What is he best known for?
The fields of study he is best known for:
- Enzyme
- Organic chemistry
- Biochemistry
Jiri Gut spends much of his time researching Plasmodium falciparum, Stereochemistry, Biochemistry, Cysteine protease and Proteases.
Particularly relevant to Antimalarial Agent is his body of work in Plasmodium falciparum.
His Stereochemistry research is multidisciplinary, relying on both In vitro, Structure–activity relationship and Chemical synthesis.
His studies link Trypanosoma cruzi with Biochemistry.
His biological study deals with issues like Globin, which deal with fields such as Plasmodium berghei.
Jiri Gut combines subjects such as Kinetoplastida, Trypanosoma brucei, Protease inhibitor, Cysteine and Enzyme inhibitor with his study of Proteases.
His most cited work include:
- Chemical genetics of Plasmodium falciparum. (442 citations)
- Tetracyclines Specifically Target the Apicoplast of the Malaria Parasite Plasmodium falciparum (207 citations)
- Synthesis and structure-activity relationships of parasiticidal thiosemicarbazone cysteine protease inhibitors against Plasmodium falciparum, Trypanosoma brucei, and Trypanosoma cruzi. (205 citations)
What are the main themes of his work throughout his whole career to date?
His scientific interests lie mostly in Plasmodium falciparum, Stereochemistry, Biochemistry, In vitro and Cysteine protease.
His Plasmodium falciparum study improves the overall literature in Malaria.
His studies in Stereochemistry integrate themes in fields like Combinatorial chemistry, Biological activity, IC50 and Chemical synthesis.
His Proteases, Trypanosoma brucei and Amino acid study in the realm of Biochemistry interacts with subjects such as Antiparasitic.
The concepts of his In vitro study are interwoven with issues in Artemisinin and Primaquine.
His study looks at the relationship between Cysteine protease and fields such as Virtual screening, as well as how they intersect with chemical problems.
He most often published in these fields:
- Plasmodium falciparum (56.80%)
- Stereochemistry (41.42%)
- Biochemistry (28.40%)
What were the highlights of his more recent work (between 2013-2020)?
- Plasmodium falciparum (56.80%)
- Stereochemistry (41.42%)
- Biochemistry (28.40%)
In recent papers he was focusing on the following fields of study:
Jiri Gut focuses on Plasmodium falciparum, Stereochemistry, Biochemistry, Pharmacology and Chloroquine.
His Plasmodium falciparum research is multidisciplinary, incorporating elements of In vitro, Structure–activity relationship, Cytotoxicity, Combinatorial chemistry and Plasmodium berghei.
His In vitro research incorporates elements of Drug metabolism, Cysteine protease and Virtual screening.
He has researched Stereochemistry in several fields, including IC50, Isatin and Hemozoin.
His Biochemistry research integrates issues from Artemisinin, Parasitemia, Chlorine atom and Primaquine.
Jiri Gut interconnects Potency, Malaria, Chagas disease, Trypanosoma cruzi and In vivo in the investigation of issues within Pharmacology.
Between 2013 and 2020, his most popular works were:
- A potent antimalarial benzoxaborole targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue. (58 citations)
- Repurposing auranofin as a lead candidate for treatment of lymphatic filariasis and onchocerciasis. (50 citations)
- 7-chloroquinoline-isatin conjugates: antimalarial, antitubercular, and cytotoxic evaluation. (39 citations)
In his most recent research, the most cited papers focused on:
- Enzyme
- Organic chemistry
- Biochemistry
His primary areas of study are Plasmodium falciparum, Stereochemistry, Structure–activity relationship, Chloroquine and Plasmodium berghei.
As a part of the same scientific study, Jiri Gut usually deals with the Plasmodium falciparum, concentrating on IC50 and frequently concerns with Amino acid.
His Stereochemistry research includes elements of Combinatorial chemistry and Isatin.
He focuses mostly in the field of Chloroquine, narrowing it down to topics relating to Lumefantrine and, in certain cases, Pharmacology.
His Plasmodium berghei study incorporates themes from Peptide sequence, Sequence alignment, Artemisinin and Microbiology.
In his study, which falls under the umbrella issue of Artemisinin, In vivo is strongly linked to Biochemistry.
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