World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
109
Citations
40739
World Ranking
1012
National Ranking
612

Sheldon Milstien publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Sheldon Milstien sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 286 publications — 76th percentile

76% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Sheldon Milstien D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Sheldon Milstien sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 109 D-Index — 95th percentile

95% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Sheldon Milstien is affiliated with Virginia Commonwealth University in the United States. Their research spans fields including Biochemistry, Genetics and Molecular Biology, and Medicine, with a primary focus on Molecular Biology and related subfields such as Physiology, Endocrine and Autonomic Systems, Epidemiology, and Oncology.

The main topics covered in Milstien's work include:

  • Sphingolipid Metabolism and Signaling
  • Asthma and respiratory diseases
  • Circadian rhythm and melatonin
  • Lysosomal Storage Disorders Research
  • Calcium signaling and nucleotide metabolism
  • Autophagy in Disease and Therapy
  • Cancer Cells and Metastasis

Their published papers cover various aspects of these topics. Notable recent papers include:

  • "Ceramide in apoptosis and oxidative stress in allergic inflammation and asthma," 2020, Journal of Allergy and Clinical Immunology
  • "Targeting defective sphingosine kinase 1 in Niemann-Pick type C disease with an activator mitigates cholesterol accumulation," 2020, Journal of Biological Chemistry
  • "Sphingosine Kinase 2 in Stromal Fibroblasts Creates a Hospitable Tumor Microenvironment in Breast Cancer," 2022, Cancer Research
  • "Neutrophilia in severe asthma is reduced in Ormdl3 overexpressing mice," 2023, The FASEB Journal
  • "Sphingosine kinases regulate ER contacts with late endocytic organelles and cholesterol trafficking," 2022, Proceedings of the National Academy of Sciences

Frequent collaborators in these endeavors include:

  • Cynthia Weigel
  • Elisa N.D. Palladino
  • Sarah Spiegel
  • Christopher D. Green
  • Briana N. James

Sheldon Milstien's research contributions have been published across respected venues such as the Journal of Allergy and Clinical Immunology, Journal of Biological Chemistry, Cancer Research, The FASEB Journal, and Proceedings of the National Academy of Sciences.

Best Publications

  • Sphingosine-1-phosphate: an enigmatic signalling lipid

    Sarah Spiegel;Sheldon Milstien

  • Regulation of Histone Acetylation in the Nucleus by Sphingosine-1-Phosphate

    Nitai C. Hait;Jeremy Allegood;Michael Maceyka;Graham M. Strub

  • Sphingosine-1-phosphate signaling and its role in disease

    Michael Maceyka;Kuzhuvelil B. Harikumar;Sheldon Milstien;Sarah Spiegel

  • Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2

    Sergio E. Alvarez;Kuzhuvelil B. Harikumar;Nitai C. Hait;Jeremy Allegood

  • The outs and the ins of sphingosine-1-phosphate in immunity

    Sarah Spiegel;Sheldon Milstien

  • “Inside-Out” Signaling of Sphingosine-1-Phosphate: Therapeutic Targets

    Kazuaki Takabe;Steven W. Paugh;Sheldon Milstien;Sarah Spiegel

  • Molecular Cloning and Functional Characterization of a Novel Mammalian Sphingosine Kinase Type 2 Isoform

    Hong Liu;Masako Sugiura;Victor E. Nava;Lisa C. Edsall

  • Sphingosine 1-phosphate, a key cell signaling molecule.

    Sarah Spiegel;Sheldon Milstien

  • SphK1 and SphK2, Sphingosine Kinase Isoenzymes with Opposing Functions in Sphingolipid Metabolism

    Michael Maceyka;Heidi Sankala;Nitai C. Hait;Hervé Le Stunff

  • Sphingosine kinase, sphingosine-1-phosphate, and apoptosis.

    Michael Maceyka;Shawn G Payne;Sheldon Milstien;Sarah Spiegel

  • Oxidation of Tetrahydrobiopterin by Peroxynitrite: Implications for Vascular Endothelial Function

    Sheldon Milstien;Zvonimir Katusic

  • Role of the Sphingosine-1-Phosphate Receptor EDG-1 in PDGF-Induced Cell Motility

    John P. Hobson;Hans M. Rosenfeldt;Larry S. Barak;Ana Olivera

  • Sphingosine kinases, sphingosine 1-phosphate, apoptosis and diseases.

    Nitai C. Hait;Carole A. Oskeritzian;Steven W. Paugh;Sheldon Milstien

  • Sphingosine-1-Phosphate Links Persistent STAT3 Activation, Chronic Intestinal Inflammation, and Development of Colitis-Associated Cancer

    Jie Liang;Masayuki Nagahashi;Eugene Y. Kim;Kuzhuvelil B. Harikumar

  • Targeting the sphingosine-1-phosphate axis in cancer, inflammation and beyond

    Gregory T. Kunkel;Michael Maceyka;Sheldon Milstien;Sarah Spiegel

  • Sphingosine 1-Phosphate Stimulates Cell Migration through a Gi-coupled Cell Surface Receptor POTENTIAL INVOLVEMENT IN ANGIOGENESIS

    Fang Wang;James R. Van Brocklyn;John P. Hobson;Sharareh Movafagh

  • Regulation of nitric oxide synthesis by proinflammatory cytokines in human umbilical vein endothelial cells. Elevations in tetrahydrobiopterin levels enhance endothelial nitric oxide synthase specific activity.

    Pnina Rosenkranz-Weiss;William C. Sessa;Sheldon Milstien;Seymour Kaufman

  • Role of ABCC1 in export of sphingosine-1-phosphate from mast cells.

    Poulami Mitra;Carole A. Oskeritzian;Shawn G. Payne;Michael A. Beaven

  • Sphingosine kinase type 2 is a putative BH3-Only protein that induces apoptosis

    Hong Liu;Rachelle E. Toman;Rachelle E. Toman;Sravan K. Goparaju;Michael Maceyka

  • Apoptosis induces expression of sphingosine kinase 1 to release sphingosine-1-phosphate as a “come-and-get-me” signal

    David R. Gude;Sergio E. Alvarez;Steven W. Paugh;Poulami Mitra

Frequent Co-Authors

Sarah Spiegel
Sarah Spiegel Virginia Commonwealth University
Kazuaki Takabe
Kazuaki Takabe Roswell Park Cancer Institute
Seymour Kaufman
Seymour Kaufman National Institutes of Health
Jeremy C. Allegood
Jeremy C. Allegood Virginia Commonwealth University
Melvyn P. Heyes
Melvyn P. Heyes National Institutes of Health
Ana Olivera
Ana Olivera National Institutes of Health
Kuniaki Saito
Kuniaki Saito Fujita Health University
Itaru Endo
Itaru Endo Yokohama City University
John J. Ryan
John J. Ryan Virginia Commonwealth University

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