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Medicine

D-Index
122
Citations
67548
World Ranking
3426
National Ranking
1888

Research.com Recognitions

  • 2010 - Rhoda and Bernard Sarnat International Prize in Mental Health, National Academy of Medicine
  • 1991 - Member of the National Academy of Medicine (NAM)

Overview

Charles P. O'Brien is affiliated with the University of Pennsylvania in the United States. Their research spans the fields of neuroscience and medicine, with a particular focus on cellular and molecular neuroscience as well as cognitive neuroscience. Additional subfields include experimental and cognitive psychology, physiology, and cardiology and cardiovascular medicine.

The main topics of Charles P. O'Brien's work include:

  • Neurotransmitter receptor influence on behavior
  • Anxiety, depression, psychometrics, treatment, cognitive processes
  • Functional brain connectivity studies
  • Physical activity and health
  • Neural and behavioral psychology studies
  • Cannabis and cannabinoid research
  • Forensic toxicology and drug analysis

Several journals and publication venues have featured their research, including:

  • Alzheimer's & Dementia
  • Addiction Biology
  • NeuroImage Clinical
  • Cold Spring Harbor Perspectives in Medicine
  • CIN Computers Informatics Nursing

Frequent collaborators include Anna Rose Childress, Daniel D. Langleben, Lenora Smith, Zhenhao Shi, and Kanchana Jagannathan. These researchers have coauthored multiple papers with Charles P. O'Brien.

Notable recent papers authored or coauthored by Charles P. O'Brien are:

  • The role of withdrawal in mesocorticolimbic drug cue reactivity in opioid use disorder, 2020, Addiction Biology
  • Multivariate pattern analysis links drug use severity to distributed cortical hypoactivity during emotional inhibitory control in opioid use disorder, 2021, NeuroImage Clinical
  • The Persistent Challenge of Developing Addiction Pharmacotherapies, 2020, Cold Spring Harbor Perspectives in Medicine
  • The Mobile Physical Activity and Cognitive Training App for Older Adults, 2020, CIN Computers Informatics Nursing
  • Effects of current smoking severity on brain gray matter volume in opioid use disorder - a voxel-based morphometry study, 2023, The American Journal of Drug and Alcohol Abuse

Charles P. O'Brien's contributions have been recognized with awards such as the Rhoda and Bernard Sarnat International Prize in Mental Health from the National Academy of Medicine in 2010. They have also been a member of the National Academy of Medicine since 1991.

Best Publications

  • An improved diagnostic evaluation instrument for substance abuse patients. The Addiction Severity Index.

    A T McLellan;L Luborsky;G E Woody;C P O'Brien

  • Drug Dependence, a Chronic Medical Illness: Implications for Treatment, Insurance, and Outcomes Evaluation

    A. Thomas McLellan;David C. Lewis;Herbert D. Kleber

  • Naltrexone in the treatment of alcohol dependence

    Joseph R. Volpicelli;Arthur I. Alterman;Motoi Hayashida;Charles P. O'Brien

  • Limbic Activation During Cue-Induced Cocaine Craving

    Anna Rose Childress;P. David Mozley;William McElgin;Josh Fitzgerald

  • DSM-5 Criteria for Substance Use Disorders: Recommendations and Rationale

    Deborah S. Hasin;Charles P. O’Brien;Marc Auriacombe;Guilherme Borges

  • The Effects of Psychosocial Services in Substance Abuse Treatment

    A T McLellan;I O Arndt;D S Metzger;G E Woody

  • Predicting Response to Alcohol and Drug Abuse Treatments: Role of Psychiatric Severity

    A T McLellan;L Luborsky;G E Woody;C P O'Brien

  • An international consensus for assessing internet gaming disorder using the new DSM-5 approach

    Nancy M. Petry;Florian Rehbein;Douglas A. Gentile;Jeroen S. Lemmens

  • Therapist Success and Its Determinants

    Lester Luborsky;A. Thomas McLellan;George E. Woody;Charles P. O'Brien

  • Conditioning factors in drug abuse: can they explain compulsion?:

    Charles P. O'Brien;Anna Rose Childress;Ronald Ehrman;Steven J. Robbins

  • Decreased gray matter concentration in the insular, orbitofrontal, cingulate, and temporal cortices of cocaine patients

    Teresa R Franklin;Paul D Acton;Joseph A Maldjian;Jason D Gray

  • A Functional Polymorphism of the μ -Opioid Receptor Gene is Associated with Naltrexone Response in Alcohol-Dependent Patients

    David W Oslin;David W Oslin;Wade Berrettini;Henry R Kranzler;Helen Pettinati

  • Myths about the treatment of addiction

    CharlesP. O'Brien;A. Thomas McLellan

  • Classical conditioning in drug-dependent humans.

    Charles P. O'brien;Anna Rose Childress;A. Thomas McLELLAN;Ronald Ehrman

  • Human immunodeficiency virus seroconversion among intravenous drug users in- and out-of-treatment: an 18-month prospective follow-up

    D S Metzger;G E Woody;A T McLellan;C P O'Brien

  • Internet gaming disorder and the DSM‐5

    Nancy M. Petry;Charles P. O'Brien

  • Conditioned responses to cocaine-related stimuli in cocaine abuse patients.

    Ronald N. Ehrman;Steven J. Robbins;Anna Rose Childress;Charles P. O'Brien

  • Naltrexone and Alcohol Dependence: Role of Subject Compliance

    Joseph R. Volpicelli;Karen C. Rhines;Jared S. Rhines;Laura A. Volpicelli

  • Benzodiazepine Use, Abuse, and Dependence

    Charles P O'brien

  • Similarity of outcome predictors across opiate, cocaine, and alcohol treatments: Role of treatment services.

    A. Thomas McLellan;Arthur I. Alterman;David S. Metzger;Grant R. Grissom

Frequent Co-Authors

Anna Rose Childress
Anna Rose Childress University of Pennsylvania
George E. Woody
George E. Woody University of Pennsylvania
David W. Oslin
David W. Oslin University of Pennsylvania
Charles A. Dackis
Charles A. Dackis University of Pennsylvania
Arthur I. Alterman
Arthur I. Alterman University of Pennsylvania
A. Thomas McLellan
A. Thomas McLellan University of Pennsylvania
Kevin G. Lynch
Kevin G. Lynch University of Pennsylvania
Wade H. Berrettini
Wade H. Berrettini University of Pennsylvania
Edward V. Nunes
Edward V. Nunes Columbia University
David S. Metzger
David S. Metzger University of Pennsylvania

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