World's Best Scientists 2026 revealed!
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Neuroscience
USA
2026

D-Index & Metrics

Neuroscience

D-Index
145
Citations
82479
World Ranking
173
National Ranking
111

Medicine

D-Index
146
Citations
83661
World Ranking
1335
National Ranking
773

Research.com Recognitions

  • 2026 - Research.com Neuroscience in United States Leader Award
  • 2025 - Research.com Neuroscience in United States Leader Award

Overview

David Goldman is affiliated with the National Institutes of Health in the United States and has contributed extensively to the field of medicine, with a particular focus on molecular biology, clinical psychology, epidemiology, cognitive neuroscience, and genetics.

The scientist's work centers on key topics including alcohol consumption and health effects, substance abuse treatment and outcomes, liver disease diagnosis and treatment, COVID-19 and mental health, genetic associations and epidemiology, stress responses and cortisol, and prenatal substance exposure effects.

David Goldman's recent research contributions include the following publications:

  • Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders, 2023, Nature Mental Health
  • Genome-wide Association Study and Meta-analysis on Alcohol-Associated Liver Cirrhosis Identifies Genetic Risk Factors, 2020, Hepatology
  • A genetic risk score and diabetes predict development of alcohol-related cirrhosis in drinkers, 2021, Journal of Hepatology
  • Bile acid-activated macrophages promote biliary epithelial cell proliferation through integrin αvβ6 upregulation following liver injury, 2021, Journal of Clinical Investigation
  • Longitudinal gut microbiome changes in alcohol use disorder are influenced by abstinence and drinking quantity, 2020, Gut Microbes

David Goldman has frequently collaborated with several co-authors throughout their career. These include:

  • Daniel H. Geschwind
  • Joel Gelernter
  • Anissa Abi-Dargham
  • New York
  • Deanna M. Barch

The scientist has published frequently in several venues, with notable numbers of publications in:

  • Biological Psychiatry
  • UNC Libraries
  • Molecular Psychiatry
  • Frontiers in Psychiatry
  • Hepatology

Best Publications

  • The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function

    Michael F. Egan;Masami Kojima;Masami Kojima;Joseph H. Callicott;Terry E. Goldberg

  • Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia.

    Michael F. Egan;Terry E. Goldberg;Bhaskar S. Kolachana;Joseph H. Callicott

  • Serotonin Transporter Genetic Variation and the Response of the Human Amygdala

    Ahmad R. Hariri;Venkata S. Mattay;Alessandro Tessitore;Bhaskar Kolachana

  • Genetic basis for individual variations in pain perception and the development of a chronic pain condition

    Luda Diatchenko;Gary D. Slade;Andrea G. Nackley;Konakporn Bhalang

  • COMT val158met Genotype Affects µ-Opioid Neurotransmitter Responses to a Pain Stressor

    Jon-Kar Zubieta;Mary M. Heitzeg;Yolanda R. Smith;Joshua A. Bueller

  • The genetics of addictions: Uncovering the genes

    David Goldman;Gabor Oroszi;Francesca Ducci

  • Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder.

    Xian-Zhang Hu;Robert H. Lipsky;Guanshan Zhu;Longina A. Akhtar

  • Executive subprocesses in working memory: relationship to catechol-O-methyltransferase Val158Met genotype and schizophrenia.

    Terry E. Goldberg;Michael F. Egan;Tonya Gscheidle;Richard Coppola

  • A Functional Polymorphism in the COMT Gene and Performance on a Test of Prefrontal Cognition

    Anil K Malhotra;Lisa J Kestler;Chiara Mazzanti;John A Bates

  • Genotype Influences In Vivo Dopamine Transporter Availability in Human Striatum

    Andreas Heinz;David Goldman;Douglas W Jones;Roberta Palmour

  • Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

    Raymond K. Walters;Raymond K. Walters;Renato Polimanti;Emma C. Johnson;Jeanette N. McClintick

  • Dating the Origin of the CCR5-Δ32 AIDS-Resistance Allele by the Coalescence of Haplotypes

    J. Claiborne Stephens;David E. Reich;David B. Goldstein;Hyoung Doo Shin

  • GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence

    Irmgard Tegeder;Michael Costigan;Robert S Griffin;Andrea Abele

  • The Alcohol Flushing Response: An Unrecognized Risk Factor for Esophageal Cancer from Alcohol Consumption

    Philip J Brooks;Mary-Anne Enoch;David Goldman;Ting-Kai Li

  • An evaluation of μ-opioid receptor (OPRM1) as a predictor of naltrexone response in the treatment of alcohol dependence: Results from the combined pharmacotherapies and behavioral interventions for alcohol dependence (COMBINE) study

    Raymond F. Anton;Gabor Oroszi;Stephanie O’Malley;David Couper

  • An Expanded Evaluation of the Relationship of Four Alleles to the Level of Response to Alcohol and the Alcoholism Risk

    Xianzhang Hu;Gabor Oroszi;Jeffrey Chun;Tom L. Smith

  • Suicidality and 5-hydroxyindoleacetic acid concentration associated with a tryptophan hydroxylase polymorphism

    David A. Nielsen;David Goldman;Matti Virkkunen;Riitta Tokola

  • The cheetah is depauperate in genetic variation.

    Stephen J. O'Brien;David E. Wildt;David Goldman;Carl R. Merril

  • A relationship between serotonin transporter genotype and in vivo protein expression and alcohol neurotoxicity.

    Andreas Heinz;Douglas W Jones;Chiara Mazzanti;David Goldman

  • Genetic variation in human NPY expression affects stress response and emotion

    Zhifeng Zhou;Guanshan Zhu;Guanshan Zhu;Ahmad R. Hariri;Mary Anne Enoch

  • Disrupted in Schizophrenia 1 (DISC1): Association with Schizophrenia, Schizoaffective Disorder, and Bipolar Disorder

    Colin A. Hodgkinson;David Goldman;Judith Jaeger;Shalini Persaud

Frequent Co-Authors

Matti Virkkunen
Matti Virkkunen University of Helsinki
Markku Linnoila
Markku Linnoila University of Helsinki
Qiaoping Yuan
Qiaoping Yuan National Institutes of Health
Melanie L. Schwandt
Melanie L. Schwandt National Institutes of Health
David A. Nielsen
David A. Nielsen Baylor College of Medicine
Jeffrey C. Long
Jeffrey C. Long University of New Mexico
Andrew W. Bergen
Andrew W. Bergen Oregon Research Institute
Joel Gelernter
Joel Gelernter Yale University
Anil K. Malhotra
Anil K. Malhotra Hofstra University
Stephen J. Suomi
Stephen J. Suomi National Institutes of Health

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