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Howard J. Edenberg

Howard J. Edenberg

D-Index & Metrics

Genetics

D-Index
127
Citations
56823
World Ranking
292
National Ranking
154

Medicine

D-Index
127
Citations
58408
World Ranking
2835
National Ranking
1578

Research.com Recognitions

  • 2007 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Howard J. Edenberg is affiliated with Indiana University in the United States. Their research primarily spans the fields of Medicine as well as Biochemistry, Genetics and Molecular Biology. Within these broad areas, their subfields of study include Genetics, Epidemiology, Pathology and Forensic Medicine, Molecular Biology, and Clinical Psychology.

Their scientific work covers various topics with a particular focus on genetic associations and epidemiology, substance abuse treatment and outcomes, and alcohol consumption and health effects. Additional subjects of interest include epigenetics and DNA methylation, neurotransmitter receptor influence on behavior, peroxisome proliferator-activated receptors, and cannabis and cannabinoid research.

Howard J. Edenberg has published extensively, contributing to multiple frequent venues such as bioRxiv (Cold Spring Harbor Laboratory), Molecular Psychiatry, European Neuropsychopharmacology, Translational Psychiatry, and Genes Brain & Behavior.

Notable recent papers include:

  • Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits (2020, Nature Neuroscience)
  • A large-scale genome-wide association study meta-analysis of cannabis use disorder (2020, The Lancet Psychiatry)
  • Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction (2021, Nature Neuroscience)
  • Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals (2023, Nature Medicine)
  • Leveraging genome-wide data to investigate differences between opioid use vs. opioid dependence in 41,176 individuals from the Psychiatric Genomics Consortium (2020, Molecular Psychiatry)

The scientist frequently collaborates with other researchers; key co-authors include Arpana Agrawal, Danielle M. Dick, Bernice Porjesz, Chella Kamarajan, and Dongbing Lai.

Howard J. Edenberg has been recognized as a Fellow of the American Association for the Advancement of Science (AAAS) since 2007.

Best Publications

  • Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

    S. Hong Lee;Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Stephen V. Faraone

  • Genome-wide association study identifies 30 loci associated with bipolar disorder

    Eli A. Stahl;Eli A. Stahl;Gerome Breen;Andreas J. Forstner;Andrew McQuillin

  • Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

    Pamela Sklar;Pamela Sklar;Stephan Ripke;Stephan Ripke;Laura J. Scott;Ole A. Andreassen

  • Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

    Niamh Mullins;Andreas J. Forstner;Andreas J. Forstner;Andreas J. Forstner;Kevin S. O'Connell;Kevin S. O'Connell;Brandon Coombes

  • Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

    Phil H. Lee;Verneri Anttila;Hyejung Won;Yen-Chen A. Feng

  • Genome‐wide search for genes affecting the risk for alcohol dependence

    Theodore Reich;Howard J. Edenberg;Alison Goate;Jeff T. Williams

  • The Genetics of Alcohol Metabolism: Role of Alcohol Dehydrogenase and Aldehyde Dehydrogenase Variants

    Howard J. Edenberg

  • Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

    Douglas M. Ruderfer;Stephan Ripke;Stephan Ripke;Stephan Ripke;Andrew McQuillin;James Boocock

  • Variations in GABRA2, Encoding the α2 Subunit of the GABAA Receptor, Are Associated with Alcohol Dependence and with Brain Oscillations

    Howard J. Edenberg;Danielle M. Dick;Xiaoling Xuei;Huijun Tian

  • Alcohol and aldehyde dehydrogenase genotypes and alcoholism in Chinese men.

    Holly Read Thomasson;Howard J. Edenberg;David W. Crabb;Xiao Ling Mai

  • Variants in nicotinic receptors and risk for nicotine dependence

    Laura Jean Bierut;Jerry A. Stitzel;Jen C. Wang;Anthony L. Hinrichs

  • Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

    Colm O'Dushlaine;Lizzy Rossin;Phil H. Lee;Laramie Duncan;Laramie Duncan

  • Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

    Raymond K. Walters;Raymond K. Walters;Renato Polimanti;Emma C. Johnson;Jeanette N. McClintick

  • Genotypes for aldehyde dehydrogenase deficiency and alcohol sensitivity. The inactive ALDH2(2) allele is dominant.

    D W Crabb;H J Edenberg;W F Bosron;T K Li

  • Psychiatric genomics: An update and an Agenda

    Patrick F. Sullivan;Arpana Agrawal;Cynthia M. Bulik;Ole A. Andreassen

  • Genome-wide Association Studies in Ancestrally Diverse Populations: Opportunities, Methods, Pitfalls, and Recommendations

    Roseann E. Peterson;Karoline Kuchenbaecker;Raymond K. Walters;Chia Yen Chen

  • Eukaryotic chromosome replication.

    Howard J. Edenberg;Joel A. Huberman

  • Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder.

    Ricardo Segurado;Sevilla D. Detera-Wadleigh;Douglas F. Levinson;Cathryn M. Lewis

  • Genotypes for Aldehyde Dehydrogenase Deficiency and Alcohol Sensitivity

    David W. Crabb;Howard J. Edenberg;William F. Bosron;Ting-Kai Li

  • Genome wide meta-analysis identifies genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders

    Lee Ph;Anttila;Won H

Frequent Co-Authors

John I. Nurnberger
John I. Nurnberger Indiana University
Tatiana Foroud
Tatiana Foroud Indiana University
Alison Goate
Alison Goate Icahn School of Medicine at Mount Sinai
Bernice Porjesz
Bernice Porjesz SUNY Downstate Medical Center
Marc A. Schuckit
Marc A. Schuckit University of California, San Diego
Danielle M. Dick
Danielle M. Dick Rutgers, The State University of New Jersey
Samuel Kuperman
Samuel Kuperman University of Iowa
Laura J. Bierut
Laura J. Bierut Washington University in St. Louis
Jay A. Tischfield
Jay A. Tischfield Rutgers, The State University of New Jersey
John P. Rice
John P. Rice Washington University in St. Louis

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