Adly Yacoub

Overview

Best Publications

• MAPK pathways in radiation responses.

  Paul Dent;Adly Yacoub;Paul B Fisher;Michael P Hagan

  837
  Citations

• Stress and radiation-induced activation of multiple intracellular signaling pathways.

  Paul Dent;Adly Yacoub;Joseph Contessa;Ruben Caron

  612
  Citations

• Radiation-induced cell signaling: inside-out and outside-in

  Kristoffer Valerie;Adly Yacoub;Michael P. Hagan;David T. Curiel

  411
  Citations

• Mutations in the Phosphatidylinositol-3-Kinase Pathway Predict for Antitumor Activity of the Inhibitor PX-866 whereas Oncogenic Ras Is a Dominant Predictor for Resistance

  Nathan T. Ihle;Robert Lemos;Peter Wipf;Adly Yacoub

  324
  Citations

• Melanoma differentiation associated gene-7, mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.

  Zao-Zhong Su;Irina V Lebedeva;Devanand Sarkar;Rahul V Gopalkrishnan

  244
  Citations

• Epidermal growth factor and ionizing radiation up-regulate the DNA repair genes XRCC1 and ERCC1 in DU145 and LNCaP prostate carcinoma through MAPK signaling

  Adly Yacoub;Robert McKinstry;Darin Hinman;Theodore Chung

  210
  Citations

• Mitochondrial localized Stat3 promotes breast cancer growth via phosphorylation of serine 727.

  Qifang Zhang;Vidisha Raje;Vasily A. Yakovlev;Adly Yacoub

  196
  Citations

• Inhibition of the MAPK and PI3K pathways enhances UDCA-induced apoptosis in primary rodent hepatocytes

  Liang Qiao;Adly Yacoub;Elaine Studer;Seema Gupta

  192
  Citations

• Autocrine loops with positive feedback enable context-dependent cell signaling

  Stanislav Yefimovic Shvartsman;M. P. Hagan;A. Yacoub;P. Dent

  185
  Citations

• Ionizing radiation modulates vascular endothelial growth factor (VEGF) expression through multiple mitogen activated protein kinase dependent pathways.

  Jong-Sung Park;Liang Qiao;Zao-Zong Su;Darin Hinman

  182
  Citations

• Vorinostat and sorafenib synergistically kill tumor cells via FLIP suppression and CD95 activation

  Guo Zhang;Margaret A. Park;Clint Mitchell;Hossein Hamed

  155
  Citations

• mda-7/IL-24: exploiting cancer's Achilles' heel.

  Irina V. Lebedeva;Moira Sauane;Rahul V. Gopalkrishnan;Devanand Sarkar

  155
  Citations

• Astrocyte elevated gene-1: a novel target for human glioma therapy.

  Luni Emdad;Devanand Sarkar;Seok-Geun Lee;Zhao Zhong Su

  150
  Citations

• Mechanism of Autophagy to Apoptosis Switch Triggered in Prostate Cancer Cells by Antitumor Cytokine Melanoma Differentiation-Associated Gene 7/Interleukin-24

  Sujit K. Bhutia;Rupesh Dash;Swadesh K. Das;Belal Azab

  149
  Citations

• A Drosophila ribosomal protein contains 8-oxoguanine and abasic site DNA repair activities.

  Adly Yacoub;Laura Augeri;Mark Kelley;Paul W. Doetsch

  141
  Citations

• Sorafenib enhances pemetrexed cytotoxicity through an autophagy -dependent mechanism in cancer cells

  M. Danielle Bareford;Margaret A. Park;Adly Yacoub;Hossein A. Hamed

  137
  Citations

• mda-7/IL-24: a unique member of the IL-10 gene family promoting cancer-targeted toxicity.

  Rupesh Dash;Sujit K. Bhutia;Belal Azab;Zhao zhong Su

  136
  Citations

• RLIP76 is a major determinant of radiation sensitivity.

  Sanjay Awasthi;Sharad S. Singhal;Sushma Yadav;Jyotsana Singhal

  136
  Citations

• Vorinostat and sorafenib increase CD95 activation in gastrointestinal tumor cells through a Ca(2+)-de novo ceramide-PP2A-reactive oxygen species-dependent signaling pathway.

  Margaret A. Park;Clint Mitchell;Guo Zhang;Adly Yacoub

  132
  Citations

• The DNA Repair Activity of Human Redox/Repair Protein APE/Ref-1 Is Inactivated by Phosphorylation

  Adly Yacoub;Mark R. Kelley;Walter A. Deutsch

  129
  Citations