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Microbiology

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54
Citations
9990
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3974
National Ranking
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Overview

Oscar Zaragoza is affiliated with the Instituto de Salud Carlos III in Spain and has contributed extensively to the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research focuses primarily on infectious diseases, with significant work in antifungal resistance and susceptibility, fungal infections and studies, as well as related subfields such as epidemiology, molecular biology, cell biology, and pulmonary and respiratory medicine.

The scientist's main research topics include:

  • Antifungal resistance and susceptibility
  • Fungal infections and studies
  • Plant pathogens and fungal diseases
  • Nail diseases and treatments
  • Plant-microbe interactions and immunity
  • Oral health in cancer treatment
  • Cytomegalovirus and herpesvirus research

Oscar Zaragoza's publication record includes articles in notable venues such as bioRxiv (Cold Spring Harbor Laboratory), Journal of Fungi, Microbiology Spectrum, Antimicrobial Agents and Chemotherapy, and Open Forum Infectious Diseases. Their recent papers include:

  • Population genomics of the pathogenic yeast Candida tropicalis identifies hybrid isolates in environmental samples (2021, PLoS Pathogens)
  • Global Emergence of Resistance to Fluconazole and Voriconazole in Candida parapsilosis in Tertiary Hospitals in Spain During the COVID-19 Pandemic (2022, Open Forum Infectious Diseases)
  • Identification of Off-Patent Drugs That Show Synergism with Amphotericin B or That Present Antifungal Action against Cryptococcus neoformans and Candida spp (2020, Antimicrobial Agents and Chemotherapy)
  • Adaptation of the emerging pathogenic yeast Candida auris to high caspofungin concentrations correlates with cell wall changes (2021, Virulence)
  • Human IgM Inhibits the Formation of Titan-Like Cells in Cryptococcus neoformans (2020, Infection and Immunity)

The scientist has collaborated frequently with a number of coauthors, including:

  • Nuria Trevijano-Contador
  • Irene García-Barbazán
  • Rocío García-Rodas
  • Suélen Andreia Rossi
  • Alba Torres-Cano

Oscar Zaragoza has also contributed to book publications, notably with a work published by Universidad de Guadalajara eBooks titled Marca de agua. Experiencias de escritores en torno a la lectura (2024).

Best Publications

  • The capsule of the fungal pathogen Cryptococcus neoformans

    Oscar Zaragoza;Marcio L. Rodrigues;Magdia De Jesus;Susana Frases

  • Vesicular Polysaccharide Export in Cryptococcus neoformans Is a Eukaryotic Solution to the Problem of Fungal Trans-Cell Wall Transport

    Marcio L. Rodrigues;Leonardo Nimrichter;Débora L. Oliveira;Susana Frases

  • Fungal cell gigantism during mammalian infection.

    Oscar Zaragoza;Oscar Zaragoza;Rocío García-Rodas;Joshua D. Nosanchuk;Manuel Cuenca-Estrella

  • It only takes one to do many jobs: Amphotericin B as antifungal and immunomodulatory drug.

    Ana Cecilia Mesa-Arango;Ana Cecilia Mesa-Arango;Liliana Scorzoni;Liliana Scorzoni;Oscar Zaragoza

  • Epidemiology and predictive factors for early and late mortality in Candida bloodstream infections: a population-based surveillance in Spain

    M. Puig-Asensio;B. Padilla;B. Padilla;J. Garnacho-Montero;O. Zaragoza

  • Experimental modulation of capsule size in Cryptococcus neoformans

    Oscar Zaragoza;Arturo Casadevall

  • Capsule enlargement in Cryptococcus neoformans confers resistance to oxidative stress suggesting a mechanism for intracellular survival

    Oscar Zaragoza;Cara J. Chrisman;Maria Victoria Castelli;Susana Frases

  • Protective role of trehalose during severe oxidative stress caused by hydrogen peroxide and the adaptive oxidative stress response in Candida albicans.

    Francisco J. Alvarez-Peral;Oscar Zaragoza;Yolanda Pedreno;Juan-Carlos Argüelles

  • Titan cells in Cryptococcus neoformans: cells with a giant impact.

    Oscar Zaragoza;Kirsten Nielsen

  • Basic principles of the virulence of Cryptococcus

    Oscar Zaragoza

  • The Production of Reactive Oxygen Species Is a Universal Action Mechanism of Amphotericin B against Pathogenic Yeasts and Contributes to the Fungicidal Effect of This Drug

    Ana Cecilia Mesa-Arango;Nuria Trevijano-Contador;Elvira Román;Ruth Sánchez-Fresneda

  • Induction of capsule growth in Cryptococcus neoformans by mammalian serum and CO(2).

    Oscar Zaragoza;Bettina C. Fries;Arturo Casadevall

  • Disruption of the Candida albicans TPS1 gene encoding trehalose-6-phosphate synthase impairs formation of hyphae and decreases infectivity.

    Oscar Zaragoza;Miguel Ángel Blázquez;Carlos Gancedo

  • More Is Not Necessarily Better: Prozone-Like Effects in Passive Immunization with IgG

    Carlos P. Taborda;Johanna Rivera;Oscar Zaragoza;Arturo Casadevall

  • Antifungal efficacy during Candida krusei infection in non-conventional models correlates with the yeast in vitro susceptibility profile.

    Liliana Scorzoni;Liliana Scorzoni;Maria Pilar de Lucas;Ana Cecilia Mesa-Arango;Ana Cecilia Mesa-Arango;Ana Marisa Fusco-Almeida

  • The non-mammalian host Galleria mellonella can be used to study the virulence of the fungal pathogen Candida tropicalis and the efficacy of antifungal drugs during infection by this pathogenic yeast

    Ana Cecilia Mesa-Arango;Ana Cecilia Mesa-Arango;Agustina Forastiero;Leticia Bernal-Martínez;Manuel Cuenca-Estrella

  • Candida tropicalis Antifungal Cross-Resistance Is Related to Different Azole Target (Erg11p) Modifications

    A. Forastiero;Ac C. Mesa-Arango;Ac C. Mesa-Arango;A. Alastruey-Izquierdo;L. Alcazar-Fuoli

  • Molecular Identification and Antifungal Susceptibility of Yeast Isolates Causing Fungemia Collected in a Population-Based Study in Spain in 2010 and 2011

    Jesús Guinea;Óscar Zaragoza;Pilar Escribano;Estrella Martín-Mazuelos

  • Immune Response of Galleria mellonella against Human Fungal Pathogens

    Nuria Trevijano-Contador;Oscar Zaragoza

  • Cryptococcus neoformans Capsular Enlargement and Cellular Gigantism during Galleria mellonella Infection

    Rocío García-Rodas;Arturo Casadevall;Juan Luís Rodríguez-Tudela;Manuel Cuenca-Estrella

  • Amphotericin B mediates killing in Cryptococcus neoformans through the induction of a strong oxidative burst.

    Fernanda Sangalli-Leite;Liliana Scorzoni;Liliana Scorzoni;Ana Cecilia Mesa-Arango;Ana Cecilia Mesa-Arango;Celia Casas

Frequent Co-Authors

Manuel Cuenca-Estrella
Manuel Cuenca-Estrella Instituto de Salud Carlos III
Arturo Casadevall
Arturo Casadevall Johns Hopkins University
Jesús Guinea
Jesús Guinea Hospital General Universitario Gregorio Marañón
Juan L. Rodriguez-Tudela
Juan L. Rodriguez-Tudela Global Action for Fungal Infections (GAFFI)
Maria José Soares Mendes-Giannini
Maria José Soares Mendes-Giannini Sao Paulo State University
Javier Pemán
Javier Pemán Hospital Universitari i Politècnic La Fe
Patricia Muñoz
Patricia Muñoz Hospital General Universitario Gregorio Marañón
Jesús Pla
Jesús Pla Complutense University of Madrid
Joshua D. Nosanchuk
Joshua D. Nosanchuk Albert Einstein College of Medicine
Emilia Mellado
Emilia Mellado Instituto de Salud Carlos III

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