World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
88
Citations
29652
World Ranking
1163
National Ranking
615

Medicine

D-Index
89
Citations
29800
World Ranking
12670
National Ranking
6480

Overview

Jacinta Bustamante is affiliated with Rockefeller University in the United States and has made extensive contributions to the fields of immunology, microbiology, medicine, and molecular biology. Their research primarily focuses on immunodeficiency and autoimmune disorders, immune cell function and interaction, and specific infectious diseases such as tuberculosis and mycobacterial infections. Additional focal areas include blood disorders and the immunological mechanisms involving T-cells, B-cells, neutrophils, and oxidative processes.

Recent notable papers by Bustamante include "X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19" published in 2021 in Science Immunology, "Human genetic and immunological determinants of critical COVID-19 pneumonia" published in 2022 in Nature, and "A Global Effort to Define the Human Genetics of Protective Immunity to SARS-CoV-2 Infection" published in 2020 in Cell. Earlier work includes "Mendelian susceptibility to mycobacterial disease: recent discoveries" published in 2020 in Human Genetics and "Inborn errors of OAS-RNase L in SARS-CoV-2-related multisystem inflammatory syndrome in children" published in 2022 in Science.

Bustamante frequently collaborates with a core group of coauthors, including Jean-Laurent Casanova, Stéphanie Boisson-Dupuis, Laurent Abel, Jérémie Rosain, and Anne Puel. These collaborations reflect a sustained research network focused on the genetic and immunological bases of infectious and autoimmune diseases.

The scientist's research has been disseminated through several key scientific journals. Most publications appear in the Journal of Clinical Immunology, followed by The Journal of Experimental Medicine, Cell, Journal of Human Immunity, and Science Immunology. These venues indicate a strong presence in top-tier immunology and medical journals.

Bustamante's work spans multiple interconnected disciplines with a majority of publications in immunology and microbiology, followed by medicine and biochemistry, genetics, and molecular biology. Their specialized subfields include immunology, genetics, epidemiology, infectious diseases, and molecular biology, illustrating a multidisciplinary approach to studying immune function and genetic susceptibility to disease.

  • Immunodeficiency and Autoimmune Disorders
  • Immune Cell Function and Interaction
  • Mycobacterium research and diagnosis
  • Tuberculosis Research and Epidemiology
  • Blood disorders and treatments
  • T-cell and B-cell Immunology
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms

  • Jean-Laurent Casanova
  • Stéphanie Boisson-Dupuis
  • Laurent Abel
  • Jérémie Rosain
  • Anne Puel

  • Journal of Clinical Immunology
  • The Journal of Experimental Medicine
  • Cell
  • Journal of Human Immunity
  • Science Immunology

  • Immunology and Microbiology
  • Medicine
  • Biochemistry, Genetics and Molecular Biology

  • Immunology
  • Genetics
  • Epidemiology
  • Infectious Diseases
  • Molecular Biology

Best Publications

  • Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

    Qian Zhang;Paul Bastard;Paul Bastard;Zhiyong Liu;Jérémie Le Pen

  • Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity

    Anne Puel;Sophie Cypowyj;Jacinta Bustamante;Jill Wright

  • Chronic Mucocutaneous Candidiasis in Humans with Inborn Errors of Interleukin-17 Immunity

    Anne Puel;Sophie Cypowyj;Jacinta Bustamante;Jill F. Wright

  • Gain-of-function human STAT1 mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis

    Luyan Liu;Satoshi Okada;Xiao Fei Kong;Alexandra Y. Kreins

  • Pyogenic Bacterial Infections in Humans with IRAK-4 Deficiency

    Unknown

  • Mendelian susceptibility to mycobacterial disease: genetic, immunological, and clinical features of inborn errors of IFN-γ immunity

    Jacinta Bustamante;Jacinta Bustamante;Jacinta Bustamante;Stéphanie Boisson-Dupuis;Laurent Abel;Jean-Laurent Casanova

  • Autoantibodies against IL-17A, IL-17F, and IL-22 in patients with chronic mucocutaneous candidiasis and autoimmune polyendocrine syndrome type I

    Anne Puel;Anne Puel;Rainer Döffinger;Angels Natividad;Angels Natividad;Maya Chrabieh;Maya Chrabieh

  • IRF8 mutations and human dendritic-cell immunodeficiency.

    Sophie Hambleton;Sandra Salem;Jacinta Bustamante;Venetia Bigley

  • Autoantibodies neutralizing type I IFNs are present in ~ 4% of uninfected individuals over 70 years old and account for ~ 20% of COVID-19 deaths.

    Paul Bastard;Adrian Gervais;Adrian Gervais;Tom Le Voyer;Tom Le Voyer;Jérémie Rosain;Jérémie Rosain

  • Mycobacterial Disease and Impaired IFN-γ Immunity in Humans with Inherited ISG15 Deficiency

    Dusan Bogunovic;Minji Byun;Larissa A. Durfee;Avinash Abhyankar

  • Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation

    Xianqin Zhang;Dusan Bogunovic;Béatrice Payelle-Brogard;Véronique Francois-Newton

  • The European Society for Immunodeficiencies (ESID) Registry Working Definitions for the Clinical Diagnosis of Inborn Errors of Immunity

    Markus G. Seidel;Gerhard Kindle;Benjamin Gathmann;Isabella Quinti

  • Human genetic and immunological determinants of critical COVID-19 pneumonia

    Unknown

  • Inborn errors of IL-12/23- and IFN-gamma-mediated immunity: molecular, cellular, and clinical features.

    Orchidée Filipe-Santos;Jacinta Bustamante;Ariane Chapgier;Guillaume Vogt

  • Systemic Human ILC Precursors Provide a Substrate for Tissue ILC Differentiation.

    Ai Ing Lim;Ai Ing Lim;Ai Ing Lim;Yan Li;Yan Li;Silvia Lopez-Lastra;Silvia Lopez-Lastra;Silvia Lopez-Lastra;Ralph Stadhouders

  • B cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans

    Danielle T. Avery;Elissa K. Deenick;Elissa K. Deenick;Cindy S. Ma;Cindy S. Ma;Santi Suryani;Santi Suryani

  • Revisiting Human IL-12Rβ1 Deficiency: A Survey of 141 Patients From 30 Countries

    Ludovic de Beaucoudrey;Arina Samarina;Arina Samarina;Arina Samarina;Jacinta Bustamante;Jacinta Bustamante;Aurélie Cobat;Aurélie Cobat

  • Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations

    Satoshi Okada;Satoshi Okada;Janet G Markle;Elissa K Deenick;Elissa K Deenick;Federico Mele

  • Inborn errors of interferon (IFN)-mediated immunity in humans: insights into the respective roles of IFN-alpha/beta, IFN-gamma, and IFN-lambda in host defense.

    Shen-Ying Zhang;Stéphanie Boisson-Dupuis;Stéphanie Boisson-Dupuis;Ariane Chapgier;Ariane Chapgier;Kun Yang;Kun Yang

  • X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19.

    Takaki Asano;Bertrand Boisson;Bertrand Boisson;Bertrand Boisson;Fanny Onodi;Daniela Matuozzo;Daniela Matuozzo

  • Human TRAF3 Adaptor Molecule Deficiency Leads to Impaired Toll-like Receptor 3 Response and Susceptibility to Herpes Simplex Encephalitis

    Rebeca Pérez de Diego;Rebeca Pérez de Diego;Rebeca Pérez de Diego;Vanessa Sancho-Shimizu;Vanessa Sancho-Shimizu;Vanessa Sancho-Shimizu;Lazaro Lorenzo;Lazaro Lorenzo;Lazaro Lorenzo;Anne Puel;Anne Puel;Anne Puel

  • Low Penetrance, Broad Resistance, and Favorable Outcome of Interleukin 12 Receptor β1 Deficiency Medical and Immunological Implications

    Claire Fieschi;Stéphanie Dupuis;Emilie Catherinot;Jacqueline Feinberg

  • Functional STAT3 deficiency compromises the generation of human T follicular helper cells

    Cindy S. Ma;Cindy S. Ma;Danielle T. Avery;Anna Chan;Marcel Batten;Marcel Batten

Frequent Co-Authors

Jean-Laurent Casanova
Jean-Laurent Casanova The University of Texas Southwestern Medical Center
Stéphanie Boisson-Dupuis
Stéphanie Boisson-Dupuis Université Paris Cité
Laurent Abel
Laurent Abel Université Paris Cité
Capucine Picard
Capucine Picard Université Paris Cité
Stuart G. Tangye
Stuart G. Tangye Garvan Institute of Medical Research
Bertrand Boisson
Bertrand Boisson Rockefeller University
Cindy S. Ma
Cindy S. Ma Garvan Institute of Medical Research
Emmanuelle Jouanguy
Emmanuelle Jouanguy Necker-Enfants Malades Hospital
Elissa K. Deenick
Elissa K. Deenick Garvan Institute of Medical Research

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