What is he best known for?
The fields of study he is best known for:
His primary scientific interests are in Apoptosis, Programmed cell death, Cancer research, Molecular biology and Gene expression profiling.
His study connects Mitochondrion and Apoptosis.
The concepts of his Cancer research study are interwoven with issues in Fas receptor and Leukemia.
His work carried out in the field of Molecular biology brings together such families of science as Cell, Denervation, Cytochrome c, Cell biology and Resveratrol.
His Gene expression profiling research includes elements of Transcription factor, Acute lymphocytic leukemia and Lymphoblast.
His study looks at the intersection of Lymphoblast and topics like DNA microarray with Immunology.
His most cited work include:
- The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species. (421 citations)
- Glucocorticoid-induced apoptosis and glucocorticoid resistance: molecular mechanisms and clinical relevance. (280 citations)
- Bcl-2 and Bcl-XL Antagonize the Mitochondrial Dysfunction Preceding Nuclear Apoptosis Induced by Chemotherapeutic Agents (280 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of investigation include Apoptosis, Molecular biology, Cancer research, Programmed cell death and Internal medicine.
His Apoptosis research is multidisciplinary, incorporating elements of Cell culture and Leukemia, Immunology, Glucocorticoid.
His studies in Molecular biology integrate themes in fields like Mutation, Genetics, Gene, Exon and Monoclonal antibody.
Reinhard Kofler interconnects Cell growth, Gene expression profiling, Fas receptor, Cell cycle and Regulation of gene expression in the investigation of issues within Cancer research.
His studies deal with areas such as Receptor and DNA damage as well as Programmed cell death.
His Internal medicine research includes themes of Endocrinology, Antiserum and In vivo.
He most often published in these fields:
- Apoptosis (34.68%)
- Molecular biology (34.68%)
- Cancer research (33.06%)
What were the highlights of his more recent work (between 2010-2020)?
- Cell biology (12.10%)
- Gene (22.58%)
- Cancer research (33.06%)
In recent papers he was focusing on the following fields of study:
His primary areas of study are Cell biology, Gene, Cancer research, Programmed cell death and Regulation of gene expression.
His research integrates issues of Cell culture, Transcription factor and Molecular biology in his study of Cell biology.
His Cancer research course of study focuses on Cyclin-dependent kinase 2 and Kinase activity and Janus kinase 2.
His biological study spans a wide range of topics, including Cell cycle checkpoint and Gene expression profiling.
Cell cycle checkpoint is a subfield of Apoptosis that Reinhard Kofler investigates.
His Gene expression profiling study combines topics from a wide range of disciplines, such as Childhood Acute Lymphoblastic Leukemia and Immunology.
Between 2010 and 2020, his most popular works were:
- CLP1 links tRNA metabolism to progressive motor-neuron loss (147 citations)
- ETV6/RUNX1-positive relapses evolve from an ancestral clone and frequently acquire deletions of genes implicated in glucocorticoid signaling (70 citations)
- The Leukemia-Specific Fusion Gene ETV6/RUNX1 Perturbs Distinct Key Biological Functions Primarily by Gene Repression (43 citations)
In his most recent research, the most cited papers focused on:
His main research concerns Cell biology, Cancer research, ETV6, Molecular biology and RNA.
His Cell biology study integrates concerns from other disciplines, such as Peroxisome, Pathology, Downregulation and upregulation and Transcription factor.
His Cancer research study incorporates themes from Janus kinase 2, Janus kinase, MAP2K7, Cyclin-dependent kinase 2 and Kinase activity.
ETV6 combines with fields such as Genetics, Fusion gene, Cell activation, PI3K/AKT/mTOR pathway and Gene in his research.
Reinhard Kofler performs multidisciplinary study in Molecular biology and TRNA processing in his work.
His work carried out in the field of RNA brings together such families of science as Cell culture, Gene knockdown, Gene expression and Denervation.
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