What is she best known for?
The fields of study she is best known for:
Her primary areas of investigation include Sphingosine, Cell biology, Sphingosine kinase 1, Sphingosine-1-phosphate and Biochemistry.
Her Sphingosine research includes themes of Cancer research and Kinase.
Susan Pyne works mostly in the field of Cell biology, limiting it down to concerns involving Platelet-derived growth factor receptor and, occasionally, Receptor tyrosine kinase, Receptor complex and Growth factor receptor.
Her Sphingosine kinase 1 research integrates issues from Endocrinology, Apoptosis, Proteasome, LNCaP and Allosteric regulation.
Her work in Sphingosine-1-phosphate tackles topics such as Signal transduction which are related to areas like Estrogen receptor.
Her study explores the link between Biochemistry and topics such as Phosphatidic acid that cross with problems in Phosphatase, Lysophosphatidic acid, Diacylglycerol kinase, Phospholipase D and PLCD3.
Her most cited work include:
- Sphingosine 1-phosphate signalling in mammalian cells (666 citations)
- Sphingosine 1-phosphate and cancer. (623 citations)
- International Union of Pharmacology. XXXIV. Lysophospholipid Receptor Nomenclature (431 citations)
What are the main themes of her work throughout her whole career to date?
Susan Pyne mainly focuses on Sphingosine, Cell biology, Sphingosine-1-phosphate, Biochemistry and Sphingosine kinase.
Her Sphingosine study incorporates themes from Lipid signaling, Cancer research and Kinase.
Her work deals with themes such as Protein structure and Ceramide, which intersect with Kinase.
Her study focuses on the intersection of Cell biology and fields such as Platelet-derived growth factor receptor with connections in the field of Receptor complex and Tyrosine phosphorylation.
Her biological study spans a wide range of topics, including Cancer cell, Endocrinology and Dihydroceramide desaturase.
Her Sphingosine kinase research is multidisciplinary, incorporating perspectives in Cancer, Pharmacology, Phosphorylation and p38 mitogen-activated protein kinases.
She most often published in these fields:
- Sphingosine (50.60%)
- Cell biology (44.64%)
- Sphingosine-1-phosphate (37.50%)
What were the highlights of her more recent work (between 2014-2021)?
- Sphingosine (50.60%)
- Sphingosine-1-phosphate (37.50%)
- Sphingosine kinase (33.93%)
In recent papers she was focusing on the following fields of study:
Her primary areas of study are Sphingosine, Sphingosine-1-phosphate, Sphingosine kinase, Kinase and Cell biology.
The study incorporates disciplines such as Cancer and Lipid signaling in addition to Sphingosine.
Susan Pyne interconnects Dihydroceramide desaturase, Ceramide, G protein-coupled receptor and Pharmacology in the investigation of issues within Sphingosine-1-phosphate.
Her work carried out in the field of Sphingosine kinase brings together such families of science as Cancer research, Cancer cell, Immunology, Phosphorylation and Sphingosine kinase 1.
Susan Pyne studies Protein kinase A, a branch of Kinase.
Her study in Cell biology is interdisciplinary in nature, drawing from both Amino acid and Protein structure.
Between 2014 and 2021, her most popular works were:
- Sphingosine 1-phosphate and sphingosine kinases in health and disease: Recent advances (106 citations)
- Role of sphingosine 1-phosphate receptors, sphingosine kinases and sphingosine in cancer and inflammation (97 citations)
- Proteasomal degradation of sphingosine kinase 1 and inhibition of dihydroceramide desaturase by the sphingosine kinase inhibitors, SKi or ABC294640, induces growth arrest in androgen-independent LNCaP-AI prostate cancer cells. (48 citations)
In her most recent research, the most cited papers focused on:
Susan Pyne focuses on Sphingosine, Sphingosine kinase, Sphingosine-1-phosphate, Cell biology and Kinase.
Her Sphingosine research is within the category of Receptor.
Her Sphingosine kinase research is multidisciplinary, incorporating elements of Cancer research, Lipid signaling, Sphingosine kinase 1 and SPHK2.
Her studies in Sphingosine-1-phosphate integrate themes in fields like Endocrinology and G protein-coupled receptor.
Susan Pyne combines subjects such as Cancer cell and Sphingosine-1-phosphate receptor with her study of Cell biology.
Her Biochemistry research incorporates themes from Prostate cancer and LNCaP.
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