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Chemistry

D-Index
80
Citations
24608
World Ranking
3395
National Ranking
1117

Overview

Gary H. Posner was affiliated with Johns Hopkins University in the United States. Over the course of their career, they contributed to the fields of biochemistry, genetics, molecular biology, and medicine. Their research spanned several subfields including radiology, nuclear medicine and imaging, cell biology, and molecular biology.

Their scientific work focused on topics such as monoclonal and polyclonal antibodies research, skin and cellular biology research, and glycosylation and glycoproteins research. These themes were reflected across multiple publications and investigations during their career.

Among the papers authored or co-authored by Gary H. Posner was the 2020 study titled "Artemisinins target the intermediate filament protein vimentin for human cytomegalovirus inhibition", published in the Journal of Biological Chemistry. This paper received citations from subsequent research, indicating engagement within the scientific community.

Frequent collaborators included Sujayita Roy, Arun Kapoor, Fei Zhu, Rupkatha Mukhopadhyay, and Ayan Kumar Ghosh. These co-authors appeared consistently alongside Gary H. Posner on published works, suggesting ongoing research partnerships.

Publications were predominantly found in the Journal of Biological Chemistry, which housed their most recognized work. The total number of published works in this venue was recorded as one.

Best Publications

  • A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure.

    Yuesheng Zhang;Paul Talalay;Cheon Gyu Cho;Gary H. Posner

  • Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates.

    Yuesheng Zhang;Thomas W. Kensler;Cheon Gyu Cho;Gary H. Posner

  • A medicinal chemistry perspective on artemisinin and related endoperoxides.

    Paul M. O'neill;Gary H. Posner

  • New stereospecific synthesis of trisubstituted olefins. Stereospecific synthesis of farnesol

    Elias J. Corey;John A. Katzenellenbogen;Gary H. Posner

  • Organic Reactions at Alumina Surfaces

    Gary H. Posner

  • Diels-Alder cycloadditions of 2-pyrones and 2-pyridones

    Kamyar Afarinkia;Victoria Vinader;Todd D. Nelson;Gary H. Posner

  • Organic reactions at alumina surfaces. Mild and selective opening of epoxides by alcohols, thiols, benzeneselenol, amines, and acetic acid

    Gary H. Posner;D. Z. Rogers

  • Antimalarial Activity of Artemisinin (Qinghaosu) and Related Trioxanes: Mechanism (s) of Action

    Jared N. Cumming;Poonsakdi Ploypradith;Gary H. Posner

  • Selective formation of carbon-carbon bonds between unlike groups using organocopper reagents

    Elias J. Corey;Gary H. Posner

  • New class of mixed cuprate(I) reagents, lithium hetero(alkyl) cuprate(I), which allow selective alkyl group transfer

    Gary H. Posner;Charles E. Whitten;Jeffrey J. Sterling

  • A convenient, one-step, high-yield replacement of an anomeric hydroxyl group by a fluorine atom using dast. Preparation of glycosyl fluorides.

    Gary H. Posner;Stephen R. Haines

  • Regiospecifically oxygen-18 labeled 1,2,4-trioxane: a simple chemical model system to probe the mechanism(s) for the antimalarial activity of artemisinin (qinghaosu).

    Gary H. Posner;Chang Ho Oh

  • Mechanism-based design, synthesis, and in vitro antimalarial testing of new 4-methylated trioxanes structurally related to artemisinin: the importance of a carbon-centered radical for antimalarial activity.

    Gary H. Posner;Chang Ho Oh;Chang Ho Oh;Chang Ho Oh;Dasong Wang;Dasong Wang;Dasong Wang;Lucia Gerena;Lucia Gerena;Lucia Gerena

  • Evidence for Fe(IV):O in the Molecular Mechanism of Action of the Trioxane Antimalarial Artemisinin

    Gary H. Posner;Jared N. Cumming;Poonsakdi Ploypradith;Chang Ho Oh

  • Orally active, antimalarial, anticancer, artemisinin-derived trioxane dimers with high stability and efficacy.

    Gary H. Posner;Ik Hyeon Paik;Surojit Sur;Andrew J. McRiner

  • Knowledge of the proposed chemical mechanism of action and cytochrome p450 metabolism of antimalarial trioxanes like artemisinin allows rational design of new antimalarial peroxides.

    Gary H Posner;Paul M O'Neill

  • Spectroscopic quantitation of organic isothiocyanates by cyclocondensation with vicinal dithiols.

    Yuesheng Zhang;Cheon Gyu Cho;Gary H. Posner;Paul Talalay

  • Asymmetric synthesis of carbon-carbon bonds using sulfinyl cycloalkenones, alkenolides, and pyrones

    Gary H. Posner

  • Design and synthesis of bifunctional isothiocyanate analogs of sulforaphane: Correlation between structure and potency as inducers of anticarcinogenic detoxication enzymes

    Gary H. Posner;Cheon Gyu Cho;Julianne V. Green;Yuesheng Zhang

  • Carbon-carbon bond formation by selective coupling of n-alkylcopper reagents with organic halides

    Elias J. Corey;Gary H. Posner

Frequent Co-Authors

Thomas W. Kensler
Thomas W. Kensler Johns Hopkins University
Maxime A. Siegler
Maxime A. Siegler Johns Hopkins University
Paul M. O'Neill
Paul M. O'Neill University of Liverpool
Wilbur K. Milhous
Wilbur K. Milhous Clemson University
David J. Sullivan
David J. Sullivan Johns Hopkins University
Zvi Schwartz
Zvi Schwartz Virginia Commonwealth University
Curt I. Civin
Curt I. Civin University of Maryland, Baltimore
Stephen A. Ward
Stephen A. Ward Liverpool School of Tropical Medicine
E. J. Corey
E. J. Corey Harvard University
Steven R. Meshnick
Steven R. Meshnick University of North Carolina at Chapel Hill

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