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Molecular Biology

D-Index
92
Citations
27011
World Ranking
703
National Ranking
59

Overview

Georg W. Bornkamm is affiliated with the Technical University of Munich in Germany. Their research spans multiple disciplines within the life sciences, with a particular focus on biochemistry, genetics, molecular biology, and medicine. Bornkamm's work addresses critical areas such as cancer research, molecular biology, oncology, and pulmonary and respiratory medicine.

The scientist's recent publication record includes the following papers:

  • 7-Dehydrocholesterol is an endogenous suppressor of ferroptosis, 2024, Nature
  • ERK phosphorylation is RAF independent in naïve and activated B cells but RAF dependent in plasma cell differentiation, 2021, Science Signaling
  • Burkitt's Lymphoma and Early B Cell Transformation as Paradigms of How Epstein-Barr Virus Overcomes Apoptosis and Ferroptosis, 2025, Current topics in microbiology and immunology

Bornkamm has collaborated with several researchers, frequently working alongside:

  • Florêncio Porto Freitas
  • Hamed Alborzinia
  • Ancély Ferreira dos Santos
  • Palina Nepachalovich
  • Lohans Pedrera

The research topics covered by Bornkamm include:

  • Cancer, Lipids, and Metabolism
  • Ferroptosis and cancer prognosis
  • RNA modifications and cancer
  • Melanoma and MAPK Pathways
  • PI3K/AKT/mTOR signaling in cancer
  • Cytokine Signaling Pathways and Interactions

Frequent publication venues for their work are:

  • Nature
  • Science Signaling
  • Current topics in microbiology and immunology

The scientist's research contributes to understanding complex molecular mechanisms underlying cancer development, immune cell differentiation, and cell death pathways such as apoptosis and ferroptosis. Their studies include investigating signaling pathways important for cancer progression, such as MAPK and PI3K/AKT/mTOR, as well as the role of RNA modifications in cancer biology.

Georg W. Bornkamm's work interacts with molecular biology at multiple levels, integrating biochemical processes with clinical aspects in oncology and immunology. This multidisciplinary approach aligns with their involvement in both foundational and applied biomedical research.

Best Publications

  • Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

    Jose Pedro Friedmann Angeli;Manuela Schneider;Bettina Proneth;Yulia Y. Tyurina

  • Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death

    Alexander Seiler;Manuela Schneider;Heidi Förster;Stephan Roth

  • Characterization of EBV‐genome negative “null” and “T” cell lines derived from children with acute lymphoblastic leukemia and leukemic transformed non‐Hodgkin lymphoma

    Ulrich Schneider;Hans-Ulrich Schwenk;Georg Bornkamm

  • T cell lipid peroxidation induces ferroptosis and prevents immunity to infection

    Mai Matsushita;Stefan Bernd Freigang;Christoph Schneider;Marcus Conrad

  • Essential role for mitochondrial thioredoxin reductase in hematopoiesis, heart development, and heart function.

    Marcus Conrad;Cemile Jakupoglu;Stéphanie G. Moreno;Stefanie Lippl

  • Covalently closed circular duplex DNA of Epstein-Barr virus in a human lymphoid cell line.

    Tomas Lindahl;Alice Adams;Gunnar Bjursell;Georg W. Bornkamm

  • Cytoplasmic Thioredoxin Reductase Is Essential for Embryogenesis but Dispensable for Cardiac Development

    Cemile Jakupoglu;Gerhard K. H. Przemeck;Manuela Schneider;Stéphanie G. Moreno

  • Control of cell growth by c-Myc in the absence of cell division

    Marino Schuhmacher;Martin S. Staege;Alexander Pajic;Axel Polack

  • The transcriptional program of a human B cell line in response to Myc

    Marino Schuhmacher;Franz Kohlhuber;Michael Hölzel;Carmen Kaiser

  • The Proto-Oncogene c-myc Is a Direct Target Gene of Epstein-Barr Virus Nuclear Antigen 2

    Carmen Kaiser;Gerhard Laux;Dirk Eick;Nicola Jochner

  • Major histocompatibility complex class II-restricted presentation of a cytosolic antigen by autophagy.

    Falk Nimmerjahn;Slavoljub Milosevic;Uta Behrends;Elizabeth M. Jaffee

  • B-cell proliferation and induction of early G1-regulating proteins by Epstein-Barr virus mutants conditional for EBNA2.

    Bettina Kempkes;Dimitry Spitkovsky;Pidder Jansen-Dürr;Joachim W. Ellwart

  • Identification of a specific sperm nuclei selenoenzyme necessary for protamine thiol cross-linking during sperm maturation

    Henning Pfeifer;Marcus Conrad;Doris Roethlein;Antonios Kyriakopoulos

  • Geographical prevalence of two types of Epstein-Barr virus.

    Ursula Zimber;Hans K. Adldinger;Gilbert M. Lenoir;Michèle Vuillaume

  • Attempts to detect virus-specific DNA in human tumors. I. Nucleic acid hybridizations with complementary RNA of human wart virus

    Harald Zur Hausen;Wolf Meinhof;Wiltrud Scheiber;Georg W. Bornkamm

  • The cystine/cysteine cycle: a redox cycle regulating susceptibility versus resistance to cell death.

    A Banjac;T Perisic;H Sato;H Sato;A Seiler

  • Tumor initiators and promoters in the induction of Epstein-Barr virus.

    Harald zur Hausen;Georg W. Bornkamm;Rainer Schmidt;Erich Hecker

  • The Nuclear Form of Phospholipid Hydroperoxide Glutathione Peroxidase Is a Protein Thiol Peroxidase Contributing to Sperm Chromatin Stability

    M. Conrad;S. G. Moreno;F. Sinowatz;F. Ursini

  • Epstein-Barr virus nuclear antigen 2 exerts its transactivating function through interaction with recombination signal binding protein RBP-J kappa, the homologue of Drosophila Suppressor of Hairless.

    U Zimber-Strobl;L J Strobl;C Meitinger;R Hinrichs

  • New type B isolates of Epstein-Barr virus from Burkitt's lymphoma and from normal individuals in endemic areas.

    L. S. Young;Q. Y. Yao;C. M. Rooney;T. B. Sculley

Frequent Co-Authors

Marcus Conrad
Marcus Conrad Helmholtz Zentrum München
Dirk Eick
Dirk Eick Center for Integrated Protein Science Munich
Gilbert M. Lenoir
Gilbert M. Lenoir International Agency For Research On Cancer
Jean Feuillard
Jean Feuillard University of Limoges
Wolfgang Hammerschmidt
Wolfgang Hammerschmidt Ludwig-Maximilians-Universität München
Elisabeth Kremmer
Elisabeth Kremmer Max Planck Society
Ernst Holler
Ernst Holler University of Regensburg
Bernhard Fleckenstein
Bernhard Fleckenstein University of Erlangen-Nuremberg
Henri Jacques Delecluse
Henri Jacques Delecluse Grenoble Alpes University
Michael Pawlita
Michael Pawlita German Cancer Research Center

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