World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
59
Citations
11923
World Ranking
10175
National Ranking
2831

Biology and Biochemistry

D-Index
60
Citations
11879
World Ranking
12044
National Ranking
5162

Overview

Jiri Gut is affiliated with the University of California, San Francisco in the United States. Their research spans multiple interdisciplinary fields, including Medicine, Computer Science, and Chemistry. Within these broader domains, their work focuses on subfields such as Public Health, Environmental and Occupational Health, Computational Theory and Mathematics, and Organic Chemistry.

The core topics of Jiri Gut's research encompass Malaria Research and Control, Computational Drug Discovery Methods, and Synthesis and Catalytic Reactions. The scientist's publications reflect a concentration on medicinal chemistry with a particular emphasis on antimalarial compounds and drug development strategies.

Notable recent papers by Jiri Gut include:

  • "Antimalarial Trioxolanes with Superior Drug-Like Properties and In Vivo Efficacy," published in 2020 in ACS Infectious Diseases
  • "Artefenomel Regioisomer RLA-3107 Is a Promising Lead for the Discovery of Next-Generation Endoperoxide Antimalarials," published in 2023 in ACS Medicinal Chemistry Letters

These publications illustrate contributions to the development and evaluation of novel antimalarial agents, highlighting chemical properties and biological efficacy.

Jiri Gut frequently collaborates with a group of researchers active in related fields. Frequent co-authors include:

  • Brian R. Blank
  • Philip J. Rosenthal
  • Adam R. Renslo
  • Ryan L. Gonciarz
  • Poulami Talukder

Thevenues where their research has been published reflect the integration of chemistry and medical research:

  • ACS Infectious Diseases
  • ACS Medicinal Chemistry Letters

This combination of research interests and publication record positions Jiri Gut as an active contributor to both chemical and computational methodologies aimed at addressing infectious diseases, particularly malaria. Their profile exhibits a focus on applied research involving drug discovery and public health implications.

Best Publications

  • Chemical genetics of Plasmodium falciparum.

    W. Armand Guiguemde;Anang A. Shelat;David Bouck;Sandra Duffy

  • Tetracyclines Specifically Target the Apicoplast of the Malaria Parasite Plasmodium falciparum

    Erica L. Dahl;Jennifer L. Shock;Bhaskar R. Shenai;Jiri Gut

  • Synthesis and structure-activity relationships of parasiticidal thiosemicarbazone cysteine protease inhibitors against Plasmodium falciparum, Trypanosoma brucei, and Trypanosoma cruzi.

    Doron C. Greenbaum;Zachary Mackey;Elizabeth Hansell;Patricia Doyle

  • Expression and characterization of the Plasmodium falciparum haemoglobinase falcipain-3.

    Puran S. Sijwali;Bhaskar R. Shenai;Jiri Gut;Ajay Singh

  • Synthesis and evaluation of new antimalarial phenylurenyl chalcone derivatives.

    José N Domínguez;Caritza León;Juan Rodrigues;Neira Gamboa de Domínguez

  • Design, synthesis and in vitro antimalarial evaluation of triazole-linked chalcone and dienone hybrid compounds

    Eric M. Guantai;Kanyile Ncokazi;Timothy J. Egan;Jiri Gut

  • Synthesis, antimalarial and antitubercular activity of acetylenic chalcones

    Renate H. Hans;Eric M. Guantai;Carmen Lategan;Peter J. Smith

  • Design, synthesis and anti-plasmodial evaluation in vitro of new 4-aminoquinoline isatin derivatives

    Idan Chiyanzu;Cailean Clarkson;Peter J. Smith;Julie Lehman

  • Discovery of potent thiosemicarbazone inhibitors of rhodesain and cruzain.

    Naoaki Fujii;Jeremy P. Mallari;Elizabeth J. Hansell;Z. Mackey

  • A novel multi-domain mucin-like glycoprotein of Cryptosporidium parvum mediates invasion,

    Debra A Barnes;Alain Bonnin;Jin-Xing Huang;Laurent Gousset

  • Synthesis and antimalarial activity of sulfonamide chalcone derivatives

    José N. Domínguez;Caritza León;Juan Rodrigues;Neira Gamboa de Domínguez

  • Composition and anti-plasmodial activities of essential oils from some Cameroonian medicinal plants.

    Fabrice Fekam Boyom;Vincent Ngouana;Paul Henri Amvam Zollo;Chantal Menut

  • Synthesis and evaluation of isatins and thiosemicarbazone derivatives against cruzain, falcipain-2 and rhodesain.

    Idan Chiyanzu;Elizabeth Hansell;Jiri Gut;Philip J. Rosenthal

  • Antimalarial Activity of Human Immunodeficiency Virus Type 1 Protease Inhibitors

    Sunil Parikh;Jiri Gut;Eva Istvan;Daniel E. Goldberg

  • A reprofiled drug, auranofin, is effective against metronidazole-resistant Giardia lamblia

    Noa Tejman-Yarden;Yukiko Miyamoto;David Leitsch;Jennifer Santini

  • Plasmodium falciparum cysteine protease falcipain-1 is not essential in erythrocytic stage malaria parasites

    Puran S. Sijwali;Kentaro Kato;Karl B. Seydel;Jiri Gut

  • Azide-alkyne cycloaddition en route to 1H-1,2,3-triazole-tethered 7-chloroquinoline-isatin chimeras: synthesis and antimalarial evaluation

    Raghu Raj;Pardeep Singh;Parvesh Singh;Jiri Gut

  • WormAssay: a novel computer application for whole-plate motion-based screening of macroscopic parasites.

    Chris Marcellino;Jiri Gut;K. C. Lim;Rahul Singh

  • A potent antimalarial benzoxaborole targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue.

    Ebere Sonoiki;Ebere Sonoiki;Caroline L. Ng;Marcus C.S. Lee;Denghui Guo

  • Identification of Novel Parasitic Cysteine Protease Inhibitors Using Virtual Screening. 1. The ChemBridge Database

    Prashant V. Desai;Akshay Patny;Yogesh Sabnis;Babu Tekwani

  • Antimalarial activity of human immunodefic iency virus type 1 protease inhibitors

    Sunil Parikh;Jiri Gut;Eva Istvan

Frequent Co-Authors

Philip J. Rosenthal
Philip J. Rosenthal University of California, San Francisco
Kelly Chibale
Kelly Chibale University of Cape Town
James H. McKerrow
James H. McKerrow University of California, San Diego
Mitchell A. Avery
Mitchell A. Avery University of Mississippi
Michelle R. Arkin
Michelle R. Arkin University of California, San Francisco
Peter Smith
Peter Smith University of Aberdeen
Paul M. O'Neill
Paul M. O'Neill University of Liverpool
Babu L. Tekwani
Babu L. Tekwani Southern Research Institute
Maria M. Mota
Maria M. Mota University of Lisbon
Joseph L. DeRisi
Joseph L. DeRisi University of California, San Francisco

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For students interested in expanding their career options beyond traditional Chemistry, numerous related fields offer online degree programs that can be completed flexibly and affordably. Understanding how much is criminal justice school is a crucial first step for those considering this alternative pathway, as costs can vary widely depending on the program.

One popular route is pursuing the best online criminal justice associate degree, which provides foundational knowledge and skills applicable to law enforcement, legal support, or federal agencies. Those interested in the legal field might also explore different types of paralegals, offering opportunities to support attorneys without attending law school, and can be a natural complement to scientific expertise in patent or environmental law.

Another career pathway linked to Chemistry is pharmaceutical sales. Exploring the pharmaceutical sales salary and career paths helps students understand the potential earnings and growth opportunities in this industry, combining scientific knowledge with business and communication skills.

Considering these related online degrees and careers can significantly broaden the professional horizons for Chemistry students, providing practical options aligned with diverse interests and goals.

Best Scientists Citing Jiri Gut

Trending Scientists

Recently Published Articles