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Leon W.M.M. Terstappen

Leon W.M.M. Terstappen

D-Index & Metrics

Medicine

D-Index
95
Citations
43972
World Ranking
9908
National Ranking
387

Overview

Leon W.M.M. Terstappen is affiliated with the University of Twente in the Netherlands. Their research primarily spans the fields of Medicine and Biochemistry, Genetics, and Molecular Biology. Their work frequently intersects with oncology, cancer research, molecular biology, biomedical engineering, and pulmonary and respiratory medicine as key subfields.

The scientist's research topics cover a range of areas related to cancer biology and diagnostics. These include:

  • Cancer Cells and Metastasis
  • Cancer Genomics and Diagnostics
  • Extracellular vesicles in disease
  • Prostate Cancer Treatment and Research
  • Microfluidic and Bio-sensing Technologies
  • MicroRNA in disease regulation
  • Microfluidic and Capillary Electrophoresis Applications

Frequent publication venues for their research are:

  • Cancers
  • Cancer Research
  • Molecular Oncology
  • Communications Biology
  • British Journal of Cancer

Among the more recent scientific papers authored or co-authored by Terstappen are:

  • "Deep learning of circulating tumour cells," 2020, Nature Machine Intelligence
  • "Tumour-derived extracellular vesicles in blood of metastatic cancer patients associate with overall survival," 2020, British Journal of Cancer
  • "Genetic characterization of a unique neuroendocrine transdifferentiation prostate circulating tumor cell-derived eXplant model," 2020, Nature Communications
  • "StarDist Image Segmentation Improves Circulating Tumor Cell Detection," 2022, Cancers
  • "Reconstructing single-cell karyotype alterations in colorectal cancer identifies punctuated and gradual diversification patterns," 2021, Nature Genetics

The researcher collaborates frequently with several colleagues, including:

  • Afroditi Nanou
  • Michiel Stevens
  • Anouk Mentink
  • Ruchi Bansal
  • Frank Coumans

Best Publications

  • Circulating Tumor Cells, Disease Progression, and Survival in Metastatic Breast Cancer

    Massimo Cristofanilli;G. Thomas Budd;Matthew J. Ellis;Alison Stopeck

  • Tumor cells circulate in the peripheral blood of all major carcinomas but not in healthy subjects or patients with nonmalignant diseases.

    W. Jeffrey Allard;Jeri Matera;M. Craig Miller;Madeline Repollet

  • Relationship of Circulating Tumor Cells to Tumor Response, Progression-Free Survival, and Overall Survival in Patients With Metastatic Colorectal Cancer

    Steven J. Cohen;Cornelis J.A. Punt;Nicholas Iannotti;Bruce H. Saidman

  • Circulating Tumor Cells: A Novel Prognostic Factor for Newly Diagnosed Metastatic Breast Cancer

    Massimo Cristofanilli;Daniel F. Hayes;G. Thomas Budd;Mathew J. Ellis

  • Circulating Tumor Cells at Each Follow-up Time Point during Therapy of Metastatic Breast Cancer Patients Predict Progression-Free and Overall Survival

    Daniel F. Hayes;Massimo Cristofanilli;G. Thomas Budd;Matthew J. Ellis

  • Circulating tumor cells in patients with breast cancer dormancy

    Songdong Meng;Debasish Tripathy;Eugene P. Frenkel;Sanjay Shete

  • Sequential generations of hematopoietic colonies derived from single nonlineage-committed CD34+CD38- progenitor cells.

    Leon W.M.M. Terstappen;Shiang Huang;Meredith Safford;Peter M. Lansdorp

  • Circulating Tumor Cells versus Imaging—Predicting Overall Survival in Metastatic Breast Cancer

    G. Thomas Budd;Massimo Cristofanilli;Mathew J. Ellis;Allison Stopeck

  • Detection and characterization of carcinoma cells in the blood

    Emilian Racila;David Euhus;Arthur J. Weiss;Chandra Rao

  • Significance of Circulating Tumor Cells Detected by the CellSearch System in Patients with Metastatic Breast Colorectal and Prostate Cancer.

    M. Craig Miller;Gerald V. Doyle;Leon W. M. M Terstappen

  • Characterization of ERG, AR and PTEN Gene Status in Circulating Tumor Cells from Patients with Castration-Resistant Prostate Cancer

    Gerhardt Attard;Joost F. Swennenhuis;David Olmos;Alison H.M. Reid

  • HER-2 gene amplification can be acquired as breast cancer progresses.

    Songdong Meng;Debasish Tripathy;Sanjay Shete;Raheela Ashfaq

  • Prognostic significance of circulating tumor cells in patients with metastatic colorectal cancer.

    S.J. Cohen;C.J.A. Punt;N. Iannotti;B.H. Saidman

  • Control of lymphocyte recirculation in man. II. Differential regulation of the cutaneous lymphocyte-associated antigen, a tissue-selective homing receptor for skin-homing T cells.

    L. J. Picker;J. R. Treer;B. Ferguson-Darnell;P. A. Collins

  • Methods and reagents for the rapid and efficient isolation of circulating cancer cells

    Leon W. M. M. Terstappen;Galla Chandra Rao;Jonathan W. Uhr;Emilian V. Racila

  • Control of lymphocyte recirculation in man. I. Differential regulation of the peripheral lymph node homing receptor L-selectin on T cells during the virgin to memory cell transition.

    L. J. Picker;J. R. Treer;B. Ferguson-Darnell;P. A. Collins

  • Significant and Sustained Antitumor Activity in Post-Docetaxel, Castration-Resistant Prostate Cancer With the CYP17 Inhibitor Abiraterone Acetate

    Alison H.M. Reid;Gerhardt Attard;Daniel C. Danila;Nikhil Babu Oommen

  • Expression of epithelial cell adhesion molecule in carcinoma cells present in blood and primary and metastatic tumors

    Chandra G. Rao;David Chianese;Gerald V. Doyle;M. Craig Miller

  • Rapid selection of cell subpopulation-specific human monoclonal antibodies from a synthetic phage antibody library.

    J de Kruif;L Terstappen;E Boel;T Logtenberg

  • Circulating tumor cell analysis in patients with progressive castration-resistant prostate cancer

    David R Shaffer;Margaret A Leversha;Daniel C Danila;Oscar Lin

Frequent Co-Authors

Michael R. Loken
Michael R. Loken Fred Hutchinson Cancer Research Center
Johann S. de Bono
Johann S. de Bono Institute of Cancer Research
Harry J.M. Groen
Harry J.M. Groen University Medical Center Groningen
Gerhardt Attard
Gerhardt Attard University College London
Klaus Pantel
Klaus Pantel Universität Hamburg
Stefan Sleijfer
Stefan Sleijfer Erasmus University Rotterdam
Massimo Cristofanilli
Massimo Cristofanilli Cornell University
Tanja Fehm
Tanja Fehm Heinrich Heine University Düsseldorf
Jonathan W. Uhr
Jonathan W. Uhr The University of Texas Southwestern Medical Center
Daniel F. Hayes
Daniel F. Hayes University of Michigan–Ann Arbor

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