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Genetics

D-Index
82
Citations
70596
World Ranking
1436
National Ranking
675

Overview

Douglas M. Ruderfer is affiliated with Vanderbilt University Medical Center in the United States. Their research primarily spans the fields of biochemistry, genetics, and molecular biology. Within these broader categories, they have focused on genetics, molecular biology, clinical psychology, psychiatry and mental health, and experimental and cognitive psychology.

The main topics covered in Douglas M. Ruderfer's research include genetic associations and epidemiology, genomics and rare diseases, suicide and self-harm studies, bioinformatics and genomic networks, genetics and neurodevelopmental disorders, gene expression and cancer classification, and genomic variations and chromosomal abnormalities.

Douglas M. Ruderfer has contributed frequently to several publication venues. These include bioRxiv (Cold Spring Harbor Laboratory), UNC Libraries, European Neuropsychopharmacology, Molecular Psychiatry, and Brain. Their significant body of work in these journals indicates active participation in both preprint and peer-reviewed scientific communication.

Frequent coauthors working with Douglas M. Ruderfer include Theodore Morley, Niamh Mullins, Lide Han, Jordan W. Smoller, and Pamela Sklar, with collaborative works numbering from 16 to 24 publications for these individuals, reflecting sustained research partnerships.

Some recent papers authored by Douglas M. Ruderfer and collaborators are:

  • Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions, 2020, Scientific Data
  • A cross-disorder dosage sensitivity map of the human genome, 2022, Cell
  • Genetic variants and functional pathways associated with resilience to Alzheimer's disease, 2020, Brain
  • Clinical laboratory test-wide association scan of polygenic scores identifies biomarkers of complex disease, 2021, Genome Medicine
  • Sleep patterns and risk of chronic disease as measured by long-term monitoring with commercial wearable devices in the All of Us Research Program, 2024, Nature Medicine

Best Publications

  • Analysis of protein-coding genetic variation in 60,706 humans

    Monkol Lek;Konrad J. Karczewski;Konrad J. Karczewski;Eric V. Minikel;Eric V. Minikel;Kaitlin E. Samocha

  • Biological insights from 108 schizophrenia-associated genetic loci

    Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Aiden Corvin;James T. R. Walters

  • Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

    Shaun M. Purcell;Shaun M. Purcell;Naomi R. Wray;Jennifer L. Stone;Jennifer L. Stone;Peter M. Visscher

  • Genome-wide association study identifies five new schizophrenia loci

    Stephan Ripke;Alan R. Sanders;Kenneth S. Kendler;Douglas F. Levinson

  • Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

    S. Hong Lee;Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Stephen V. Faraone

  • Association between Microdeletion and Microduplication at 16p11.2 and Autism

    Lauren A. Weiss;Yiping Shen;Joshua M. Korn;Joshua M. Korn;Dan E. Arking

  • De novo mutations in schizophrenia implicate synaptic networks

    Menachem Fromer;Andrew Pocklington;David Kavanagh;Hywel John Williams

  • Genome-wide association analysis identifies 13 new risk loci for schizophrenia

    Stephan Ripke;Stephan Ripke;Colm T. O'Dushlaine;Kimberly D. Chambert;Jennifer L. Moran

  • Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection

    Antonio F. Pardiñas;Peter Holmans;Andrew J. Pocklington;Valentina Escott-Price

  • Genome-wide association study identifies 30 loci associated with bipolar disorder

    Eli A. Stahl;Eli A. Stahl;Gerome Breen;Andreas J. Forstner;Andrew McQuillin

  • A polygenic burden of rare disruptive mutations in schizophrenia

    Shaun M Purcell;Jennifer L Moran;Menachem Fromer;Douglas Ruderfer

  • Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

    Pamela Sklar;Pamela Sklar;Stephan Ripke;Stephan Ripke;Laura J. Scott;Ole A. Andreassen

  • Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

    Bjarni J. Vilhjálmsson;Jian Yang;Hilary K. Finucane;Alexander Gusev

  • Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

    Niamh Mullins;Andreas J. Forstner;Andreas J. Forstner;Andreas J. Forstner;Kevin S. O'Connell;Kevin S. O'Connell;Brandon Coombes

  • Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder

    Manuel A R Ferreira;Michael C O'Donovan;Yan A Meng;Ian R Jones

  • Rare chromosomal deletions and duplications increase risk of schizophrenia

    Jennifer L. Stone;Jennifer L. Stone;Jennifer L. Stone;Michael C. O’Donovan;Hugh Gurling;George K. Kirov

  • Gene expression elucidates functional impact of polygenic risk for schizophrenia

    Menachem Fromer;Panos Roussos;Solveig K. Sieberts;Jessica S. Johnson

  • Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

    Christian R Marshall;Daniel P Howrigan;Daniel P Howrigan;Daniele Merico;Bhooma Thiruvahindrapuram

  • Association between microdeletion and microduplication at 16p11.2 and autism

    Lauren A. Weiss;Yiping Shen;Joshua M. Korn;Dan E. Arking

  • De Novo CNV Analysis Implicates Specific Abnormalities of Postsynaptic Signalling Complexes in the Pathogenesis of Schizophrenia

    George Kirov;Andrew Pocklington;Peter Alan Holmans;Dobril Ivanov

Frequent Co-Authors

Shaun Purcell
Shaun Purcell Harvard Medical School
Pamela Sklar
Pamela Sklar Icahn School of Medicine at Mount Sinai
Eli A. Stahl
Eli A. Stahl Icahn School of Medicine at Mount Sinai
Stephan Ripke
Stephan Ripke Massachusetts General Hospital
Patrick F. Sullivan
Patrick F. Sullivan University of North Carolina at Chapel Hill
Jordan W. Smoller
Jordan W. Smoller Harvard University
Menachem Fromer
Menachem Fromer Broad Institute
Sarah E. Bergen
Sarah E. Bergen Karolinska Institute
Michael Conlon O'Donovan
Michael Conlon O'Donovan Cardiff University
Michael John Owen
Michael John Owen Cardiff University

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