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D-Index & Metrics

Biology and Biochemistry

D-Index
137
Citations
80926
World Ranking
322
National Ranking
216

Research.com Recognitions

  • 2017 - Member of the National Academy of Engineering For engineering novel microelectromechanical and microfluidic point-of-care devices that improve detection of cancer, prenatal genetic defects, and infectious disease.
  • 2016 - Fellow, National Academy of Inventors
  • 2007 - Fellow of the American Society of Mechanical Engineers
  • 1999 - Fellow of the Indian National Academy of Engineering (INAE)

Overview

Mehmet Toner is affiliated with Harvard University in the United States and has contributed extensively to research in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans several subfields, including Biomedical Engineering, Cancer Research, Oncology, Molecular Biology, and Surgery.

The scientist's research focuses on areas such as Microfluidic and Bio-sensing Technologies, Organ Transplantation Techniques and Outcomes, Cancer Cells and Metastasis, Cancer Genomics and Diagnostics, Liver Disease and Transplantation, Organ Donation and Transplantation, and 3D Printing in Biomedical Research.

Mehmet Toner has published papers in a range of scientific venues with several recurrent publication platforms including Cryobiology, bioRxiv (Cold Spring Harbor Laboratory), Scientific Reports, American Journal of Transplantation, and Cancer Research.

  • Deregulation of ribosomal protein expression and translation promotes breast cancer metastasis (2020) in Science
  • The Lipogenic Regulator SREBP2 Induces Transferrin in Circulating Melanoma Cells and Suppresses Ferroptosis (2020) in Cancer Discovery
  • Ultrahigh-throughput magnetic sorting of large blood volumes for epitope-agnostic isolation of circulating tumor cells (2020) in Proceedings of the National Academy of Sciences
  • HIF1A signaling selectively supports proliferation of breast cancer in the brain (2020) in Nature Communications
  • Microfluidic concentration and separation of circulating tumor cell clusters from large blood volumes (2020) in Lab on a Chip

Frequent collaborators of Mehmet Toner have included Shyamala Maheswaran, Shannon N. Tessier, Daniel A. Haber, Korkut Uygun, and Rebecca D. Sandlin, reflecting a sustained network of co-authorship in the field.

Throughout their career, Mehmet Toner has received several recognitions such as being named a Member of the National Academy of Engineering in 2017 for contributions to engineering novel microelectromechanical and microfluidic point-of-care devices impacting cancer detection, prenatal genetic defects, and infectious diseases.

  • Fellow, National Academy of Inventors (2016)
  • Fellow of the American Society of Mechanical Engineers (2007)
  • Fellow of the Indian National Academy of Engineering (INAE) (1999)

Best Publications

  • Isolation of rare circulating tumour cells in cancer patients by microchip technology.

    Sunitha Nagrath;Lecia V. Sequist;Shyamala Maheswaran;Daphne W. Bell;Daphne W. Bell

  • Circulating Breast Tumor Cells Exhibit Dynamic Changes in Epithelial and Mesenchymal Composition

    Min Yu;Aditya Bardia;Ben S. Wittner;Shannon L. Stott

  • Circulating Tumor Cell Clusters Are Oligoclonal Precursors of Breast Cancer Metastasis

    Nicola Aceto;Aditya Bardia;David T. Miyamoto;Maria C. Donaldson

  • Detection of Mutations in EGFR in Circulating Lung-Cancer Cells

    Shyamala Maheswaran;Lecia V. Sequist;Sunitha Nagrath;Lindsey Ulkus

  • Continuous inertial focusing, ordering, and separation of particles in microchannels

    Dino Di Carlo;Daniel Irimia;Ronald G. Tompkins;Mehmet Toner

  • Isolation of circulating tumor cells using a microvortex-generating herringbone-chip

    Shannon L. Stott;Chia Hsien Hsu;Chia Hsien Hsu;Chia Hsien Hsu;Dina I. Tsukrov;Min Yu

  • A network-based analysis of systemic inflammation in humans

    Steve E. Calvano;Wenzhong Xiao;Daniel R. Richards;Ramon M. Felciano

  • A genomic storm in critically injured humans

    Wenzhong Xiao;Wenzhong Xiao;Michael N. Mindrinos;Junhee Seok;Joseph Cuschieri

  • Circulating tumor cells: approaches to isolation and characterization

    Min Yu;Shannon Stott;Mehmet Toner;Shyamala Maheswaran

  • Inertial Focusing for Tumor Antigen–Dependent and –Independent Sorting of Rare Circulating Tumor Cells

    Emre Ozkumur;Ajay M. Shah;Jordan C. Ciciliano;Benjamin L. Emmink

  • Neutrophil chemotaxis in linear and complex gradients of interleukin-8 formed in a microfabricated device

    Noo Li Jeon;Harihara Baskaran;Stephan K. W. Dertinger;George M. Whitesides

  • Effect of cell–cell interactions in preservation of cellular phenotype: cocultivation of hepatocytes and nonparenchymal cells

    S. N. Bhatia;U. J. Balis;M. L. Yarmush;M. Toner

  • Ex vivo culture of circulating breast tumor cells for individualized testing of drug susceptibility

    Min Yu;Min Yu;Aditya Bardia;Nicola Aceto;Francesca Bersani

  • Multifunctional encoded particles for high-throughput biomolecule analysis.

    Daniel C. Pregibon;Mehmet Toner;Patrick S. Doyle

  • Blood-on-a-Chip

    Mehmet Toner;Daniel Irimia

  • Microfluidic, marker-free isolation of circulating tumor cells from blood samples

    Nezihi Murat Karabacak;Philipp S Spuhler;Fabio Fachin;Eugene J Lim

  • Microengineering of Cellular Interactions

    Albert Folch;Mehmet Toner

  • Long-term storage of tissues by cryopreservation: critical issues

    Jens O.M. Karlsson;Mehmet Toner

  • A microfluidic device for label-free, physical capture of circulating tumor cell clusters

    A Fatih Sarioglu;Nicola Aceto;Nikola Kojic;Maria C Donaldson

  • Engineering complex tissues.

    Antonios G. Mikos;Susan W. Herring;Pannee Ochareon;Jennifer Elisseeff

Frequent Co-Authors

Martin L. Yarmush
Martin L. Yarmush Rutgers, The State University of New Jersey
Daniel A. Haber
Daniel A. Haber Harvard University
Ronald G. Tompkins
Ronald G. Tompkins Harvard University
Shyamala Maheswaran
Shyamala Maheswaran Harvard University
Daniel Irimia
Daniel Irimia Harvard University
David T. Ting
David T. Ting Harvard University
Lecia V. Sequist
Lecia V. Sequist Harvard University
Sridhar Ramaswamy
Sridhar Ramaswamy Harvard University
John D. Biggers
John D. Biggers Harvard University
Aditya Bardia
Aditya Bardia Harvard University

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