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Klaus-Peter Lesch

Klaus-Peter Lesch

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Medicine
Germany
2026

D-Index & Metrics

Medicine

D-Index
143
Citations
88320
World Ranking
1492
National Ranking
72

Research.com Recognitions

  • 2026 - Research.com Medicine in Germany Leader Award

Overview

Klaus-Peter Lesch is affiliated with the University of Würzburg in Germany. Their research contributions span several fields including Neuroscience, Biochemistry, Genetics and Molecular Biology, and Medicine. A significant portion of their work focuses on Psychiatry and Mental Health, Molecular Biology, and Genetics, with additional emphasis on Cognitive Neuroscience and Cellular and Molecular Neuroscience.

The scholar's research interests encompass a range of main topics including Attention Deficit Hyperactivity Disorder, Tryptophan and Brain Disorders, Genetics and Neurodevelopmental Disorders, Stress Responses and Cortisol, Neurotransmitter Receptor Influence on Behavior, Neuroendocrine Regulation and Behavior, and Functional Brain Connectivity Studies.

Recent publications by Klaus-Peter Lesch include the following papers:

  • Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains, 2023, Nature Genetics
  • Genetic architecture of 11 major psychiatric disorders at biobehavioral, functional genomic and molecular genetic levels of analysis, 2022, Nature Genetics
  • Chronic mild stress paradigm as a rat model of depression: facts, artifacts, and future perspectives, 2022, Psychopharmacology
  • Consortium neuroscience of attention deficit/hyperactivity disorder and autism spectrum disorder: The ENIGMA adventure, 2020, Human Brain Mapping
  • Shared genetic background between children and adults with attention deficit/hyperactivity disorder, 2020, Neuropsychopharmacology

Frequent coauthors collaborating with Klaus-Peter Lesch include:

  • Tatyana Strekalova
  • Andreas Reif
  • Georg Ziegler
  • Daniel C. Anthony
  • Anna Gorlova

The most common publication venues for their work are:

  • European Neuropsychopharmacology
  • Neuroscience Applied
  • Nature Genetics
  • Journal of Neural Transmission
  • Progress in Neuro-Psychopharmacology and Biological Psychiatry

Best Publications

  • Association of Anxiety-Related Traits with a Polymorphism in the Serotonin Transporter Gene Regulatory Region

    Klaus-Peter Lesch;Dietmar Bengel;Armin Heils;Sue Z. Sabol

  • Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

    Jordan W. Smoller;Kenneth Kendler;Nicholas John Craddock;Phil Hyoun Lee

  • Allelic Variation of Human Serotonin Transporter Gene Expression

    A Heils;A Teufel;S Petri;G Stöber

  • Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

    S. Hong Lee;Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Stephen V. Faraone

  • Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

    Ditte Demontis;Ditte Demontis;Raymond K Walters;Raymond K Walters;Joanna Martin;Joanna Martin;Joanna Martin;Manuel Mattheisen

  • Analysis of shared heritability in common disorders of the brain

    Verneri Anttila;Verneri Anttila;Brendan Bulik-Sullivan;Brendan Bulik-Sullivan;Hilary K. Finucane;Raymond K. Walters;Raymond K. Walters

  • Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

    Phil H. Lee;Verneri Anttila;Hyejung Won;Yen-Chen A. Feng

  • Long story short: the serotonin transporter in emotion regulation and social cognition.

    Turhan Canli;Klaus-Peter Lesch

  • Subcortical brain volume differences in participants with attention deficit hyperactivity disorder in children and adults: a cross-sectional mega-analysis

    Martine Hoogman;Janita Bralten;Derrek P. Hibar;Maarten Mennes

  • A novel functional polymorphism within the promoter of the serotonin transporter gene: possible role in susceptibility to affective disorders

    D. A. Collier;G. Stober;T. Li;A. Heils

  • Early experience and serotonin transporter gene variation interact to influence primate CNS function.

    A J Bennett;K P Lesch;A Heils;J C Long

  • Organization of the human serotonin transporter gene.

    K P Lesch;U Balling;J Gross;K Strauss

  • Altered Brain Serotonin Homeostasis and Locomotor Insensitivity to 3,4-Methylenedioxymethamphetamine (“Ecstasy”) in Serotonin Transporter-Deficient Mice

    Dietmar Bengel;Dennis L. Murphy;Anne M. Andrews;Christine H. Wichems

  • Neural stem cell proliferation is decreased in schizophrenia, but not in depression.

    Reif A;Fritzen S;Finger M;Strobel A

  • Excess of High Activity Monoamine Oxidase A Gene Promoter Alleles in Female Patients with Panic Disorder

    Jürgen Deckert;Marco Catalano;Yana V. Syagailo;Monica Bosi

  • Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

    Colm O'Dushlaine;Lizzy Rossin;Phil H. Lee;Laramie Duncan;Laramie Duncan

  • Primary structure of the human platelet serotonin uptake site: identity with the brain serotonin transporter.

    Klaus-Peter Lesch;Benjamin L. Wolozin;Dennis L. Murphy;Peter Riederer

  • Simultaneous genotyping of four functional loci of human SLC6A4, with a reappraisal of 5-HTTLPR and rs25531.

    J. R. Wendland;B. J. Martin;M. R. Kruse;K.-P. Lesch

  • Meta-Analysis of Genome-Wide Association Studies of Attention- Deficit/Hyperactivity Disorder

    Benjamin M. Neale;Benjamin M. Neale;Sarah E. Medland;Sarah E. Medland;Stephan Ripke;Stephan Ripke;Philip Asherson

  • Meta-analysis of brain-derived neurotrophic factor p.Val66Met in adult ADHD in four European populations†‡

    C. Sanchez-Mora;M. Ribases;J. A. Ramos-Quiroga;M. Casas

Frequent Co-Authors

Andreas Reif
Andreas Reif Goethe University Frankfurt
Tatyana Strekalova
Tatyana Strekalova Maastricht University
Barbara Franke
Barbara Franke Radboud University
Christian Jacob
Christian Jacob University of Würzburg
Jan K. Buitelaar
Jan K. Buitelaar Radboud University
Jan Haavik
Jan Haavik University of Bergen
Andreas J. Fallgatter
Andreas J. Fallgatter University of Tübingen
Marcel Romanos
Marcel Romanos University of Würzburg
Susanne Walitza
Susanne Walitza University of Zurich
Dennis L. Murphy
Dennis L. Murphy National Institutes of Health

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