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Molecular Biology

D-Index
82
Citations
25530
World Ranking
935
National Ranking
69

John F. X. Diffley publication distribution in Molecular Biology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Molecular Biology in 2026. The highlighted bar marks where John F. X. Diffley sits on this spectrum.

47–56 publications: 7 scientists 57–66 publications: 17 scientists 67–76 publications: 65 scientists 77–86 publications: 90 scientists 87–96 publications: 125 scientists 97–106 publications: 131 scientists 107–116 publications: 162 scientists 117–126 publications: 177 scientists 127–136 publications: 158 scientists 137–146 publications: 158 scientists 147–156 publications: 146 scientists 157–166 publications: 159 scientists 167–176 publications: 131 scientists 177–186 publications: 110 scientists 187–196 publications: 112 scientists 197–206 publications: 100 scientists 207–216 publications: 89 scientists 217–226 publications: 98 scientists 227–236 publications: 74 scientists 237–246 publications: 72 scientists 247–256 publications: 63 scientists 257–266 publications: 53 scientists 267–276 publications: 54 scientists 277–286 publications: 49 scientists 287–296 publications: 52 scientists 297–306 publications: 43 scientists 307–316 publications: 46 scientists 317–326 publications: 41 scientists 327–336 publications: 42 scientists 337–346 publications: 31 scientists 347–356 publications: 28 scientists 357–366 publications: 29 scientists 367–376 publications: 26 scientists 377–386 publications: 24 scientists 387–396 publications: 24 scientists 397–406 publications: 14 scientists 407–416 publications: 13 scientists 417–426 publications: 20 scientists 427–436 publications: 12 scientists 437–446 publications: 20 scientists 447–456 publications: 11 scientists 457–466 publications: 10 scientists 467–476 publications: 14 scientists 477–486 publications: 14 scientists 487–496 publications: 10 scientists 497–506 publications: 13 scientists 507–516 publications: 13 scientists 517–526 publications: 2 scientists 527–536 publications: 4 scientists 537–546 publications: 6 scientists 547–556 publications: 8 scientists 557–563 publications: 6 scientists 564+ publications: 100 scientists
47 publications 564+

This scientist: 165 publications — 45th percentile

45% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 564 publications or more.

John F. X. Diffley D-index placement in Molecular Biology in 2026

The chart shows the D-index (discipline H-index) distribution of Molecular Biology scientists ranked by Research.com in 2026. The highlighted bar marks where John F. X. Diffley sits on this spectrum.

40–41 D-Index: 36 scientists 42–43 D-Index: 101 scientists 44–45 D-Index: 115 scientists 46–47 D-Index: 121 scientists 48–49 D-Index: 118 scientists 50–51 D-Index: 130 scientists 52–53 D-Index: 106 scientists 54–55 D-Index: 116 scientists 56–57 D-Index: 113 scientists 58–59 D-Index: 129 scientists 60–61 D-Index: 120 scientists 62–63 D-Index: 105 scientists 64–65 D-Index: 131 scientists 66–67 D-Index: 95 scientists 68–69 D-Index: 97 scientists 70–71 D-Index: 106 scientists 72–73 D-Index: 83 scientists 74–75 D-Index: 89 scientists 76–77 D-Index: 77 scientists 78–79 D-Index: 70 scientists 80–81 D-Index: 73 scientists 82–83 D-Index: 60 scientists 84–85 D-Index: 48 scientists 86–87 D-Index: 45 scientists 88–89 D-Index: 50 scientists 90–91 D-Index: 31 scientists 92–93 D-Index: 51 scientists 94–95 D-Index: 43 scientists 96–97 D-Index: 38 scientists 98–99 D-Index: 39 scientists 100–101 D-Index: 41 scientists 102–103 D-Index: 29 scientists 104–105 D-Index: 33 scientists 106–107 D-Index: 35 scientists 108–109 D-Index: 20 scientists 110–111 D-Index: 38 scientists 112–113 D-Index: 19 scientists 114–115 D-Index: 28 scientists 116–117 D-Index: 13 scientists 118–119 D-Index: 23 scientists 120–121 D-Index: 16 scientists 122–123 D-Index: 15 scientists 124–125 D-Index: 11 scientists 126–127 D-Index: 21 scientists 128–129 D-Index: 7 scientists 130–131 D-Index: 13 scientists 132–133 D-Index: 14 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 9 scientists 138–139 D-Index: 8 scientists 140–141 D-Index: 16 scientists 142–143 D-Index: 7 scientists 144 D-Index: 7 scientists 145+ D-Index: 100 scientists
40 D-Index 145+

This scientist: 82 D-Index — 70th percentile

70% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 145 D-Index or more.

Research.com Recognitions

  • 2020 - Member of the National Academy of Sciences
  • 2019 - Canada Gairdner International Award
  • 2009 - Member of Academia Europaea
  • 2007 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2005 - Fellow of the Royal Society, United Kingdom
  • 2003 - Paul Marks Prize for Cancer Research, Memorial Sloan Kettering Cancer Center
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)

Overview

John F. X. Diffley is affiliated with The Francis Crick Institute in the United Kingdom. Their research spans multiple domains within biochemistry, genetics, and molecular biology, with particular focus on molecular biology, infectious diseases, genetics, cell biology, and oncology.

The scientist has contributed extensively to topics including DNA repair mechanisms, genomics and chromatin dynamics, research on SARS-CoV-2 and COVID-19, bacterial genetics and biotechnology, microtubule and mitosis dynamics, DNA and nucleic acid chemistry, and viral gastroenteritis research and epidemiology.

Key recent publications include:

  • The Initiation of Eukaryotic DNA Replication, 2022, Annual Review of Biochemistry
  • Cyclin E-induced replicative stress drives p53-dependent whole-genome duplication, 2023, Cell
  • Mechanism of replication origin melting nucleated by CMG helicase assembly, 2022, Nature
  • Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp13 helicase, 2021, Biochemical Journal
  • Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp15 endoribonuclease, 2021, Biochemical Journal

The scientist's frequent co-authors include Berta Canal, Florian Weissmann, Lucy S. Drury, Jingkun Zeng, and Rachel Ulferts.

John F. X. Diffley has published often in venues such as bioRxiv (Cold Spring Harbor Laboratory), Biochemical Journal, Nature Structural & Molecular Biology, Cell, and Nature Communications.

The scientist has received several awards, including:

  • Member of the National Academy of Sciences, 2020
  • Canada Gairdner International Award, 2019
  • Member of Academia Europaea, 2009
  • Fellow of the American Association for the Advancement of Science (AAAS), 2007
  • Fellow of the Royal Society, United Kingdom, 2005
  • Paul Marks Prize for Cancer Research, Memorial Sloan Kettering Cancer Center, 2003
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom

Best Publications

  • A Mec1- and Rad53-dependent checkpoint controls late-firing origins of DNA replication

    Corrado Santocanale;John F. X. Diffley

  • Regulation of DNA replication fork progression through damaged DNA by the Mec1/Rad53 checkpoint

    José Antonio Tercero;John F. X. Diffley

  • Concerted Loading of Mcm2-7 Double Hexamers Around DNA during DNA Replication Origin Licensing

    Dirk Remus;Fabienne Beuron;Gökhan Tolun;Jack D. Griffith

  • Uninterrupted MCM2-7 Function Required for DNA Replication Fork Progression

    Karim Labib;José Antonio Tercero;John F. X. Diffley

  • Two steps in the assembly of complexes at yeast replication origins in vivo

    John F.X. Diffley;Julie H. Cocker;Simon J. Dowell;Adele Rowley

  • Cdc6p-dependent loading of Mcm proteins onto pre-replicative chromatin in budding yeast

    Shane Donovan;Janet Harwood;Lucy S. Drury;John F. X. Diffley

  • Mrc1 transduces signals of DNA replication stress to activate Rad53.

    Annette A. Alcasabas;Alexander J. Osborn;Jeff Bachant;Jeff Bachant;Fenghua Hu

  • Phosphorylation of Sld2 and Sld3 by cyclin-dependent kinases promotes DNA replication in budding yeast

    Philip Zegerman;John F. X. Diffley

  • Regulation of Early Events in Chromosome Replication

    John F.X. Diffley

  • Regulated eukaryotic DNA replication origin firing with purified proteins

    Joseph T P Yeeles;Tom D Deegan;Agnieszka Janska;Anne Early

  • A Central Role for DNA Replication Forks in Checkpoint Activation and Response

    José Antonio Tercero;Maria Pia Longhese;John F.X Diffley

  • S-phase-promoting cyclin-dependent kinases prevent re-replication by inhibiting the transition of replication origins to a pre-replicative state.

    Christian Dahmann;John F.X. Diffley;Kim A. Nasmyth

  • Protein-DNA interactions at a yeast replication origin.

    John F. X. Diffley;Julie H. Cocker

  • An essential role for the Cdc6 protein in forming the pre-replicative complexes of budding yeast

    Julie H. Cocker;Simonetta Piatti;Corrado Santocanale;Kim Nasmyth

  • CDKs Promote DNA Replication Origin Licensing in Human Cells by Protecting Cdc6 from APC/C-Dependent Proteolysis

    Niels Mailand;John F.X. Diffley

  • The Cdc4/34/53 pathway targets Cdc6p for proteolysis in budding yeast

    Lucy S. Drury;Gordon Perkins;John F.X. Diffley

  • A close relative of the nuclear, chromosomal high-mobility group protein HMG1 in yeast mitochondria

    J.F.X. Diffley;B. Stillman

  • Interdependent nuclear accumulation of budding yeast Cdt1 and Mcm2-7 during G1 phase.

    Seiji Tanaka;John F.X. Diffley

  • The Cdc7 protein kinase is required for origin firing during S phase

    Kristine Bousset;John F.X. Diffley

  • DNA Replication and Oncogene-Induced Replicative Stress

    Stephanie A. Hills;John F.X. Diffley

Frequent Co-Authors

Bruce Stillman
Bruce Stillman Cold Spring Harbor Laboratory
Karim Labib
Karim Labib University of Dundee
Michael Howell
Michael Howell The Francis Crick Institute
Kim Nasmyth
Kim Nasmyth University of Oxford
Chris P. Ponting
Chris P. Ponting University of Edinburgh
Jack D. Griffith
Jack D. Griffith University of North Carolina at Chapel Hill
Wolfgang Hammerschmidt
Wolfgang Hammerschmidt Ludwig-Maximilians-Universität München
Antony M. Carr
Antony M. Carr University of Sussex
James E. Haber
James E. Haber Brandeis University
Stephen J. Elledge
Stephen J. Elledge Harvard University

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