What is he best known for?
The fields of study he is best known for:
Sheldon Milstien focuses on Sphingosine, Cell biology, Sphingosine-1-phosphate, Sphingosine kinase and Biochemistry.
His Sphingosine study incorporates themes from Cancer research and Kinase.
His Cell biology study integrates concerns from other disciplines, such as Receptor, Chemotaxis, Lipid signaling and Apoptosis.
His Sphingosine-1-phosphate study combines topics in areas such as Autocrine signalling, Cell growth, Immune system, Signal transduction and Degranulation.
The various areas that Sheldon Milstien examines in his Sphingosine kinase study include Sphingolipid, Protein kinase B, Ceramide and Receptor tyrosine kinase.
His work in the fields of Phosphorylation, Superoxide and Oxidative stress overlaps with other areas such as Histone code.
His most cited work include:
- Sphingosine-1-phosphate: an enigmatic signalling lipid (1704 citations)
- Regulation of Histone Acetylation in the Nucleus by Sphingosine-1-Phosphate (699 citations)
- Sphingosine-1-phosphate signaling and its role in disease (666 citations)
What are the main themes of his work throughout his whole career to date?
Sheldon Milstien spends much of his time researching Cell biology, Sphingosine, Biochemistry, Sphingosine-1-phosphate and Sphingosine kinase.
His Cell biology research includes elements of Receptor and Lipid signaling.
His Sphingosine research includes themes of Kinase and Pharmacology.
As a member of one scientific family, Sheldon Milstien mostly works in the field of Sphingosine-1-phosphate, focusing on Autocrine signalling and, on occasion, Paracrine signalling.
As a part of the same scientific study, Sheldon Milstien usually deals with the Sphingosine kinase 1, concentrating on Cancer research and frequently concerns with Cancer, Cancer cell and Protein kinase B.
His Sphingolipid research is multidisciplinary, incorporating perspectives in Ceramide, Sphingomyelin and Second messenger system.
He most often published in these fields:
- Cell biology (35.71%)
- Sphingosine (32.71%)
- Biochemistry (32.33%)
What were the highlights of his more recent work (between 2013-2021)?
- Cancer research (17.29%)
- Sphingosine-1-phosphate (31.58%)
- Sphingosine (32.71%)
In recent papers he was focusing on the following fields of study:
Sheldon Milstien mostly deals with Cancer research, Sphingosine-1-phosphate, Sphingosine, Sphingosine kinase 1 and Breast cancer.
His Sphingosine-1-phosphate study combines topics from a wide range of disciplines, such as Chemokine and Metastasis.
His work carried out in the field of Sphingosine brings together such families of science as Sphingolipid, Kinase and Histone.
His Sphingolipid study is concerned with Biochemistry in general.
His study in Sphingosine kinase 1 is interdisciplinary in nature, drawing from both Cancer cell, Lipid signaling and Cell biology.
His Cell biology research is multidisciplinary, incorporating elements of Sphingosine kinase and Immune system.
Between 2013 and 2021, his most popular works were:
- Active, phosphorylated fingolimod inhibits histone deacetylases and facilitates fear extinction memory (133 citations)
- K63-linked polyubiquitination of transcription factor IRF1 is essential for IL-1-induced production of chemokines CXCL10 and CCL5 (85 citations)
- Targeting the SphK1/S1P/S1PR1 Axis That Links Obesity, Chronic Inflammation, and Breast Cancer Metastasis (68 citations)
In his most recent research, the most cited papers focused on:
His primary areas of study are Sphingosine, Cancer research, Breast cancer, Sphingosine-1-phosphate and Cancer.
His Sphingosine research integrates issues from Epigenetics in learning and memory, Acetylation, Sphingolipid, Histone deacetylase inhibitor and HDAC1.
The Sphingolipid study which covers Autoimmune disease that intersects with Inflammation.
His research in Breast cancer intersects with topics in Estrogen and Sphingosine kinase 1.
He interconnects Lipid signaling, Sphingomyelin and Endosome in the investigation of issues within Sphingosine kinase 1.
His research investigates the connection between Sphingosine-1-phosphate and topics such as Immunology that intersect with issues in S1PR2 and STAT3.
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