Ching-Shih Chen

Research.com Recognitions

• 2014 - Fellow, National Academy of Inventors
• 2004 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Best Publications

• FTY720, a new alternative for treating blast crisis chronic myelogenous leukemia and Philadelphia chromosome–positive acute lymphocytic leukemia

  Paolo Neviani;Ramasamy Santhanam;Joshua J. Oaks;Anna M. Eiring

  418
  Citations

• Suberoylanilide Hydroxamic Acid Reactivates HIV From Latently Infected Cells

  Xavier Contreras;Marc Schweneker;Ching-Shih Chen;Joseph M. McCune

  407
  Citations

• Indole-3-carbinol as a chemopreventive and anti-cancer agent.

  Jing-Ru Weng;Chen-Hsun Tsai;Samuel K. Kulp;Ching-Shih Chen

  399
  Citations

• From the Cyclooxygenase-2 Inhibitor Celecoxib to a Novel Class of 3-Phosphoinositide-Dependent Protein Kinase-1 Inhibitors

  Jiuxiang Zhu;Jui Wen Huang;Ping Hui Tseng;Ya Ting Yang

  385
  Citations

• 3-phosphoinositide-dependent protein kinase-1/Akt signaling represents a major cyclooxygenase-2-independent target for celecoxib in prostate cancer cells.

  Samuel K. Kulp;Ya Ting Yang;Chin Chun Hung;Kuen Feng Chen

  359
  Citations

• Cyclooxygenase-2, Player or Spectator in Cyclooxygenase-2 Inhibitor-Induced Apoptosis in Prostate Cancer Cells

  Xueqin Song;Ho Pi Lin;Amy J. Johnson;Ping Hui Tseng

  335
  Citations

• Targeting histone deacetylase in cancer therapy

  Hsiang Yu Lin;Chang Shi Chen;Shuan Pei Lin;Jing Ru Weng

  265
  Citations

• Neutrophil gelatinase-associated lipocalin as a survival factor

  Zhimin Tong;Xuli Wu;Dmitriy Ovcharenko;Jiuxiang Zhu

  263
  Citations

• PP2A-activating drugs selectively eradicate TKI-resistant chronic myeloid leukemic stem cells

  Paolo Neviani;Jason G. Harb;Joshua J. Oaks;Ramasamy Santhanam

  256
  Citations

• Thiazolidenediones mediate apoptosis in prostate cancer cells in part through inhibition of Bcl-xL/Bcl-2 functions independently of PPARγ

  Chung Wai Shiau;Chih Cheng Yang;Samuel K. Kulp;Kuen Feng Chen

  243
  Citations

• Histone acetylation-independent effect of histone deacetylase inhibitors on Akt through the reshuffling of protein phosphatase 1 complexes.

  Chang Shi Chen;Shu Chuan Weng;Ping Hui Tseng;Ho Pi Lin

  239
  Citations

• Histone Deacetylase Inhibitors Sensitize Prostate Cancer Cells to Agents that Produce DNA Double-Strand Breaks by Targeting Ku70 Acetylation

  Chang Shi Chen;Yu Chieh Wang;Hsiao Ching Yang;Po Hsien Huang

  221
  Citations

• Using cyclooxygenase-2 inhibitors as molecular platforms to develop a new class of apoptosis-inducing agents.

  Jiuxiang Zhu;Xueqin Song;Ho-Pi Lin;Donn C. Young

  210
  Citations

• Small-Molecule Inhibitors of Phosphatidylinositol 3-Kinase/Akt Signaling Inhibit Wnt/β-Catenin Pathway Cross-Talk and Suppress Medulloblastoma Growth

  Ninib Baryawno;Baldur Sveinbjörnsson;Staffan Eksborg;Ching-Shih Chen

  198
  Citations

• OSU-03012, a Novel Celecoxib Derivative, Induces Reactive Oxygen Species–Related Autophagy in Hepatocellular Carcinoma

  Ming Gao;Pei Yen Yeh;Yen-Shen Lu;Chih-Hung Hsu

  195
  Citations

• Higher Doses of Lenalidomide Are Associated With Unacceptable Toxicity Including Life-Threatening Tumor Flare in Patients With Chronic Lymphocytic Leukemia

  Leslie A. Andritsos;Amy J. Johnson;Gerard Lozanski;William Blum

  181
  Citations

• AMPK Reverses the Mesenchymal Phenotype of Cancer Cells by Targeting the Akt–MDM2–Foxo3a Signaling Axis

  Chih-Chien Chou;Kuen-Haur Lee;I-Lu Lai;Dasheng Wang

  180
  Citations

• FTY720 demonstrates promising preclinical activity for chronic lymphocytic leukemia and lymphoblastic leukemia/lymphoma.

  Qing Liu;Xiaobin Zhao;Frank Frissora;Yihui Ma

  177
  Citations

• Peroxisome Proliferator-Activated Receptor γ-Independent Ablation of Cyclin D1 by Thiazolidinediones and Their Derivatives in Breast Cancer Cells

  Jui Wen Huang;Chung Wai Shiau;Ya Ting Yang;Samuel K. Kulp

  176
  Citations

• Increased PTEN expression due to transcriptional activation of PPARγ by Lovastatin and Rosiglitazone

  Rosemary E. Teresi;Chung-Wai Shaiu;Ching-Shih Chen;V. Krishna Chatterjee

  168
  Citations