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Chemistry

D-Index
59
Citations
10927
World Ranking
10286
National Ranking
2850

Overview

Mitchell A. Avery is affiliated with the University of Mississippi in the United States. Their research primarily focuses on the field of Medicine, with particular attention to public health, environmental and occupational health, organic chemistry, computational theory and mathematics, epidemiology, and materials chemistry.

Avery's work encompasses a variety of topics, including malaria research and control, computational drug discovery methods, Trypanosoma species research and implications, chemical synthesis and alkaloids, cholinesterase and neurodegenerative diseases, synthesis and characterization of pyrroles, and phenothiazines and benzothiazines synthesis and activities.

Significant recent publications by Avery include the following papers:

  • Isolation and Synthesis of Veranamine, an Antidepressant Lead from the Marine Sponge Verongula rigida, 2020, Journal of Natural Products
  • Structure-Activity Relationships of the Antimalarial Agent Artemisinin 10. Synthesis and Antimalarial Activity of Enantiomers of rac-5β-Hydroxy-d-Secoartemisinin and Analogs: Implications Regarding the Mechanism of Action, 2021, Molecules
  • Selective Inhibition of Plasmodium falciparum ATPase 6 by Artemisinins and Identification of New Classes of Inhibitors after Expression in Yeast, 2022, Antimicrobial Agents and Chemotherapy
  • Selective inhibition of PfATP6 by artemisinins and identification of new classes of inhibitors after expression in yeast, 2021, bioRxiv (Cold Spring Harbor Laboratory)
  • CCDC 1883525: Experimental Crystal Structure Determination, 2020, The Cambridge Structural Database

The frequent collaborators in Avery's research include Khaled M. Elokely, H. C. Araújo, Xiong Zhang, Abir T. El-Alfy, and Paulo Carvalho.

Avery's work has been published in several well-regarded venues, including:

  • Journal of Natural Products
  • Molecules
  • Antimicrobial Agents and Chemotherapy
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Cambridge Structural Database

Best Publications

  • Identification of Telmisartan as a Unique Angiotensin II Receptor Antagonist With Selective PPARγ–Modulating Activity

    Stephen C. Benson;Harrihar A. Pershadsingh;Christopher I. Ho;Amar Chittiboyina

  • Stereoselective total synthesis of (+)-artemisinin, the antimalarial constituent of Artemisia annua L

    Mitchell A. Avery;Wesley K. M. Chong;Clive Jennings-White

  • Antimalarial Artemisinin Drugs Induce Cytochrome P450 and MDR1 Expression by Activation of Xenosensors Pregnane X Receptor and Constitutive Androstane Receptor

    Oliver Burk;Katja A. Arnold;Andreas K. Nussler;Elke Schaeffeler

  • Physicochemical Characterization of Berberine Chloride: A Perspective in the Development of a Solution Dosage Form for Oral Delivery

    Sunil Kumar Battu;Michael A. Repka;Sindhuri Maddineni;Amar G. Chittiboyina

  • 1,2-dithiolane derivatives

    Harrihar A. Pershadsingh;Mitchell A. Avery

  • Type 2 Diabetes and Oral Antihyperglycemic Drugs

    Cassia S Mizuno;Amar G Chittiboyina;Theodore W Kurtz;Harrihar A Pershadsingh

  • Targeting the methyl erythritol phosphate (MEP) pathway for novel antimalarial, antibacterial and herbicidal drug discovery: inhibition of 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR) enzyme.

    Nidhi Singh;Gweneal Cheve;Mitchell A. Avery;Christopher R. McCurdy

  • The Total synthesis of (+)-artemisinin and (+)-9-desmethyltemesinin

    Mitchell A. Avery;Clive Jennings-White;Wesley K.M. Chong

  • Current progress in the chemistry, medicinal chemistry and drug design of artemisinin based antimalarials.

    Vroman Ja;Alvim-Gaston M;Avery Ma

  • Identification of Novel Parasitic Cysteine Protease Inhibitors Using Virtual Screening. 1. The ChemBridge Database

    Prashant V. Desai;Akshay Patny;Yogesh Sabnis;Babu Tekwani

  • Comparative phytotoxicity of artemisinin and several sesquiterpene analogues

    Franck E Dayan;Antonio Hernández;Stacy N Allen;Rita M Moraes

  • Structure-activity relationships of the antimalarial agent artemisinin. 8. design, synthesis, and CoMFA studies toward the development of artemisinin-based drugs against leishmaniasis and malaria.

    Mitchell A Avery;Kannoth M Muraleedharan;Prashant V Desai;Achintya K Bandyopadhyaya

  • Antigiardial Activity of Isoflavones from Dalbergia frutescens Bark

    I. A. Khan;M. A. Avery;C. L. Burandt;D. K. Goins

  • Structure-activity relationships of the antimalarial agent artemisinin. 1. Synthesis and comparative molecular field analysis of C-9 analogs of artemisinin and 10-deoxoartemisinin

    Mitchell A. Avery;Fenglan Gao;Wesley K. M. Chong;Sanjiv Mehrotra

  • Manadomanzamines A and B: A Novel Alkaloid Ring System with Potent Activity against Mycobacteria and HIV-1

    Jiangnan Peng;Jin-Feng Hu;Abul B. Kazi;Ze Li

  • Second-generation antimalarial endoperoxides

    Steven R Meshnick;Charles W. Jefford;Gary H. Posner;Mitchell A. Avery

  • Structure−Activity Relationships of the Antimalarial Agent Artemisinin. 6. The Development of Predictive In Vitro Potency Models Using CoMFA and HQSAR Methodologies

    Mitchell A Avery;Maria Alvim-Gaston;Carlos R Rodrigues;Eliezer J Barreiro

  • Nigellidine-4-O-sulfite, the first sulfated indazole-type alkaloid from the seeds of Nigella sativa.

    Zulfiqar Ali;Daneel Ferreira;Paulo Carvalho;Mitchell A. Avery

  • Identification of Novel Parasitic Cysteine Protease Inhibitors by Use of Virtual Screening. 2. The Available Chemical Directory

    Prashant V. Desai;Akshay Patny;Jiri Gut;Philip J. Rosenthal

  • Mollamides B and C, Cyclic hexapeptides from the indonesian tunicate Didemnum molle.

    Marwa S. Donia;Bin Wang;Daniel C. Dunbar;Prashant V. Desai

  • Total synthesis of epothilone A.

    Bin Zhu;James S. Panek

Frequent Co-Authors

Babu L. Tekwani
Babu L. Tekwani Southern Research Institute
Mark T. Hamann
Mark T. Hamann Medical University of South Carolina
Philip J. Rosenthal
Philip J. Rosenthal University of California, San Francisco
Ikhlas A. Khan
Ikhlas A. Khan University of Mississippi
Theodore W. Kurtz
Theodore W. Kurtz University of California, San Francisco
Jiri Gut
Jiri Gut University of California, San Francisco
Larry A. Walker
Larry A. Walker University of Mississippi
Murray Goodman
Murray Goodman University of California, San Diego
Robert C. Speth
Robert C. Speth Nova Southeastern University
James Varani
James Varani University of Michigan–Ann Arbor

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