His primary scientific interests are in Apoptosis, Programmed cell death, Cancer research, Molecular biology and Gene expression profiling. His study connects Mitochondrion and Apoptosis. The concepts of his Cancer research study are interwoven with issues in Fas receptor and Leukemia.
His work carried out in the field of Molecular biology brings together such families of science as Cell, Denervation, Cytochrome c, Cell biology and Resveratrol. His Gene expression profiling research includes elements of Transcription factor, Acute lymphocytic leukemia and Lymphoblast. His study looks at the intersection of Lymphoblast and topics like DNA microarray with Immunology.
His primary areas of investigation include Apoptosis, Molecular biology, Cancer research, Programmed cell death and Internal medicine. His Apoptosis research is multidisciplinary, incorporating elements of Cell culture and Leukemia, Immunology, Glucocorticoid. His studies in Molecular biology integrate themes in fields like Mutation, Genetics, Gene, Exon and Monoclonal antibody.
Reinhard Kofler interconnects Cell growth, Gene expression profiling, Fas receptor, Cell cycle and Regulation of gene expression in the investigation of issues within Cancer research. His studies deal with areas such as Receptor and DNA damage as well as Programmed cell death. His Internal medicine research includes themes of Endocrinology, Antiserum and In vivo.
His primary areas of study are Cell biology, Gene, Cancer research, Programmed cell death and Regulation of gene expression. His research integrates issues of Cell culture, Transcription factor and Molecular biology in his study of Cell biology. His Cancer research course of study focuses on Cyclin-dependent kinase 2 and Kinase activity and Janus kinase 2.
His biological study spans a wide range of topics, including Cell cycle checkpoint and Gene expression profiling. Cell cycle checkpoint is a subfield of Apoptosis that Reinhard Kofler investigates. His Gene expression profiling study combines topics from a wide range of disciplines, such as Childhood Acute Lymphoblastic Leukemia and Immunology.
His main research concerns Cell biology, Cancer research, ETV6, Molecular biology and RNA. His Cell biology study integrates concerns from other disciplines, such as Peroxisome, Pathology, Downregulation and upregulation and Transcription factor. His Cancer research study incorporates themes from Janus kinase 2, Janus kinase, MAP2K7, Cyclin-dependent kinase 2 and Kinase activity.
ETV6 combines with fields such as Genetics, Fusion gene, Cell activation, PI3K/AKT/mTOR pathway and Gene in his research. Reinhard Kofler performs multidisciplinary study in Molecular biology and TRNA processing in his work. His work carried out in the field of RNA brings together such families of science as Cell culture, Gene knockdown, Gene expression and Denervation.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species.
Astrid A. Ruefli;Michael J. Ausserlechner;David Bernhard;Vivien R. Sutton.
Proceedings of the National Academy of Sciences of the United States of America (2001)
Bcl-2 and Bcl-XL Antagonize the Mitochondrial Dysfunction Preceding Nuclear Apoptosis Induced by Chemotherapeutic Agents
Didier Decaudin;Stephan Geley;Tamara Hirsch;Maria Castedo.
Cancer Research (1997)
Glucocorticoid-induced apoptosis and glucocorticoid resistance: molecular mechanisms and clinical relevance.
S Schmidt;J Rainer;C Ploner;E Presul.
Cell Death & Differentiation (2004)
Drug-induced Apoptosis Is Associated with Enhanced Fas (Apo-1/CD95) Ligand Expression but Occurs Independently of Fas (Apo-1/CD95) Signaling in Human T-Acute Lymphatic Leukemia Cells
Andreas Villunger;Alexander Egle;Marion Kos;Bernd L. Hartmann.
Cancer Research (1997)
Noxa: at the tip of the balance between life and death
C Ploner;R Kofler;A Villunger.
Resveratrol, a tumor-suppressive compound from grapes, induces apoptosis via a novel mitochondrial pathway controlled by Bcl-2.
Inge Tinhofer;David Bernhard;Monika Senfter;Gabriele Anether.
The FASEB Journal (2001)
Resveratrol causes arrest in the S-phase prior to Fas-independent apoptosis in CEM-C7H2 acute leukemia cells.
D Bernhard;I Tinhofer;M Tonko;H Hübl.
Cell Death & Differentiation (2000)
Constitutive expression of Fas (Apo-1/CD95) ligand on multiple myeloma cells: a potential mechanism of tumor-induced suppression of immune surveillance.
Andreas Villunger;Alexander Egle;Ingrid Marschitz;Marion Kos.
A Molecular Function Map of Ewing's Sarcoma
Maximilian Kauer;Jozef Ban;Reinhard Kofler;Bob Walker.
PLOS ONE (2009)
Apoptosis induced by the histone deacetylase inhibitor sodium butyrate in human leukemic lymphoblasts
David Bernhard;Michael J. Ausserlechner;Martin Tonko;Markus Löffler.
The FASEB Journal (1999)
If you think any of the details on this page are incorrect, let us know.
We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below: