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Michael A. Walter

Michael A. Walter

D-Index & Metrics

Genetics

D-Index
52
Citations
9383
World Ranking
3795
National Ranking
145

Overview

Michael A. Walter is affiliated with the University of Alberta in Canada. Their research spans fields primarily in Biochemistry, Genetics and Molecular Biology, with significant work also in Medicine. The scientist's subfields of study include Molecular Biology, Radiology, Nuclear Medicine and Imaging, Cell Biology, Ophthalmology, and Genetics.

Their research covers topics such as Retinal Development and Disorders, FOXO transcription factor regulation, Retinopathy of Prematurity Studies, Genomics and Chromatin Dynamics, DNA Repair Mechanisms, Genomics and Phylogenetic Studies, and Cellular transport and secretion.

Michael A. Walter has contributed to several scholarly publications including:

  • "FOXQ1 is Differentially Expressed Across Breast Cancer Subtypes with Low Expression Associated with Poor Overall Survival" (2021), published in Breast Cancer Targets and Therapy
  • "Functional Domains and Evolutionary History of the PMEL and GPNMB Family Proteins" (2021), published in Molecules
  • "Disrupting the Repeat Domain of Premelanosome Protein (PMEL) Produces Dysamyloidosis and Dystrophic Ocular Pigment Reflective of Pigmentary Glaucoma" (2023), published in International Journal of Molecular Sciences
  • "Ocular genetics in the genomics age" (2020), published in American Journal of Medical Genetics Part C Seminars in Medical Genetics
  • "The Explorer's Guide to Biology: A Free Multimedia Educational Resource to Promote Deep Learning and Understanding of the Scientific Process" (2022), published in Journal of Microbiology and Biology Education

Frequent publication venues for Michael A. Walter include:

  • American Journal of Medical Genetics Part C Seminars in Medical Genetics
  • Breast Cancer Targets and Therapy
  • Molecules
  • International Journal of Molecular Sciences
  • Journal of Microbiology and Biology Education

Repeated collaborations appear with coauthors including:

  • Tim Footz
  • Fahed Elian
  • Ubah Are
  • Paulo S Nuin
  • Todd McMullen

Through their work, Walter engages with both experimental and genomic aspects of molecular biology and medicine, contributing to the understanding of ocular genetics, pigment-related disorders, and broader molecular evolutionary studies. Their detailed study of proteins relevant to pigmentation and associated disorders intersects with ophthalmology and biochemistry fields, addressing complex genetic and cellular mechanisms.

Best Publications

  • Circular transcripts of the testis-determining gene Sry in adult mouse testis

    Blanche Capel;Amanda Swain;Silvia Nicolis;Adam Hacker

  • A method for constructing radiation hybrid maps of whole genomes

    Michael A. Walter;Dominique J. Spillett;Philip Thomas;Jean Weissenbach

  • The Forkhead/Winged Helix Gene Mf1 Is Disrupted in the Pleiotropic Mouse Mutation congenital hydrocephalus

    Tsutomu Kume;Ke Yu Deng;Virginia Winfrey;Douglas B. Gould

  • Mutations of the forkhead/winged-helix gene, FKHL7, in patients with Axenfeld-Rieger anomaly.

    Alan J. Mears;Tim Jordan;Farideh Mirzayans;Stéphane Dubois

  • FOXC1 is a potential prognostic biomarker with functional significance in basal-like breast cancer

    Partha S. Ray;Jinhua Wang;Ying Qu;Myung Shin Sim

  • ROLES FOR THE WINGED HELIX TRANSCRIPTION FACTORS MF1 AND MFH1 IN CARDIOVASCULAR DEVELOPMENT REVEALED BY NONALLELIC NONCOMPLEMENTATION OF NULL ALLELES

    Glenn E. Winnier;Tsutomu Kume;Keyu Deng;Rhonda Rogers

  • Loss of mitochondrial peptidase Clpp leads to infertility, hearing loss plus growth retardation via accumulation of CLPX, mtDNA and inflammatory factors

    Suzana Gispert;Dajana Parganlija;Michael Klinkenberg;Stefan Dröse

  • Molecular genetics of Axenfeld–Rieger malformations

    Matthew A. Lines;Kathy Kozlowski;Michael A. Walter

  • Mutation of the PAX6 gene in patients with autosomal dominant keratitis.

    F Mirzayans;W G Pearce;I M MacDonald;M A Walter

  • Genotype-phenotype correlations in Axenfeld-Rieger malformation and glaucoma patients with FOXC1 and PITX2 mutations.

    M. Hermina Strungaru;Irina Dinu;Michael A. Walter

  • Mutation of the bone morphogenetic protein GDF3 causes ocular and skeletal anomalies

    Ming Ye;Karyn M. Berry-Wynne;Mika Asai-Coakwell;Periasamy Sundaresan

  • Functional interactions between FOXC1 and PITX2 underlie the sensitivity to FOXC1 gene dose in Axenfeld–Rieger syndrome and anterior segment dysgenesis

    Fred B. Berry;Matthew A. Lines;J. Martin Oas;Tim Footz

  • Mutation in the RIEG1 Gene in Patients with Iridogoniodysgenesis Syndrome

    Stephen C. Kulak;Kathy Kozlowski;Elena V. Semina;William G. Pearce

  • SOX Genes: Architects of Development

    Heather M. Prior;Michael A. Walter

  • Variation in residual PITX2 activity underlies the phenotypic spectrum of anterior segment developmental disorders

    Kathy Kozlowski;Michael A. Walter

  • Axenfeld-Rieger syndrome.

    Morteza Seifi;Michael A Walter

  • Axenfeld-Rieger syndrome resulting from mutation of the FKHL7 gene on chromosome 6p25

    Farideh Mirzayans;Douglas B Gould;E Héon;Gail D Billingsley

  • Analyses of the Effects That Disease-Causing Missense Mutations Have on the Structure and Function of the Winged-Helix Protein FOXC1

    Ramsey A. Saleem;Sharmila Banerjee-Basu;Fred B. Berry;Andreas D. Baxevanis

  • Complete physical map of the human immunoglobulin heavy chain constant region gene complex

    Marten H. Hofker;Michael A. Walter;Diane W. Cox

  • Genotype–Phenotype Correlation in Axenfeld–Rieger Malformation (ARM) and Glaucoma Patients With FOXC1 and PITX2 Mutations

    M.H. Strungaru;M.A. Walter

Frequent Co-Authors

Jane C. Sowden
Jane C. Sowden University College London
Robert Ritch
Robert Ritch New York Eye and Ear Infirmary
Shomi S. Bhattacharya
Shomi S. Bhattacharya University College London
Peng T. Khaw
Peng T. Khaw University College London
Elise Héon
Elise Héon University of Toronto
Elena V. Semina
Elena V. Semina Medical College of Wisconsin
Andreas D. Baxevanis
Andreas D. Baxevanis National Institutes of Health
Sue Povey
Sue Povey University College London
Janey L. Wiggs
Janey L. Wiggs Massachusetts Eye and Ear Infirmary

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