World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
60
Citations
9603
World Ranking
12212
National Ranking
5215

Overview

Sunil Chada is affiliated with The University of Texas MD Anderson Cancer Center in the United States. Their research primarily focuses on Medicine and Biochemistry, Genetics and Molecular Biology, with a specialization in Oncology, Genetics, and Biotechnology. Additional subfields include Surgery and Agronomy and Crop Science.

The scientist's work spans diverse topics including Cancer Immunotherapy and Biomarkers, Cancer Research and Treatments, Virus-based gene therapy research, CAR-T cell therapy research, Cancer-related Molecular Pathways, Animal Disease Management and Epidemiology, and Plant and Fungal Interactions Research.

Recent publications by Sunil Chada include:

  • Tumor suppressor immune gene therapy to reverse immunotherapy resistance (2021, Cancer Gene Therapy)
  • Tumor Suppressor Immune Gene Therapy to Reverse Immunotherapy Resistance (2021, bioRxiv (Cold Spring Harbor Laboratory))

Frequent coauthors in their research collaborations are:

  • Dora Wiederhold
  • Kerstin B. Menander
  • Beatha Sellman
  • Max W. Talbott
  • John Nemunaitis

Their publications have appeared in several scientific venues, with notable frequency in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • Cancer Gene Therapy
  • Frontiers in Oncology
  • Endocrine Abstracts

Sunil Chada's research contributions feature analyses of gene therapy clinical trials and immune gene therapies aimed at overcoming resistance in cancer treatments. Their work investigates approaches such as adenoviral p53 gene therapy and tumor suppressor immune gene therapy with implications for recurrent head and neck squamous cell carcinoma and immunotherapy-resistant cancers.

Best Publications

  • Combination of p53 cancer vaccine with chemotherapy in patients with extensive stage small cell lung cancer

    Scott J. Antonia;Noweeda Mirza;Ingo Fricke;Alberto Chiappori

  • The Protein Product of the Tumor Suppressor Gene, Melanoma Differentiation-Associated Gene 7, Exhibits Immunostimulatory Activity and Is Designated IL-24

    Eva G. Caudell;John B. Mumm;Nancy Poindexter;Suhendan Ekmekcioglu

  • Genomic structure, chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth suppressing and apoptosis inducing properties.

    Eric Y Huang;Malavi T Madireddi;Malavi T Madireddi;Rahul V Gopalkrishnan;Magdalena Leszczyniecka

  • Intratumoral Injection of INGN 241, a Nonreplicating Adenovector Expressing the Melanoma-Differentiation Associated Gene-7 (mda-7/IL24): Biologic Outcome in Advanced Cancer Patients

    Alex W. Tong;John Nemunaitis;Dan Su;Yuan Zhang

  • Clinical and local biological effects of an intratumoral injection of mda-7 (IL24; INGN 241) in patients with advanced carcinoma: a phase I study

    C. Casey Cunningham;Sunil Chada;James A. Merritt;Alex Tong

  • Melanoma differentiation-associated gene 7/interleukin (IL)-24 is a novel ligand that regulates angiogenesis via the IL-22 receptor.

    Rajagopal Ramesh;Abner M. Mhashilkar;Fumihiro Tanaka;Yuji Saito

  • Inhibition of human lung cancer growth following adenovirus-mediated mda-7 gene expression in vivo

    Tomoyuki Saeki;Abner Mhashilkar;Xin Swanson;X Helena Zou-Yang

  • Melanoma differentiation associated gene-7 (mda-7): a novel anti-tumor gene for cancer gene therapy.

    Abner M. Mhashilkar;Robert D. Schrock;Mustafa Hindi;Jennifer Liao

  • mda-7/IL-24, a novel cancer selective apoptosis inducing cytokine gene: from the laboratory into the clinic.

    Paul B. Fisher;Rahul V. Gopalkrishnan;Sunil Chada;Rajagopal Ramesh

  • The anthelmintic drug mebendazole induces mitotic arrest and apoptosis by depolymerizing tubulin in non-small cell lung cancer cells.

    Ji Ichiro Sasaki;Rajagopal Ramesh;Sunil Chada;Yoshihito Gomyo

  • Tumor-suppressive effects by adenovirus-mediated mda-7 gene transfer in non-small cell lung cancer cell in vitro.

    T. Saeki;A. Mhashilkar;S. Chada;C. Branch

  • Loss of MDA-7 Expression With Progression of Melanoma

    Julie A. Ellerhorst;Victor G. Prieto;Suhendan Ekmekcioglu;Lyle Broemeling

  • Adenoviral Transfer of the Melanoma Differentiation-associated Gene 7 (mda7) Induces Apoptosis of Lung Cancer Cells via Up-Regulation of the Double-Stranded RNA-dependent Protein Kinase (PKR)

    Abujiang Pataer;Stephan A. Vorburger;Glen N. Barber;Sunil Chada

  • MDA-7/IL-24 is a unique cytokine--tumor suppressor in the IL-10 family.

    Sunil Chada;R. Bryan Sutton;Suhendan Ekmekcioglu;Julie Ellerhorst

  • Down‐regulated melanoma differentiation associated gene (mda‐7) expression in human melanomas

    Suhendan Ekmekcioglu;Julie Ellerhorst;Abner M. Mhashilkar;Aysegul A. Sahin

  • Adenovirus-mediated wild-type p53 tumor suppressor gene therapy induces apoptosis and suppresses growth of human pancreatic cancer [seecomments].

    Michael Bouvet;Richard J. Bold;Julia Lee;Douglas B. Evans

  • Ectopic production of MDA-7/IL-24 inhibits invasion and migration of human lung cancer cells.

    Rajagopal Ramesh;Isao Ito;Began Gopalan;Yuji Saito

  • Adenovirus-mediated mda-7 (IL24) gene therapy suppresses angiogenesis and sensitizes NSCLC xenograft tumors to radiation.

    Takashi Nishikawa;Rajagopal Ramesh;Anupama Munshi;Sunil Chada

  • Bystander activity of Ad-mda7: Human MDA-7 protein kills melanoma cells via an IL-20 receptor-dependent but STAT3-independent mechanism

    Sunil Chada;Abner M. Mhashilkar;Rajagopal Ramesh;John B. Mumm

  • MDA-7 negatively regulates the β-catenin and PI3K signaling pathways in breast and lung tumor cells

    Abner M. Mhashilkar;Alexis L. Stewart;Kerry Sieger;Heng Yin Yang

Frequent Co-Authors

Rajagopal Ramesh
Rajagopal Ramesh University of Oklahoma Health Sciences Center
Jack A. Roth
Jack A. Roth The University of Texas MD Anderson Cancer Center
Elizabeth A. Grimm
Elizabeth A. Grimm The University of Texas MD Anderson Cancer Center
John Nemunaitis
John Nemunaitis Gradalis (United States)
Raymond E. Meyn
Raymond E. Meyn The University of Texas MD Anderson Cancer Center
Kelly K. Hunt
Kelly K. Hunt The University of Texas MD Anderson Cancer Center
Dmitry I. Gabrilovich
Dmitry I. Gabrilovich AstraZeneca (United Kingdom)
Scott J. Antonia
Scott J. Antonia Duke University
Neil Senzer
Neil Senzer Gradalis (United States)
Paul B. Fisher
Paul B. Fisher Virginia Commonwealth University

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