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Research.com Recognitions

  • 2026 - Research.com Genetics in United States Leader Award
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  • 2024 - Research.com Genetics and Molecular Biology in Russia Leader Award
  • 2023 - Research.com Genetics in United States Leader Award
  • 2022 - Research.com Genetics and Molecular Biology in Russia Leader Award

Overview

Stephen J. O'Brien is affiliated with Nova Southeastern University in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with a significant focus on Medicine. Within these domains, their work emphasizes subfields such as Genetics, Molecular Biology, Ecology, Infectious Diseases, and Virology.

The main topics explored by Stephen J. O'Brien include genetic diversity and population structure, wildlife ecology and conservation, HIV research and treatment, genomics and phylogenetic studies, human-animal interaction studies, HIV/AIDS drug development and treatment, and hepatitis B virus studies.

Recent publications reflect a diverse range of interests and contributions to genomic and ecological research:

  • Genomic Adaptations and Evolutionary History of the Extinct Scimitar-Toothed Cat, Homotherium latidens (2020) in Current Biology
  • African and Asian leopards are highly differentiated at the genomic level (2021) in Current Biology
  • Genomic evidence for the Chinese mountain cat as a wildcat conspecific (Felis silvestris bieti) and its introgression to domestic cats (2021) in Science Advances
  • Single-haplotype comparative genomics provides insights into lineage-specific structural variation during cat evolution (2023) in Nature Genetics
  • Are pangolins scapegoats of the COVID-19 outbreak-CoV transmission and pathology evidence? (2020) in Conservation Letters

Stephen J. O'Brien frequently collaborates with the following coauthors:

  • Shu-Jin Luo
  • Agostinho Antunes
  • Klaus-Peter Koepfli
  • Nobuyuki Yamaguchi
  • Yan Zhuang

The scientist's work has been published primarily in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Current Biology
  • Nature Ecology & Evolution
  • Proceedings of the National Academy of Sciences
  • Journal of Heredity

Best Publications

  • Genetic Restriction of HIV-1 Infection and Progression to AIDS by a Deletion Allele of the CKR5 Structural Gene

    Michael Dean;Mary Carrington;Cheryl Winkler;Gavin A. Huttley

  • Towards complete and error-free genome assemblies of all vertebrate species

    Arang Rhie;Shane A. McCarthy;Shane A. McCarthy;Olivier Fedrigo;Joana Damas

  • Whole-genome analyses resolve early branches in the tree of life of modern birds

    Erich D. Jarvis;Siavash Mirarab;Andre J. Aberer;Bo Li;Bo Li;Bo Li

  • Resolution of the early placental mammal radiation using Bayesian phylogenetics

    William J. Murphy;Eduardo Eizirik;Eduardo Eizirik;Stephen J. O'Brien;Ole Madsen

  • Molecular phylogenetics and the origins of placental mammals

    William J. Murphy;Eduardo Eizirik;Eduardo Eizirik;Warren E. Johnson;Ya Ping Zhang

  • HLA and HIV-1: heterozygote advantage and B*35-Cw*04 disadvantage.

    Mary Carrington;George W. Nelson;Maureen P. Martin;Teri Kissner

  • A Molecular Phylogeny of Living Primates

    Polina L. Perelman;Warren E. Johnson;Christian Roos;Hector Seuanez

  • Epistatic interaction between KIR3DS1 and HLA-B delays the progression to AIDS

    Maureen P. Martin;Xiaojiang Gao;Jeong Hee Lee;George W. Nelson

  • HLA and NK Cell Inhibitory Receptor Genes in Resolving Hepatitis C Virus Infection

    Salim I. Khakoo;Chloe L. Thio;Maureen P. Martin;Collin R. Brooks

  • A molecular phylogeny for bats illuminates biogeography and the fossil record.

    Emma C. Teeling;Emma C. Teeling;Mark S. Springer;Ole Madsen;Paul Bates

  • Influence of combinations of human major histocompatibility complex genes on the course of HIV–1 infection

    Richard A. Kaslow;Mary Carrington;R. Apple;L. Park

  • Comparative genomics reveals insights into avian genome evolution and adaptation.

    Guojie Zhang;Guojie Zhang;Cai Li;Qiye Li;Bo Li

  • Genetic basis for species vulnerability in the Cheetah

    Stephen J. O'Brien;M. E. Roelke;L. Marker;A. Newman

  • Contrasting Genetic Influence of CCR2 and CCR5 Variants on HIV-1 Infection and Disease Progression

    Michael W. Smith;Michael Dean;Mary Carrington;Cheryl Winkler

  • Evaluation and Integration of Genetic Signature for Prediction Risk of Nasopharyngeal Carcinoma in Southern China

    Xiuchan Guo;Cheryl A. Winkler;Ji Li;Li Guan

  • The Influence of HLA Genotype on AIDS

    Mary Carrington;Stephen J. O'Brien

  • Placental mammal diversification and the Cretaceous–Tertiary boundary

    Mark S. Springer;William J. Murphy;Eduardo Eizirik;Stephen J. O'Brien

  • A canine distemper virus epidemic in Serengeti lions ( Panthera leo )

    Melody E. Roelke-Parker;Linda Munson;Craig Packer;Richard Kock

  • Genetic Restriction of AIDS Pathogenesis by an SDF-1 Chemokine Gene Variant

    Cheryl Winkler;William Modi;Michael W. Smith;George W. Nelson

  • Towards complete and error-free genome assemblies of all vertebrate species

    Arang Rhie;Shane A. McCarthy;Olivier Fedrigo;Joana Damas

Frequent Co-Authors

Warren E. Johnson
Warren E. Johnson Smithsonian Conservation Biology Institute
Mary Carrington
Mary Carrington Ragon Institute of MGH, MIT and Harvard
Russell F. Warren
Russell F. Warren Hospital for Special Surgery
William J. Murphy
William J. Murphy Texas A&M University
Agostinho Antunes
Agostinho Antunes University of Porto
Cheryl A. Winkler
Cheryl A. Winkler National Institutes of Health
Michael W. Smith
Michael W. Smith Johns Hopkins University
James J. Goedert
James J. Goedert National Institutes of Health
Eduardo Eizirik
Eduardo Eizirik Pontifical Catholic University of Rio Grande do Sul
David Vlahov
David Vlahov Yale University

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