World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
77
Citations
20437
World Ranking
1355
National Ranking
94

Overview

Bernhard Fleckenstein was affiliated with the University of Erlangen-Nuremberg in Germany. Their research spanned multiple interconnected fields, focusing primarily on immunology and microbiology as well as medicine and agricultural and biological sciences. Several subfields featured in their work included immunology, epidemiology, agronomy and crop science, ecology, evolution, behavior and systematics, and genetics.

Their research topics were diverse but showed a concentration on immunodeficiency and autoimmune disorders, T-cell and retrovirus studies, animal disease management and epidemiology, vector-borne animal diseases, blood disorders and treatments, interferon and immune responses, and Mycobacterium research and diagnosis.

Among their recent publications were the following papers:

  • Inherited human IFN-γ deficiency underlies mycobacterial disease, 2020, Journal of Clinical Investigation
  • Impaired IL-23-dependent induction of IFN-γ underlies mycobacterial disease in patients with inherited TYK2 deficiency, 2022, The Journal of Experimental Medicine
  • High Th2 cytokine levels and upper airway inflammation in human inherited T-bet deficiency, 2021, The Journal of Experimental Medicine
  • Early Mortality of Brain Cancer Patients and its Connection to Cytomegalovirus Reactivation During Radiochemotherapy, 2020, Clinical Cancer Research
  • A novel positive feedback-loop between the HTLV-1 oncoprotein Tax and NF-κB activity in T-cells, 2020, Retrovirology

Frequent co-authors included:

  • Rui Yang
  • Laurent Abel
  • Jean-Laurent Casanova
  • Jacinta Bustamante
  • Andrea K. Thoma-Kress

The scientist's work was published in several venues more than once, such as:

  • The Journal of Experimental Medicine (2 publications)
  • Journal of Clinical Investigation
  • Clinical Cancer Research
  • Retrovirology
  • International Journal of Molecular Sciences

Their research contributions covered significant areas related to immune system disorders, retroviral infections, and disease epidemiology, reflecting a multidisciplinary approach that integrated immunology with broader biological and medical sciences.

Best Publications

  • A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus

    Michael Boshart;Frank Weber;Gerhard Jahn;Karoline Dorsch-Häsler

  • The family Herpesviridae: an update. The Herpesvirus Study Group of the International Committee on Taxonomy of Viruses.

    B. Roizmann;R. C. Desrosiers;B. Fleckenstein;C. Lopez

  • Primary structure of the herpesvirus saimiri genome.

    J C Albrecht;J Nicholas;D Biller;K R Cameron

  • Cell-homologous genes in the Kaposi's sarcoma-associated rhadinovirus human herpesvirus 8: determinants of its pathogenicity?

    Frank Neipel;Jens-Christian Albrecht;Bernhard Fleckenstein

  • Transformation to continuous growth of primary human T lymphocytes by human T-cell leukemia virus type I X-region genes transduced by a herpesvirus saimiri vector

    Ralph Grassmann;Christine Dengler;Ingrid Muller-Fleckenstein;Bernhard Fleckenstein

  • Role of human T-cell leukemia virus type 1 X region proteins in immortalization of primary human lymphocytes in culture.

    R Grassmann;S Berchtold;I Radant;M Alt

  • Revisiting Human IL-12Rβ1 Deficiency: A Survey of 141 Patients From 30 Countries

    Ludovic de Beaucoudrey;Arina Samarina;Arina Samarina;Arina Samarina;Jacinta Bustamante;Jacinta Bustamante;Aurélie Cobat;Aurélie Cobat

  • Stable growth transformation of human T lymphocytes by herpesvirus saimiri.

    Brigitte Biesinger;Ingrid Muller-Fleckenstein;Birgit Simmer;Gerlinde Lang

  • Human herpesvirus 8 encodes a homolog of interleukin-6.

    F. Neipel;J.-C. Albrecht;A. Ensser;Y.-Q. Huang

  • Kaposi's sarcoma-associated herpesvirus encodes a functional cyclin.

    M Li;H Lee;D W Yoon;J C Albrecht

  • Deregulation of cell growth by the K1 gene of Kaposi's sarcoma-associated herpesvirus.

    Heuiran Lee;Ronald Veazey;Kenneth Williams;Mengtao Li

  • Herpes viral cyclin/Cdk6 complexes evade inhibition by CDK inhibitor proteins.

    Charles Swanton;David J. Mann;Bernhard Fleckenstein;Frank Neipel

  • Human TYK2 deficiency: Mycobacterial and viral infections without hyper-IgE syndrome

    Alexandra Y. Kreins;Alexandra Y. Kreins;Michael J. Ciancanelli;Satoshi Okada;Xiao Fei Kong

  • Herpesvirus saimiri and Herpesvirus ateles

    Bernhard Fleckenstein;Ronald C. Desrosiers

  • Cloning of the complete human cytomegalovirus genome in cosmids.

    Bernhard Fleckenstein;Ingrid Müller;John Collins

  • Cell surface heparan sulfate is a receptor for human herpesvirus 8 and interacts with envelope glycoprotein K8.1.

    Alexander Birkmann;Kerstin Mahr;Armin Ensser;Svenja Yağuboğlu

  • Human herpesvirus type 8 interleukin-6 homologue is functionally active on human myeloma cells.

    Renate Burger;Frank Neipel;Bernhard Fleckenstein;Rocco Savino

  • Primary structure and transcription of the genes coding for the two virion phosphoproteins pp65 and pp71 of human cytomegalovirus.

    B Rüger;S Klages;B Walla;J Albrecht

  • Human herpesvirus-6 strain groups: a nomenclature

    D. Ablashi;H. Agut;Z. Berneman;G. Campadelli-Fiume

  • Kaposi’s Sarcoma-Associated Herpesvirus Viral Interferon Regulatory Factor

    Mengtao Li;Heuiran Lee;Jie Guo;Frank Neipel

Frequent Co-Authors

Gerhard Jahn
Gerhard Jahn University of Tübingen
Joachim R. Kalden
Joachim R. Kalden University of Erlangen-Nuremberg
Helmut Fickenscher
Helmut Fickenscher Kiel University
Laurent Abel
Laurent Abel Université Paris Cité
Stéphanie Boisson-Dupuis
Stéphanie Boisson-Dupuis Université Paris Cité
Jacinta Bustamante
Jacinta Bustamante Rockefeller University
Ronald C. Desrosiers
Ronald C. Desrosiers University of Miami
Stuart G. Tangye
Stuart G. Tangye Garvan Institute of Medical Research
Jean-Laurent Casanova
Jean-Laurent Casanova The University of Texas Southwestern Medical Center

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