The scientist’s investigation covers issues in Cancer research, Cell biology, Signal transduction, MAPK/ERK pathway and Autocrine signalling. His study in Cancer research is interdisciplinary in nature, drawing from both Carcinogenesis, Cellular Dedifferentiation and Radioprotective Agent. His Cell biology research incorporates elements of Cell, Transcription factor and Radiation induced.
His Signal transduction study integrates concerns from other disciplines, such as Cancer cell, Ceramide and Kinase. His MAPK/ERK pathway study combines topics from a wide range of disciplines, such as Ursodeoxycholic acid, Endocrinology, Deoxycholic acid and Fas ligand. His research integrates issues of Epidermal growth factor and Growth factor receptor in his study of Autocrine signalling.
His primary areas of study are Cancer research, Cell biology, Signal transduction, Protein kinase B and Molecular biology. His biological study spans a wide range of topics, including Autophagy, Apoptosis, Programmed cell death and Immunology. His study connects Caspase and Cell biology.
The Signal transduction study combines topics in areas such as Cancer cell, Cell cycle and Ceramide. His Protein kinase B research includes elements of XIAP, PI3K/AKT/mTOR pathway, Radiosensitivity and Transfection. He has included themes like DNA glycosylase, DNA damage, DNA repair, AP site and Adenoviridae in his Molecular biology study.
Adly Yacoub mainly investigates Cancer research, Apoptosis, Molecular biology, Signal transduction and Cell biology. His Cancer research study integrates concerns from other disciplines, such as Autophagy and Programmed cell death. His work in the fields of Apoptosis, such as Fas receptor, overlaps with other areas such as Cell killing.
Adly Yacoub works mostly in the field of Molecular biology, limiting it down to concerns involving Adenoviridae and, occasionally, Virus and Gene delivery. His research investigates the connection with Signal transduction and areas like Ceramide which intersect with concerns in Sphingolipid and Toxicity. His research on Cell biology frequently links to adjacent areas such as Cell growth.
His primary areas of investigation include Cancer research, Autophagy, Signal transduction, Kinase and Sorafenib. His work deals with themes such as Molecular biology and Ceramide, which intersect with Cancer research. In Autophagy, Adly Yacoub works on issues like Cancer cell, which are connected to Interleukin 10, Melanoma, Immune system and Cytokine.
He has researched Signal transduction in several fields, including CHEK1, Cell cycle checkpoint, DNA damage and Poly Polymerase Inhibitor. The concepts of his Kinase study are interwoven with issues in Carcinogenesis, Ceramide synthase and Ral Guanine Nucleotide Exchange Factor. His study in Programmed cell death is interdisciplinary in nature, drawing from both Unfolded protein response and Cell biology.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
MAPK pathways in radiation responses
Paul Dent;Adly Yacoub;Paul B Fisher;Michael P Hagan.
Stress and radiation-induced activation of multiple intracellular signaling pathways.
Paul Dent;Adly Yacoub;Joseph Contessa;Ruben Caron.
Radiation Research (2003)
Radiation-induced cell signaling: inside-out and outside-in
Kristoffer Valerie;Adly Yacoub;Michael P. Hagan;David T. Curiel.
Molecular Cancer Therapeutics (2007)
Mutations in the Phosphatidylinositol-3-Kinase Pathway Predict for Antitumor Activity of the Inhibitor PX-866 whereas Oncogenic Ras Is a Dominant Predictor for Resistance
Nathan T. Ihle;Robert Lemos;Peter Wipf;Adly Yacoub.
Cancer Research (2009)
Melanoma differentiation associated gene-7, mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.
Zao-Zhong Su;Irina V Lebedeva;Devanand Sarkar;Rahul V Gopalkrishnan.
Epidermal growth factor and ionizing radiation up-regulate the DNA repair genes XRCC1 and ERCC1 in DU145 and LNCaP prostate carcinoma through MAPK signaling
Adly Yacoub;Robert McKinstry;Darin Hinman;Theodore Chung.
Radiation Research (2003)
Inhibition of the MAPK and PI3K pathways enhances UDCA-induced apoptosis in primary rodent hepatocytes
Liang Qiao;Adly Yacoub;Elaine Studer;Seema Gupta.
Autocrine loops with positive feedback enable context-dependent cell signaling.
Stanislav Yefimovic Shvartsman;M. P. Hagan;A. Yacoub;P. Dent.
American Journal of Physiology-cell Physiology (2002)
Mitochondrial localized Stat3 promotes breast cancer growth via phosphorylation of serine 727.
Qifang Zhang;Vidisha Raje;Vasily A. Yakovlev;Adly Yacoub.
Journal of Biological Chemistry (2013)
Ionizing radiation modulates vascular endothelial growth factor (VEGF) expression through multiple mitogen activated protein kinase dependent pathways.
Jong-Sung Park;Liang Qiao;Zao-Zong Su;Darin Hinman.
If you think any of the details on this page are incorrect, let us know.
We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below: