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Molecular Biology

D-Index
120
Citations
54671
World Ranking
259
National Ranking
151

Research.com Recognitions

  • 2008 - Fellow of the American Academy of Arts and Sciences
  • 2005 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2000 - Member of the National Academy of Sciences

Overview

Bruce Stillman is affiliated with Cold Spring Harbor Laboratory in the United States. Their research primarily spans the field of Biochemistry, Genetics, and Molecular Biology, with a focus on Molecular Biology, Genetics, Cell Biology, Oncology, and Food Science as subfields.

The scientist's work addresses several main topics including DNA Repair Mechanisms, Genomics and Chromatin Dynamics, CRISPR and Genetic Engineering, Bacterial Genetics and Biotechnology, Microtubule and Mitosis Dynamics, Cancer-related Molecular Pathways, and DNA and Nucleic Acid Chemistry.

Selected recent papers authored or co-authored by Bruce Stillman include the following:

  • Origins of DNA replication in eukaryotes (2023), published in Molecular Cell
  • The structure of ORC-Cdc6 on an origin DNA reveals the mechanism of ORC activation by the replication initiator Cdc6 (2021), published in Nature Communications
  • Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6 (2020), published in Proceedings of the National Academy of Sciences
  • Multiple, short protein binding motifs in ORC1 and CDC6 control the initiation of DNA replication (2021), published in Molecular Cell
  • Evolution of DNA replication origin specification and gene silencing mechanisms (2020), published in Nature Communications

Frequent co-authors collaborating with Bruce Stillman include Christian Speck, Huilin Li, Yi-Jun Sheu, Leemor Joshua-Tor, and Narges Zali.

Publications appear regularly in venues such as bioRxiv (Cold Spring Harbor Laboratory), eLife, Molecular Cell, Nature Communications, and Proceedings of the National Academy of Sciences.

Bruce Stillman has received several recognitions, including Fellowship of the American Academy of Arts and Sciences awarded in 2008, Fellowship of the American Association for the Advancement of Science (AAAS) in 2005, and membership in the National Academy of Sciences since 2000.

Best Publications

  • The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

    Shou Waga;Gregory J. Hannon;David Beach;Bruce Stillman

  • ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex.

    Stephen P. Bell;Bruce Stillman

  • Cold Spring Harbor Laboratory

    Bruce Stillman

  • Functional identity of proliferating cell nuclear antigen and a DNA polymerase-δ auxiliary protein

    Gregory Prelich;Cheng-Keat Tan;Matthew Kostura;Michael B. Mathews

  • Chromatin Association of Human Origin Recognition Complex, Cdc6, and Minichromosome Maintenance Proteins during the Cell Cycle: Assembly of Prereplication Complexes in Late Mitosis

    Juan Méndez;Bruce Stillman

  • THE DNA REPLICATION FORK IN EUKARYOTIC CELLS

    Shou Waga;Bruce Stillman

  • Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair

    Rong Li;Shou Waga;Gregory J. Hannon;David Beach

  • Replication-dependent marking of DNA by PCNA facilitates CAF-1-coupled inheritance of chromatin.

    Kei-ichi Shibahara;Bruce Stillman

  • Purification and characterization of CAF-I, a human cell factor required for chromatin assembly during DNA replication in vitro

    Susan Smith;Bruce Stillman

  • A yeast chromosomal origin of DNA replication defined by multiple functional elements

    York Marahrens;York Marahrens;Bruce Stillman

  • Nucleosome assembly by a complex of CAF-1 and acetylated histones H3/H4.

    Alain Verreault;Paul D Kaufman;Ryuji Kobayashi;Bruce Stillman

  • The knockout mouse project

    Christopher P. Austin;James F. Battey;Allan Bradley;Maja Bucan

  • Anatomy of a DNA replication fork revealed by reconstitution of SV40 DNA replication in vitro

    Shou Waga;Bruce Stillman

  • Inhibition of CDK activity and PCNA-dependent DNA replication by p21 is blocked by interaction with the HPV-16 E7 oncoprotein

    Jens Oliver Funk;Shou Waga;Jo Beth Harry;Erik Espling

  • Cell Cycle Control of DNA Replication

    Bruce Stillman

  • A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication

    Cecile Evrin;Pippa Clarke;Juergen Zech;Rudi Lurz

  • The cell-cycle regulated proliferating cell nuclear antigen is required for SV40 DNA replication in vitro.

    Gregory Prelich;Matthew Kostura;Daniel R. Marshak;Michael B. Mathews

  • Initiation of eukaryotic DNA replication in vitro

    Bruce Stillman

  • FASCIATA genes for chromatin assembly factor-1 in arabidopsis maintain the cellular organization of apical meristems.

    Hidetaka Kaya;Kei-ichi Shibahara;Ken-ichiro Taoka;Masaki Iwabuchi

  • Replication and supercoiling of simian virus 40 DNA in cell extracts from human cells.

    B W Stillman;Y Gluzman

Frequent Co-Authors

Huilin Li
Huilin Li Van Andel Institute
Leemor Joshua-Tor
Leemor Joshua-Tor Cold Spring Harbor Laboratory
John F. X. Diffley
John F. X. Diffley The Francis Crick Institute
Ryuji Kobayashi
Ryuji Kobayashi The University of Texas MD Anderson Cancer Center
Toshiki Tsurimoto
Toshiki Tsurimoto Kyushu University
Fuyuhiko Tamanoi
Fuyuhiko Tamanoi Kyoto University
Paul D. Kaufman
Paul D. Kaufman University of Massachusetts Chan Medical School
Thomas J. Kelly
Thomas J. Kelly Memorial Sloan Kettering Cancer Center
Michael B. Mathews
Michael B. Mathews Rutgers, The State University of New Jersey

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