M.C. Strasser-Wozak;Ricardo Azziz

  170
  Citations

• The BCL2 rheostat in glucocorticoid-induced apoptosis of acute lymphoblastic leukemia.

  C Ploner;J Rainer;H Niederegger;M Eduardoff

  169
  Citations

• Cancer cell line identification by short tandem repeat profiling: power and limitations

  Walther Parson;Romana Kirchebner;Roswitha Mühlmann;Kathrin Renner

  165
  Citations

• Constitutive expression of Fas (Apo-1/CD95) ligand on multiple myeloma cells: a potential mechanism of tumor-induced suppression of immune surveillance.

  Andreas Villunger;Alexander Egle;Ingrid Marschitz;Marion Kos

  158
  Citations

• CYP11B1 mutations causing congenital adrenal hyperplasia due to 11 beta-hydroxylase deficiency.

  Stephan Geley;Klaus Kapelari;Karin Jöhrer;Michael Peter

  151
  Citations

• The Role of Somatic Mutation in the Generation of the Protective Humoral Immune Response against Vesicular Stomatitis Virus

  Ulrich Kalinke;Etienne M. Bucher;Bettina Ernst;Annette Oxenius

  151
  Citations