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Biology and Biochemistry

D-Index
64
Citations
17229
World Ranking
9541
National Ranking
83

Overview

Erich Gnaiger is affiliated with Innsbruck Medical University in Austria and has a research focus primarily within the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their work extensively covers Molecular Biology, Physiology, Clinical Biochemistry, Cancer Research, and Biomedical Engineering.

The main topics of their research include:

  • Mitochondrial Function and Pathology
  • Adipose Tissue and Metabolism
  • ATP Synthase and ATPases Research
  • Metabolism and Genetic Disorders
  • Cancer, Hypoxia, and Metabolism
  • Metabolomics and Mass Spectrometry Studies
  • Cardiovascular and exercise physiology

They have contributed to multiple publications, with notable recent papers including:

  • OXPHOS remodeling in high-grade prostate cancer involves mtDNA mutations and increased succinate oxidation, 2020, Nature Communications
  • Mitochondrial Pathways and Respiratory Control, 2020, Oroboros Instruments
  • Skeletal Muscle Mitochondrial Respiration and Exercise Intolerance in Patients With Heart Failure With Preserved Ejection Fraction, 2023, JAMA Cardiology
  • Complex II ambiguities-FADH2 in the electron transfer system, 2023, Journal of Biological Chemistry
  • Fatty acyl availability modulates cardiolipin composition and alters mitochondrial function in HeLa cells, 2021, Journal of Lipid Research

Erich Gnaiger frequently collaborates with several co-authors, including:

  • Tímea Komlódi
  • Carolina Doerrier
  • Luiza H.D. Cardoso
  • Luiz F. Garcia-Souza
  • Christos Chinopoulos

Their work has been published in various venues, with a significant number of publications appearing in:

  • Biochimica et Biophysica Acta (BBA) - Bioenergetics
  • Zenodo (CERN European Organization for Nuclear Research)
  • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  • Oroboros Instruments
  • JAMA Cardiology

Best Publications

  • High-resolution respirometry: OXPHOS protocols for human cells and permeabilized fibers from small biopsies of human muscle.

    Dominik Pesta;Erich Gnaiger

  • Calculation of energetic and biochemical equivalents of respiratory oxygen consumption

    E. Gnaiger

  • Thiazolidinediones, like metformin, inhibit respiratory complex I: a common mechanism contributing to their antidiabetic actions?

    Barbara Brunmair;Katrin Staniek;Florian Gras;Nicole Scharf

  • Patients with type 2 diabetes have normal mitochondrial function in skeletal muscle

    R. Boushel;E. Gnaiger;P. Schjerling;M. Skovbro

  • Capacity of oxidative phosphorylation in human skeletal muscle: new perspectives of mitochondrial physiology.

    Erich Gnaiger

  • Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism

    Julián Aragonés;Martin Schneider;Martin Schneider;Martin Schneider;Katie Van Geyte;Katie Van Geyte;Peter Fraisl;Peter Fraisl

  • Proximate biochemical composition and caloric content calculated from elemental CHN analysis: a stoichiometric concept

    E. Gnaiger;G. Bitterlich

  • Mitochondrial oxygen affinity, respiratory flux control and excess capacity of cytochrome c oxidase

    E Gnaiger;B Lassnig;A Kuznetsov;G Rieger

  • Polarographic Oxygen Sensors

    Erich Gnaiger;Hellmuth Forstner

  • Control of mitochondrial and cellular respiration by oxygen.

    Erich Gnaiger;Rosmarie Steinlechner-Maran;Gabriela Méndez;Thomas Eberl

  • Bioenergetics at low oxygen: dependence of respiration and phosphorylation on oxygen and adenosine diphosphate supply

    Erich Gnaiger

  • High phosphorylation efficiency and depression of uncoupled respiration in mitochondria under hypoxia

    Erich Gnaiger;Gabriela Méndez;Steven C. Hand

  • Iron-dependent changes in cellular energy metabolism: influence on citric acid cycle and oxidative phosphorylation

    Horst Oexle;Erich Gnaiger;Günter Weiss

  • Senescence-associated changes in respiration and oxidative phosphorylation in primary human fibroblasts.

    Eveline Hutter;Kathrin Renner;Gerald Pfister;Petra Stöckl

  • Heat dissipation and energetic efficiency in animal anoxibiosis: Economy contra power

    Erich Gnaiger

  • Mitochondria in the Cold

    Erich Gnaiger;Andrej V. Kuznetsov;Stefan Schneeberger;RÜdiger Seiler

  • Anaerobic metabolism in aerobic mammalian cells: information from the ratio of calorimetric heat flux and respirometric oxygen flux

    Erich Gnaiger;Richard B. Kemp

  • High-Resolution Respirometry for Simultaneous Measurement of Oxygen and Hydrogen Peroxide Fluxes in Permeabilized Cells, Tissue Homogenate and Isolated Mitochondria

    Marina Makrecka-Kuka;Gerhard Krumschnabel;Erich Gnaiger

  • Mitochondrial defects and heterogeneous cytochrome c release after cardiac cold ischemia and reperfusion.

    Andrey V. Kuznetsov;Stefan Schneeberger;Rüdiger Seiler;Gerald Brandacher

  • Metabolic basis to Sherpa altitude adaptation.

    James A. Horscroft;Aleksandra O. Kotwica;Verena Laner;James A. West

Frequent Co-Authors

Andrey V. Kuznetsov
Andrey V. Kuznetsov Innsbruck Medical University
Martin Burtscher
Martin Burtscher University of Innsbruck
Bengt Saltin
Bengt Saltin University of Copenhagen
Pidder Jansen-Dürr
Pidder Jansen-Dürr University of Innsbruck
Jose A. L. Calbet
Jose A. L. Calbet University of Las Palmas de Gran Canaria
Michael P. W. Grocott
Michael P. W. Grocott University of Southampton
Heinz Redl
Heinz Redl Ludwig Boltzmann Institute for Experimental and Clinical Traumatology
Eskil Elmér
Eskil Elmér Lund University
Martin Feelisch
Martin Feelisch University of Southampton
Max Gassmann
Max Gassmann University of Zurich

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