D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 75 Citations 27,393 275 World Ranking 2242 National Ranking 1224
Medicine D-index 74 Citations 23,114 289 World Ranking 12461 National Ranking 6609

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • Enzyme

The scientist’s investigation covers issues in Cancer research, Apoptosis, Cell biology, Protein kinase B and Kinase. His Cancer research study combines topics in areas such as Jurkat cells, XIAP, Histone deacetylase inhibitor, Sodium butyrate and Leukemia. Steven Grant has researched Apoptosis in several fields, including Molecular biology, Endocrinology and Myeloid leukemia.

His Cell biology research includes elements of Cell cycle and Downregulation and upregulation. His Protein kinase B research incorporates themes from Radiosensitivity, PI3K/AKT/mTOR pathway, Cell killing and Bcl-2-associated X protein. He combines subjects such as Autophagy, Unfolded protein response, Endoplasmic reticulum and Ceramide with his study of Programmed cell death.

His most cited work include:

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (4170 citations)
  • MAPK pathways in radiation responses (496 citations)
  • Stress and radiation-induced activation of multiple intracellular signaling pathways. (426 citations)

What are the main themes of his work throughout his whole career to date?

Steven Grant mostly deals with Cancer research, Apoptosis, Cell biology, Programmed cell death and Molecular biology. His work deals with themes such as Protein kinase B, Leukemia, Immunology, Vorinostat and Kinase, which intersect with Cancer research. His Apoptosis research is multidisciplinary, incorporating perspectives in Cell culture, Downregulation and upregulation and Bortezomib.

His Cell biology research integrates issues from Autophagy and Caspase. Many of his studies involve connections with topics such as Ceramide and Programmed cell death. His Molecular biology research incorporates elements of Biochemistry, Transfection and Cytotoxicity.

He most often published in these fields:

  • Cancer research (58.45%)
  • Apoptosis (31.40%)
  • Cell biology (19.08%)

What were the highlights of his more recent work (between 2012-2021)?

  • Cancer research (58.45%)
  • Bortezomib (13.53%)
  • Apoptosis (31.40%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Cancer research, Bortezomib, Apoptosis, Pharmacology and Protein kinase B. His Cancer research research is multidisciplinary, relying on both Vorinostat, Histone deacetylase and Leukemia, Immunology. His research on Bortezomib also deals with topics like

  • Proteasome inhibitor that connect with fields like XIAP and Cell killing,
  • Haematopoiesis and related Stromal cell.

Programmed cell death and Autophagy are the primary areas of interest in his Apoptosis study. His work carried out in the field of Pharmacology brings together such families of science as Fas receptor, FADD, Chemotherapy and In vivo. Steven Grant works mostly in the field of Protein kinase B, limiting it down to concerns involving PI3K/AKT/mTOR pathway and, occasionally, Regorafenib and Kinase.

Between 2012 and 2021, his most popular works were:

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (4170 citations)
  • Histone deacetylase inhibitor (HDACI) mechanisms of action: emerging insights (150 citations)
  • Dual Inhibition of Bcl-2 and Bcl-xL Strikingly Enhances PI3K Inhibition-Induced Apoptosis in Human Myeloid Leukemia Cells through a GSK3- and Bim-Dependent Mechanism (105 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • Enzyme

His main research concerns Cancer research, Apoptosis, Molecular biology, Gene knockdown and Protein kinase B. His research integrates issues of Leukemia, Immunology, PI3K/AKT/mTOR pathway and Programmed cell death in his study of Cancer research. Steven Grant interconnects Downregulation and upregulation and Cell biology in the investigation of issues within Apoptosis.

His Molecular biology study combines topics from a wide range of disciplines, such as Unfolded protein response, Transfection and OSU-03012. His Protein kinase B research includes themes of Sphingosine, Cell growth and MAPK/ERK pathway. The study incorporates disciplines such as Small hairpin RNA and Computational biology in addition to Autophagy.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin.
Autophagy (2016)

7788 Citations

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin.
Autophagy (2016)

4781 Citations

MAPK pathways in radiation responses

Paul Dent;Adly Yacoub;Paul B Fisher;Michael P Hagan.
Oncogene (2003)

764 Citations

Induction of apoptotic DNA damage and cell death by activation of the sphingomyelin pathway.

W D Jarvis;R N Kolesnick;F A Fornari;R S Traylor.
Proceedings of the National Academy of Sciences of the United States of America (1994)

630 Citations

Stress and radiation-induced activation of multiple intracellular signaling pathways.

Paul Dent;Adly Yacoub;Joseph Contessa;Ruben Caron.
Radiation Research (2003)

594 Citations

Induction of Apoptotic DNA Fragmentation and Cell Death in HL-60 Human Promyelocytic Leukemia Cells by Pharmacological Inhibitors of Protein Kinase C

Jarvis Wd;Turner Aj;Povirk Lf;Traylor Rs.
Cancer Research (1994)

547 Citations

Mcl-1 down-regulation potentiates ABT-737 lethality by cooperatively inducing Bak activation and Bax translocation.

Shuang Chen;Yun Dai;Hisashi Harada;Paul Dent.
Cancer Research (2007)

510 Citations

Induction of apoptosis in U937 human leukemia cells by suberoylanilide hydroxamic acid (SAHA) proceeds through pathways that are regulated by Bcl-2/Bcl-XL, c-Jun, and p21CIP1, but independent of p53.

J A Vrana;R H Decker;C R Johnson;Z Wang.
Oncogene (1999)

406 Citations

Radiation-induced cell signaling: inside-out and outside-in

Kristoffer Valerie;Adly Yacoub;Michael P. Hagan;David T. Curiel.
Molecular Cancer Therapeutics (2007)

365 Citations

Apoptosis Induced by the Kinase Inhibitor BAY 43-9006 in Human Leukemia Cells Involves Down-regulation of Mcl-1 through Inhibition of Translation

Mohamed Rahmani;Eric Maynard Davis;Cheryl Bauer;Paul Dent.
Journal of Biological Chemistry (2005)

343 Citations

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