World's Best Scientists 2026 revealed!

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Biology and Biochemistry

D-Index
76
Citations
24221
World Ranking
4988
National Ranking
2396

Medicine

D-Index
77
Citations
24511
World Ranking
18352
National Ranking
9161

Research.com Recognitions

  • 2009 - Karl Landsteiner Memorial Award, American Association of Blood Banks (AABB)

Overview

Curt I. Civin is affiliated with the University of Maryland, Baltimore in the United States. Their research spans multiple areas within medicine and biochemistry, genetics, and molecular biology. Key subfields include molecular biology, hematology, genetics, oncology, and infectious diseases.

The scientist's recent publications reflect a focus on acute myeloid leukemia (AML), protein degradation, and inhibitors, among other topics. Notable recent papers include:

  • Venetoclax and pegcrisantaspase for complex karyotype acute myeloid leukemia, 2020, Leukemia
  • Antileukemic efficacy of a potent artemisinin combined with sorafenib and venetoclax, 2021, Blood Advances
  • Comparative efficacy and mechanism of action of cardiac progenitor cells after cardiac injury, 2022, iScience
  • The polypharmacy combination of the BCL-2 inhibitor venetoclax (VEN) and the FLT3 inhibitor gilteritinib (GIL) is more active in acute myeloid leukemia cells than novel polypharmacologic BCL-2/FLT3 VEN-GIL hybrid single-molecule inhibitors, 2024, European Journal of Medicinal Chemistry
  • A Novel 2-Carbon-Linked Dimeric Artemisinin With Potent Antileukemic Activity and Favorable Pharmacology, 2022, Frontiers in Oncology

Their primary research topics include:

  • Acute Myeloid Leukemia Research
  • Protein Degradation and Inhibitors
  • Histone Deacetylase Inhibitors Research
  • CAR-T cell therapy research
  • HIV/AIDS drug development and treatment
  • Extracellular vesicles in disease
  • Mesenchymal stem cell research

Frequent coauthors working with Curt I. Civin include Blake S. Moses, Rena G. Lapidus, Christian Eberly, Bryan T. Mott, and Michelle A. Rudek.

They have published in various journals such as Leukemia, European Journal of Medicinal Chemistry, Blood Advances, Frontiers in Oncology, and iScience.

Curt I. Civin received the Karl Landsteiner Memorial Award from the American Association of Blood Banks (AABB) in 2009.

Best Publications

  • Antigenic analysis of hematopoiesis. III. A hematopoietic progenitor cell surface antigen defined by a monoclonal antibody raised against KG-1a cells.

    C I Civin;L C Strauss;C Brovall;M J Fackler

  • CD34 : structure, biology, and clinical utility

    DS Krause;MJ Fackler;CI Civin;WS May

  • Characterization of clonogenic multiple myeloma cells

    William H Matsui;Carol Ann Huff;Qiuju Wang;Matthew T Malehorn

  • The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB–binding protein

    Julian Borrow;Vincent P. Stanton;J. Michael Andresen;Reinhard Becher

  • CD34+ hematopoietic stem-progenitor cell microRNA expression and function: a circuit diagram of differentiation control.

    Robert W. Georgantas;Richard Hildreth;Sebastien Morisot;Jonathan Alder

  • Flow cytometric analysis of human bone marrow. II. Normal B lymphocyte development.

    Michael R. Loken;Virendra O. Shah;Virendra O. Shah;Karen L. Dattilio;Karen L. Dattilio;Curt I. Civin;Curt I. Civin

  • Distinct Patterns of Inactivation of p15INK4B and p16INK4A Characterize the Major Types of Hematological Malignancies

    James G. Herman;Curt I. Civin;Jean Pierre J. Issa;Michael I. Collector

  • A novel temporal expression pattern of three C/EBP family members in differentiating myelomonocytic cells.

    Linda M. Scott;Curt I. Civin;Pernille Rorth;Alan D. Friedman

  • Flow cytometric analysis of human bone marrow: I. Normal erythroid development

    Michael R. Loken;Michael R. Loken;Virendra O. Shah;Virendra O. Shah;Karen L. Dattilio;Karen L. Dattilio;Curt I. Civin;Curt I. Civin

  • Hematopoietic differentiation of human embryonic stem cells progresses through sequential hematoendothelial, primitive, and definitive stages resembling human yolk sac development

    Elias T. Zambidis;Bruno Peault;Tea Soon Park;Tea Soon Park;Fred Bunz;Fred Bunz

  • Direct demonstration of elevated aldehyde dehydrogenase in human hematopoietic progenitor cells

    MB Kastan;E Schlaffer;JE Russo;OM Colvin

  • Expression of the hematopoietic growth factor receptor FLT3 (STK-1/Flk2) in human leukemias.

    Catherine E. Carow;Mark Levenstein;Scott H. Kaufmann;Joseph Chen

  • Human stem cells

    Curt I. Civin

  • Cotransplantation of human mesenchymal stem cells enhances human myelopoiesis and megakaryocytopoiesis in NOD/SCID mice.

    Maria Angelopoulou;Enrico Novelli;Joanna E Grove;Henry M Rinder

  • Purification of human erythroid colony-forming units and demonstration of specific binding of erythropoietin.

    K Sawada;S B Krantz;J S Kans;E N Dessypris

  • Mobile Interspersed Repeats Are Major Structural Variants in the Human Genome

    Cheng Ran Lisa Huang;Anna M. Schneider;Yunqi Lu;Tejasvi Niranjan

  • Sustained, retransplantable, multilineage engraftment of highly purified adult human bone marrow stem cells in vivo

    Curt I. Civin;Grace Almeida-Porada;Mi Jeong Lee;Johanna Olweus

  • Notch inhibits Ptf1 function and acinar cell differentiation in developing mouse and zebrafish pancreas

    Farzad Esni;Bidyut Ghosh;Andrew V. Biankin;John W. Lin

  • Kruppel-Like Factor 4 Is Essential for Inflammatory Monocyte Differentiation In Vivo

    Jonathan K. Alder;Robert W. Georgantas;Richard L. Hildreth;Ian M. Kaplan

  • Prognostic importance of immunophenotyping in adults with acute myelocytic leukaemia: the significance of the stem‐cell glycoprotein CD34 (My 10)

    Robert B. Geller;Marianna Zahurak;Craig A. Hurwitz;Philip J. Burke

Frequent Co-Authors

Donald Small
Donald Small Johns Hopkins University
Michael R. Loken
Michael R. Loken Fred Hutchinson Cancer Research Center
Linzhao Cheng
Linzhao Cheng Chinese Academy of Sciences
Alan D. Friedman
Alan D. Friedman Johns Hopkins University
Michael B. Kastan
Michael B. Kastan Duke University
Armand Bensussan
Armand Bensussan Hôpital Saint-Louis
Christopher D. Buckley
Christopher D. Buckley University of Oxford
Stefan Meuer
Stefan Meuer Heidelberg University
James H. Morrissey
James H. Morrissey University of Michigan–Ann Arbor
Eric Vivier
Eric Vivier Aix-Marseille University

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