David N. Brindley

Overview

Best Publications

• Three Mammalian Lipins Act as Phosphatidate Phosphatases with Distinct Tissue Expression Patterns

  Jimmy Donkor;Meltem Sariahmetoglu;Jay Dewald;David N. Brindley

  417
  Citations

• Possible connections between stress, diabetes, obesity, hypertension and altered lipoprotein metabolism that may result in atherosclerosis.

  David N. Brindley;Yves Rolland

  392
  Citations

• High-fat feeding alters both basal and stress-induced hypothalamic-pituitary-adrenal activity in the rat

  Beth M. Tannenbaum;David N. Brindley;Gloria S. Tannenbaum;Gloria S. Tannenbaum;Mary F. Dallman

  382
  Citations

• (n-3) PUFA Alter Raft Lipid Composition and Decrease Epidermal Growth Factor Receptor Levels in Lipid Rafts of Human Breast Cancer Cells

  Patricia D. Schley;David N. Brindley;Catherine J. Field

  364
  Citations

• Plasma membrane fractions from rat liver contain a phosphatidate phosphohydrolase distinct from that in the endoplasmic reticulum and cytosol.

  Z Jamal;A Martin;A Gomez-Muñoz;D N Brindley

  323
  Citations

• Lipid phosphate phosphatases and related proteins: signaling functions in development, cell division, and cancer.

  David N. Brindley

  307
  Citations

• Mammalian lipid phosphate phosphohydrolases.

  David N. Brindley;David W. Waggoner

  298
  Citations

• Sphingosine 1-phosphate released from platelets during clotting accounts for the potent endothelial cell chemotactic activity of blood serum and provides a novel link between hemostasis and angiogenesis.

  Denis English;Zachary Welch;A. Thomas Kovala;Kevin Harvey

  291
  Citations

• Intracellular translocation of phosphatidate phosphohydrolase and its possible role in the control of glycerolipid synthesis

  David N. Brindley

  283
  Citations

• Fatty acids promote translocation of CTP:phosphocholine cytidylyltransferase to the endoplasmic reticulum and stimulate rat hepatic phosphatidylcholine synthesis.

  S L Pelech;P H Pritchard;D N Brindley;D E Vance

  251
  Citations

• Lipid phosphate phosphatases and signaling

  David N. Brindley;Carlos Pilquil

  241
  Citations

• Studies on the fractionation of mucosal homogenates from the small intestine.

  G. Hübscher;Gwen R. West;D. N. Brindley

  241
  Citations

• Induction of endothelial cell chemotaxis by sphingosine 1-phosphate and stabilization of endothelial monolayer barrier function by lysophosphatidic acid, potential mediators of hematopoietic angiogenesis.

  Denis English;A. Thomas Kovala;Zachary Welch;Kevin A. Harvey

  240
  Citations

• Cell-permeable ceramides inhibit the stimulation of DNA synthesis and phospholipase D activity by phosphatidate and lysophosphatidate in rat fibroblasts.

  A Gomez-Muñoz;A Martin;L O'Brien;D N Brindley

  231
  Citations

• Thematic Review Series: Glycerolipids. Multiple roles for lipins/phosphatidate phosphatase enzymes in lipid metabolism *

  Karen Reue;David N. Brindley

  225
  Citations

• Platelet-released phospholipids link haemostasis and angiogenesis

  Denis English;Joe G.N. Garcia;D.N. Brindley

  217
  Citations

• Stress and lipoprotein metabolism: Modulators and mechanisms

  David N. Brindley;Barbara S. McCann;Raymond Niaura;Catherine M. Stoney

  209
  Citations

• Interaction of Ceramides, Sphingosine, and Sphingosine 1-Phosphate in Regulating DNA Synthesis and Phospholipase D Activity

  Antonio Gómez-Muñoz;David W. Waggoner;Lori O'Brien;David N. Brindley

  208
  Citations

• Phosphatidate phosphohydrolase catalyzes the hydrolysis of ceramide 1- phosphate, lysophosphatidate, and sphingosine 1-phosphate

  David W. Waggoner;Antonio Gómez-Muñoz;Jay Dewald;David N. Brindley

  194
  Citations

• Short-chain ceramide-1-phosphates are novel stimulators of DNA synthesis and cell division: antagonism by cell-permeable ceramides.

  A. Gomez-Munoz;P. A. Duffy;A. Martin;L. O'brien

  193
  Citations