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D-Index
128
Citations
59776
World Ranking
2718
National Ranking
1520

Overview

Henry R. Kranzler is affiliated with the University of Pennsylvania in the United States. Their research focuses primarily on medicine and biochemistry, genetics, and molecular biology. They have made significant contributions in several related subfields, including epidemiology, genetics, pathology and forensic medicine, molecular biology, and cellular and molecular neuroscience.

Their work encompasses a wide range of topics. Major areas of study include substance abuse treatment and outcomes, genetic associations and epidemiology, alcohol consumption and health effects, neurotransmitter receptor influence on behavior, opioid use disorder treatment, epigenetics and DNA methylation, and cannabis and cannabinoid research.

Henry R. Kranzler has co-authored extensively with several frequent collaborators. Notable colleagues include Joel Gelernter, Rachel L. Kember, Hang Zhou, Emily E. Hartwell, and Renato Polimanti.

The venues where this scientist's research is often published include bioRxiv (Cold Spring Harbor Laboratory), European Neuropsychopharmacology, Alcohol Clinical and Experimental Research, Drug and Alcohol Dependence, and Biological Psychiatry.

Selected recent papers by Henry R. Kranzler include:

  • Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits (2020, Nature Neuroscience)
  • A large-scale genome-wide association study meta-analysis of cannabis use disorder (2020, The Lancet Psychiatry)
  • Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction (2021, Nature Neuroscience)
  • Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program (2024, Science)
  • Associations between alcohol consumption and gray and white matter volumes in the UK Biobank (2022, Nature Communications)

Best Publications

  • Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

    Ditte Demontis;Ditte Demontis;Raymond K Walters;Raymond K Walters;Joanna Martin;Joanna Martin;Joanna Martin;Manuel Mattheisen

  • The Alcohol Use Disorders Identification Test (AUDIT): validation of a screening instrument for use in medical settings.

    Michael J. Bohn;Thomas F. Babor;Henry R. Kranzler

  • Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

    Niamh Mullins;Andreas J. Forstner;Andreas J. Forstner;Andreas J. Forstner;Kevin S. O'Connell;Kevin S. O'Connell;Brandon Coombes

  • Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

    Phil H. Lee;Verneri Anttila;Hyejung Won;Yen-Chen A. Feng

  • Efficacy and Tolerability of Long-Acting Injectable Naltrexone for Alcohol Dependence: A Randomized Controlled Trial

    James C. Garbutt;Henry R. Kranzler;Stephanie S. O’Malley;David R. Gastfriend;David R. Gastfriend

  • A Functional Polymorphism of the μ -Opioid Receptor Gene is Associated with Naltrexone Response in Alcohol-Dependent Patients

    David W Oslin;David W Oslin;Wade Berrettini;Henry R Kranzler;Helen Pettinati

  • Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

    Raymond K. Walters;Raymond K. Walters;Renato Polimanti;Emma C. Johnson;Jeanette N. McClintick

  • Opioid-, cannabis- and alcohol-dependent women show more rapid progression to substance abuse treatment

    Carlos A Hernandez-Avila;Bruce J Rounsaville;Henry R Kranzler

  • International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci

    Caroline M. Nievergelt;Caroline M. Nievergelt;Adam X. Maihofer;Adam X. Maihofer;Torsten Klengel;Torsten Klengel;Elizabeth G. Atkinson;Elizabeth G. Atkinson

  • Topiramate for Treating Alcohol Dependence: A Randomized Controlled Trial

    Bankole A. Johnson;Norman Rosenthal;Julie A. Capece;Frank Wiegand

  • Diagnosis and Pharmacotherapy of Alcohol Use Disorder: A Review.

    Henry R. Kranzler;Henry R. Kranzler;Michael Soyka

  • Serotonin transporter protein (SLC6A4) allele and haplotype frequencies and linkage disequilibria in African- and European-American and Japanese populations and in alcohol-dependent subjects

    J. Gelernter;Henry Kranzler;Joseph F. Cubells

  • Give them prizes, and they will come: contingency management for treatment of alcohol dependence.

    Nancy M. Petry;Bonnie Martin;Judith L. Cooney;Henry R. Kranzler

  • Alcohol treatment utilization: findings from the National Epidemiologic Survey on Alcohol and Related Conditions.

    Emily Cohen;Richard Feinn;Albert Arias;Henry R. Kranzler

  • Efficacy of naltrexone and acamprosate for alcoholism treatment: a meta-analysis.

    Henry R. Kranzler;Jeffrey Van Kirk

  • Largest GWAS of PTSD (N=20 070) yields genetic overlap with schizophrenia and sex differences in heritability

    L. E. Duncan;A. Ratanatharathorn;A. E. Aiello;L. M. Almli

  • Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations

    Henry R. Kranzler;Henry R. Kranzler;Hang Zhou;Hang Zhou;Rachel L. Kember;Rachel L. Kember;Rachel Vickers Smith;Rachel Vickers Smith

  • A Prospective Cohort Study Investigating Factors Associated With Depression During Medical Internship

    Srijan Sen;Henry R. Kranzler;John H. Krystal;Heather Speller

  • Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci

    J Gelernter;H R Kranzler;R Sherva;L Almasy

  • Genome wide meta-analysis identifies genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders

    Lee Ph;Anttila;Won H

Frequent Co-Authors

Joel Gelernter
Joel Gelernter Yale University
Lindsay A. Farrer
Lindsay A. Farrer Boston University
Hongyu Zhao
Hongyu Zhao Yale University
Raymond F. Anton
Raymond F. Anton Medical University of South Carolina
Howard Tennen
Howard Tennen University of Connecticut
Stephanie S. O'Malley
Stephanie S. O'Malley Yale University
Roger D. Weiss
Roger D. Weiss Harvard University
Karl Mann
Karl Mann Heidelberg University
John H. Krystal
John H. Krystal Yale University
Howard J. Edenberg
Howard J. Edenberg Indiana University

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