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Microbiology

D-Index
79
Citations
19381
World Ranking
1233
National Ranking
79

Overview

Wolfgang Hammerschmidt is affiliated with Ludwig-Maximilians-Universität München in Germany. Their research spans multiple fields, primarily focusing on Medicine and Biochemistry, Genetics and Molecular Biology.

The scientist's subfields of study include Oncology, Epidemiology, Molecular Biology, Infectious Diseases, and Immunology.

Wolfgang Hammerschmidt's main research topics cover a variety of areas related to viral infections and immune response mechanisms:

  • Viral-associated cancers and disorders
  • Cytomegalovirus and herpesvirus research
  • Extracellular vesicles in disease
  • Herpesvirus Infections and Treatments
  • Immune Cell Function and Interaction
  • Lymphoma Diagnosis and Treatment
  • SARS-CoV-2 and COVID-19 Research

The scientist has published regularly in venues such as bioRxiv (Cold Spring Harbor Laboratory), Nucleic Acids Research, Proceedings of the National Academy of Sciences, EMBO Reports, and Journal of Virology.

Notable recent papers by Wolfgang Hammerschmidt include:

  • MicroRNAs are minor constituents of extracellular vesicles that are rarely delivered to target cells (2021), PLoS Genetics
  • Epigenetic lifestyle of Epstein-Barr virus (2020), Seminars in Immunopathology
  • CAR-T Cells Targeting Epstein-Barr Virus gp350 Validated in a Humanized Mouse Model of EBV Infection and Lymphoproliferative Disease (2020), Molecular Therapy - Oncolytics
  • Multiple Viral microRNAs Regulate Interferon Release and Signaling Early during Infection with Epstein-Barr Virus (2021), mBio
  • CD27 is required for protective lytic EBV antigen-specific CD8+ T-cell expansion (2021), Blood

Frequent collaborators in their research include Reinhard Zeidler, Dagmar Pich, Manuel Albanese, Yen-Fu Adam Chen, and Oliver T. Keppler. The collaboration reflects a consistent network across multiple projects.

Best Publications

  • Propagation and recovery of intact, infectious Epstein–Barr virus from prokaryotic to human cells

    Henri Jacques Delecluse;Tanja Hilsendegen;Dagmar Pich;Reinhard Zeidler

  • Genetic analysis of immortalizing functions of Epstein-Barr virus in human B lymphocytes.

    Wolfgang Hammerschmidt;Bill Sugden

  • Epstein-Barr virus-mediated B-cell proliferation is dependent upon latent membrane protein 1, which simulates an activated CD40 receptor.

    Ellen Kilger;Arnd Kieser;Matthias Baumann;Wolfgang Hammerschmidt

  • Latent membrane protein 1 of Epstein–Barr virus mimics a constitutively active receptor molecule

    Olivier Gires;Ursula Zimber-Strobl;Roberta Gonnella;Marius Ueffing

  • Cloning and mutagenesis of a herpesvirus genome as an infectious bacterial artificial chromosome

    Martin Messerle;Irena Crnkovic;Wolfgang Hammerschmidt;Heike Ziegler

  • The Epstein–Barr virus lytic program is controlled by the co‐operative functions of two transactivators

    Regina Feederle;Manuela Kost;Matthias Baumann;Annette Janz

  • Identification and characterization of oriLyt, a lytic origin of DNA replication of Epstein-Barr virus

    Wolfgang Hammerschmidt;Bill Sugden

  • Cutting Edge: miR-223 and EBV miR-BART15 Regulate the NLRP3 Inflammasome and IL-1β Production

    Moritz Haneklaus;Motti Gerlic;Mariola Kurowska-Stolarska;Ashleigh-Ann Rainey

  • LATENT MEMBRANE PROTEIN 1 OF EPSTEIN-BARR VIRUS INTERACTS WITH JAK3 AND ACTIVATES STAT PROTEINS

    Olivier Gires;Franz Kohlhuber;Ellen Kilger;Matthias Baumann

  • Epstein–Barr virus latent membrane protein-1 triggers AP-1 activity via the c-Jun N-terminal kinase cascade

    Arnd Kieser;Ellen Kilger;Olivier Gires;Marius Ueffing

  • B-cell proliferation and induction of early G1-regulating proteins by Epstein-Barr virus mutants conditional for EBNA2.

    Bettina Kempkes;Dimitry Spitkovsky;Pidder Jansen-Dürr;Joachim W. Ellwart

  • Epstein-Barr virus provides a new paradigm: a requirement for the immediate inhibition of apoptosis.

    Markus Altmann;Wolfgang Hammerschmidt

  • Epstein-Barr virus latent membrane protein 2A is a B-cell receptor mimic and essential for B-cell survival

    Christoph Mancao;Wolfgang Hammerschmidt

  • Micro RNAs of Epstein-Barr Virus Promote Cell Cycle Progression and Prevent Apoptosis of Primary Human B Cells

    Eri Seto;Andreas Moosmann;Sebastian Grömminger;Nicole Walz

  • Effective and long-term control of EBV PTLD after transfer of peptide-selected T cells

    Andreas Moosmann;Iris Bigalke;Johanna Tischer;Leah Schirrmann

  • The EBV nuclear antigen 1 (EBNA1) enhances B cell immortalization several thousandfold.

    Sibille Humme;Gilbert Reisbach;Regina Feederle;Henri Jacques Delecluse

  • Human origin recognition complex binds to the region of the latent origin of DNA replication of Epstein–Barr virus

    Aloys Schepers;Marion Ritzi;Kristine Bousset;Elisabeth Kremmer

  • Downregulation of TAP1 in B lymphocytes by cellular and Epstein-Barr virus-encoded interleukin-10

    Reinhard Zeidler;Günther Eissner;Petra Meissner;Stephan Uebel

  • Rescue of "crippled" germinal center B cells from apoptosis by Epstein-Barr virus.

    Christoph Mancao;Markus Altmann;Berit Jungnickel;Wolfgang Hammerschmidt

  • AP-1 homolog BZLF1 of Epstein―Barr virus has two essential functions dependent on the epigenetic state of the viral genome

    Markus Kalla;Anne Schmeinck;Martin Bergbauer;Dagmar Pich

Frequent Co-Authors

Henri Jacques Delecluse
Henri Jacques Delecluse Grenoble Alpes University
Bill Sugden
Bill Sugden University of Wisconsin–Madison
Georg W. Bornkamm
Georg W. Bornkamm Technical University of Munich
Hanns Ludwig
Hanns Ludwig Freie Universität Berlin
Helmut Blum
Helmut Blum Ludwig-Maximilians-Universität München
Christian Münz
Christian Münz University of Zurich
Adam Grundhoff
Adam Grundhoff Heinrich-Pette-Institute
Benjamin Audit
Benjamin Audit École Normale Supérieure de Lyon
marius ueffing
marius ueffing University of Tübingen
Gunnar Schotta
Gunnar Schotta Ludwig-Maximilians-Universität München

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