Alexandra F. Freeman mainly focuses on Immunology, Dock8, Immunodeficiency, Job Syndrome and Immunopathology. The study incorporates disciplines such as Mutation, Monocytopenia and Pathology in addition to Immunology. Her study in Dock8 is interdisciplinary in nature, drawing from both Signal transduction, Interleukin 17 and Lymphocyte.
Her Immunodeficiency study integrates concerns from other disciplines, such as Hematopoietic stem cell transplantation, Respiratory tract infections, Cdc42 GTP-Binding Protein, Chemotaxis and Internal medicine. She works mostly in the field of Job Syndrome, limiting it down to topics relating to Connective tissue and, in certain cases, Etiology, Proinflammatory cytokine, Molecular biology, STAT3 GOF and STAT3, as a part of the same area of interest. Her Immunopathology research includes themes of Periodontitis, Cellular differentiation, Homeostasis, Immune tolerance and Rash.
Alexandra F. Freeman mostly deals with Immunology, Internal medicine, Immunoglobulin E, Primary immunodeficiency and Immunodeficiency. Her Immunology study frequently links to related topics such as Disease. Her Internal medicine research includes elements of Gastroenterology, Endocrinology and Cardiology.
Her Immunoglobulin E course of study focuses on STAT3 and Cancer research. Alexandra F. Freeman interconnects Chronic mucocutaneous candidiasis and Connective tissue in the investigation of issues within Primary immunodeficiency. Her Dock8 research is multidisciplinary, relying on both Malignancy and Lymphocyte.
Alexandra F. Freeman mainly investigates Immunology, STAT3, Immune system, Primary immunodeficiency and Immunoglobulin E. Her Immunology research incorporates themes from Hematopoietic stem cell transplantation and Disease. The various areas that Alexandra F. Freeman examines in her STAT3 study include Cancer research and STAT1.
The Immune system study combines topics in areas such as Cell and Signal transduction. As part of the same scientific family, Alexandra F. Freeman usually focuses on Primary immunodeficiency, concentrating on Transplantation and intersecting with Gastroenterology and Immunity. Her work deals with themes such as Medical microbiology and Genetic testing, which intersect with Immunoglobulin E.
Her primary scientific interests are in Immunology, Immune system, Immunodeficiency, STAT3 and Immune dysregulation. Her studies in Immunology integrate themes in fields like Loss function, Disease and Staphylococcus aureus. Her research integrates issues of Secretion, Cell signaling, Signal transduction and Inflammatory bowel disease in her study of Immune system.
Her studies deal with areas such as Hematopoietic stem cell transplantation and Internal medicine, Retrospective cohort study as well as Immunodeficiency. She has researched STAT3 in several fields, including Immunoglobulin E and STAT1. As a part of the same scientific study, Alexandra F. Freeman usually deals with the Immune dysregulation, concentrating on Primary immunodeficiency and frequently concerns with Penetrance, Haploinsufficiency, Hypogammaglobulinemia and Common variable immunodeficiency.
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Impaired T H 17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome
Joshua D. Milner;Jason M. Brenchley;Jason M. Brenchley;Arian Laurence;Alexandra F. Freeman.
STAT3 Mutations in the Hyper-IgE Syndrome
Steven M. Holland;Frank R. DeLeo;Houda Z. Elloumi;Amy P. Hsu.
The New England Journal of Medicine (2007)
Combined Immunodeficiency Associated with DOCK8 Mutations
Qian Zhang;Jeremiah C. Davis;Ian T. Lamborn;Alexandra F. Freeman.
The New England Journal of Medicine (2009)
GATA2 deficiency: a protean disorder of hematopoiesis, lymphatics and immunity
Michael A. Spinner;Lauren A. Sanchez;Amy P. Hsu;Pamela A. Shaw.
Mutations in GATA2 are associated with the autosomal dominant and sporadic monocytopenia and mycobacterial infection (MonoMAC) syndrome
Amy P. Hsu;Elizabeth P. Sampaio;Javed Khan;Katherine R. Calvo.
Expansion of the Human Phenotype Ontology (HPO) knowledge base and resources
Sebastian Köhler;Leigh Carmody;Nicole A. Vasilevsky;Julius O. B. Jacobsen.
Nucleic Acids Research (2019)
Cold urticaria, immunodeficiency, and autoimmunity related to PLCG2 deletions.
Michael J. Ombrello;Elaine F. Remmers;Guangping Sun;Alexandra F. Freeman.
The New England Journal of Medicine (2012)
Autosomal dominant and sporadic monocytopenia with susceptibility to mycobacteria, fungi, papillomaviruses, and myelodysplasia
Donald C. Vinh;Smita Y. Patel;Gulbu Uzel;Victoria L. Anderson.
Common Severe Infections in Chronic Granulomatous Disease
Beatriz E. Marciano;Christine Spalding;Alan Fitzgerald;Daphne Mann.
Clinical Infectious Diseases (2015)
Mutations in STAT3 and diagnostic guidelines for hyper-IgE syndrome
Cristina Woellner;E. Michael Gertz;Alejandro A. Schäffer;Macarena Lagos.
The Journal of Allergy and Clinical Immunology (2010)
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