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Sarah E. Bergen

Sarah E. Bergen

D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
39516
World Ranking
13494
National Ranking
201

Overview

Sarah E. Bergen is affiliated with the Karolinska Institute in Sweden. Their research spans several interconnected fields, predominantly within biochemistry, genetics, molecular biology, and medicine. The main subfields of study include genetics, psychiatry and mental health, molecular biology, clinical psychology, and speech and hearing.

The scientist's work covers a range of core topics that include genetic associations and epidemiology, bipolar disorder and treatment, adolescent and pediatric healthcare, schizophrenia research and treatment, genomics and rare diseases, bioinformatics and genomic networks, as well as eating disorders and behaviors.

Sarah E. Bergen has authored multiple papers, with some of the most recent publications listed below:

  • Mapping genomic loci implicates genes and synaptic biology in schizophrenia (2022), published in Nature
  • Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology (2021), published in Nature Genetics
  • Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals (2020), published in Nature Metabolism
  • Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets (2023), published in Nature Immunology
  • A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts (2021), published in Biological Psychiatry

Throughout their career, Bergen has collaborated frequently with several co-authors. Notable frequent co-authors include:

  • Paul Lichtenstein
  • Alexander Ploner
  • Mikael Landén
  • Ralf Kuja-Halkola
  • Patrick F. Sullivan

The preferred venues for publishing include journals and platforms such as:

  • UNC Libraries
  • European Neuropsychopharmacology
  • Translational Psychiatry
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Psychiatry

Sarah E. Bergen's research contributions are largely concentrated on deciphering the genetic architecture underlying psychiatric disorders and related biological processes. Their studies integrate large cohort analyses and genomic evaluations, investigating diseases like schizophrenia and bipolar disorder, as well as exploring the genetic basis of cardiovascular and immune-mediated conditions. The scope and interdisciplinary nature of their work align with emerging trends in genomics and psychiatric genetics, feeding into potential clinical applications and therapeutic target discovery.

Best Publications

  • Biological insights from 108 schizophrenia-associated genetic loci

    Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Aiden Corvin;James T. R. Walters

  • Genome-wide association study identifies five new schizophrenia loci

    Stephan Ripke;Alan R. Sanders;Kenneth S. Kendler;Douglas F. Levinson

  • Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

    S. Hong Lee;Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Stephen V. Faraone

  • Analysis of shared heritability in common disorders of the brain

    Verneri Anttila;Verneri Anttila;Brendan Bulik-Sullivan;Brendan Bulik-Sullivan;Hilary K. Finucane;Raymond K. Walters;Raymond K. Walters

  • Genome-wide association analysis identifies 13 new risk loci for schizophrenia

    Stephan Ripke;Stephan Ripke;Colm T. O'Dushlaine;Kimberly D. Chambert;Jennifer L. Moran

  • Genome-wide association study identifies 30 loci associated with bipolar disorder

    Eli A. Stahl;Eli A. Stahl;Gerome Breen;Andreas J. Forstner;Andrew McQuillin

  • A polygenic burden of rare disruptive mutations in schizophrenia

    Shaun M Purcell;Jennifer L Moran;Menachem Fromer;Douglas Ruderfer

  • Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

    Pamela Sklar;Pamela Sklar;Stephan Ripke;Stephan Ripke;Laura J. Scott;Ole A. Andreassen

  • Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

    Bjarni J. Vilhjálmsson;Jian Yang;Hilary K. Finucane;Alexander Gusev

  • Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

    Niamh Mullins;Andreas J. Forstner;Andreas J. Forstner;Andreas J. Forstner;Kevin S. O'Connell;Kevin S. O'Connell;Brandon Coombes

  • Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

    Phil H. Lee;Verneri Anttila;Hyejung Won;Yen-Chen A. Feng

  • Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

    Christian R Marshall;Daniel P Howrigan;Daniel P Howrigan;Daniele Merico;Bhooma Thiruvahindrapuram

  • Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

    Douglas M. Ruderfer;Stephan Ripke;Stephan Ripke;Stephan Ripke;Andrew McQuillin;James Boocock

  • Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

    Colm O'Dushlaine;Lizzy Rossin;Phil H. Lee;Laramie Duncan;Laramie Duncan

  • Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases

    Alexander Gusev;S. Hong Lee;Gosia Trynka;Hilary Finucane

  • Discovery and Statistical Genotyping of Copy-Number Variation from Whole-Exome Sequencing Depth

    Menachem Fromer;Jennifer L. Moran;Kimberly Chambert;Eric Banks

  • Age-Related Changes in Heritability of Behavioral Phenotypes Over Adolescence and Young Adulthood: A Meta-Analysis

    Sarah E Bergen;Charles O Gardner;Kenneth S Kendler

  • Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals

    Lasse Folkersen;Stefan Gustafsson;Qin Wang;Qin Wang;Daniel Hvidberg Hansen

  • Copy number variants in schizophrenia: confirmation of five previous findings and new evidence for 3q29 microdeletions and VIPR2 duplications.

    Douglas F. Levinson;Jubao Duan;Sang Oh;Kai Wang

  • Relationship of Brain-Derived Neurotrophic Factor and Its Receptor TrkB to Altered Inhibitory Prefrontal Circuitry in Schizophrenia

    Takanori Hashimoto;Sarah E. Bergen;Quyen L. Nguyen;Baoji Xu

Frequent Co-Authors

Mikael Landén
Mikael Landén University of Gothenburg
Patrick F. Sullivan
Patrick F. Sullivan University of North Carolina at Chapel Hill
Shaun Purcell
Shaun Purcell Harvard Medical School
Christina M. Hultman
Christina M. Hultman Karolinska Institute
Douglas M. Ruderfer
Douglas M. Ruderfer Vanderbilt University Medical Center
Stephan Ripke
Stephan Ripke Massachusetts General Hospital
Thomas G. Schulze
Thomas G. Schulze Ludwig-Maximilians-Universität München
Pamela Sklar
Pamela Sklar Icahn School of Medicine at Mount Sinai
Jordan W. Smoller
Jordan W. Smoller Harvard University
Stefan Herms
Stefan Herms University of Basel

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