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Biology and Biochemistry

D-Index
65
Citations
11729
World Ranking
9386
National Ranking
4137

Overview

Louise C. Showe is affiliated with The Wistar Institute in the United States. Their research spans multiple disciplines within medicine and biochemistry, genetics, and molecular biology.

The scientist's main fields of study include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Subfields of their work cover:

  • Molecular Biology
  • Immunology
  • Cancer Research
  • Oncology
  • Pathology and Forensic Medicine

Key research topics associated with their publications include:

  • Viral-associated cancers and disorders
  • Machine Learning in Bioinformatics
  • Gene expression and cancer classification
  • MicroRNA in disease regulation
  • Lymphoma Diagnosis and Treatment
  • Cutaneous lymphoproliferative disorders research
  • T-cell and Retrovirus Studies

Among their recent papers are:

  • Epigenetic specifications of host chromosome docking sites for latent Epstein-Barr virus, 2020, Nature Communications
  • A multi-omics approach to Epstein-Barr virus immortalization of B-cells reveals EBNA1 chromatin pioneering activities targeting nucleotide metabolism, 2021, PLoS Pathogens
  • Recursive Cluster Elimination based Rank Function (SVM-RCE-R) implemented in KNIME, 2021, F1000Research
  • GediNET for discovering gene associations across diseases using knowledge based machine learning approach, 2022, Scientific Reports
  • Telomere dysfunction implicates POT1 in patients with idiopathic pulmonary fibrosis, 2022, The Journal of Experimental Medicine

Frequent co-authors in their publications include:

  • Andrew V. Kossenkov (8 collaborations)
  • Malik Yousef (4 collaborations)
  • Bruno Gran (3 collaborations)
  • Cris S. Constantinescu (3 collaborations)
  • Fang Lü (2 collaborations)

Their work has appeared in multiple research venues with a concentration in:

  • F1000Research (2 publications)
  • Nature Communications
  • PLoS Pathogens
  • Scientific Reports
  • The Journal of Experimental Medicine

Best Publications

  • Immunopathogenesis and therapy of cutaneous T cell lymphoma

    Ellen J. Kim;Stephen Hess;Stephen K. Richardson;Sara Newton

  • Analysis of genomic targets reveals complex functions of MYC

    Jagruti H. Patel;Andrey P. Loboda;Michael K. Showe;Louise C. Showe

  • Cutting Edge: Differentiation of Human NK Cells into NK1 and NK2 Subsets

    David Peritt;Susan Robertson;Giorgia Gri;Louise Showe

  • Editing of Epstein-Barr Virus-encoded BART6 MicroRNAs Controls Their Dicer Targeting and Consequently Affects Viral Latency

    Hisashi Iizasa;Bjorn-Erik Wulff;Nageswara R. Alla;Manolis Maragkakis

  • Classification and Prediction of Survival in Patients with the Leukemic Phase of Cutaneous T Cell Lymphoma

    Laszlo Kari;Andrey Loboda;Michael Nebozhyn;Alain H. Rook

  • A common mechanism of chromosomal translocation in T- and B-cell neoplasia.

    Lawrence R. Finger;Richard C. Harvey;Robert C. A. Moore;Louise C. Showe

  • Combining multi-species genomic data for microRNA identification using a Naïve Bayes classifier

    Malik Yousef;Michael Nebozhyn;Hagit Shatkay;Stathis Kanterakis

  • c-Myc induces apoptosis in epithelial cells by both p53-dependent and p53-independent mechanisms.

    Daitoku Sakamuro;Valerie Eviner;Katherine J. Elliott;Katherine J. Elliott;Louise Showe

  • Transforming Growth Factor-β1 Increases Survival of Human Melanoma through Stroma Remodeling

    Carola Berking;Richelle Takemoto;Helmut Schaider;Louise Showe

  • Alternative transcription exceeds alternative splicing in generating the transcriptome diversity of cerebellar development

    Sharmistha Pal;Ravi Gupta;Hyunsoo Kim;Priyankara Wickramasinghe

  • KLF17 is a negative regulator of epithelial–mesenchymal transition and metastasis in breast cancer

    Kiranmai Gumireddy;Anping Li;Phyllis A. Gimotty;Andres J. Klein-Szanto

  • Naïve Bayes for microRNA target predictions—machine learning for microRNA targets

    Malik Yousef;Segun Jung;Andrew V. Kossenkov;Louise C. Showe

  • The p130 Isoform of Angiomotin Is Required for Yap-Mediated Hepatic Epithelial Cell Proliferation and Tumorigenesis

    Chunling Yi;Zhewei Shen;Anat Stemmer-Rachamimov;Noor Dawany

  • Gene expression profiles in peripheral blood mononuclear cells can distinguish patients with non-small cell lung cancer from patients with nonmalignant lung disease.

    Michael K. Showe;Anil Vachani;Andrew V. Kossenkov;Malik Yousef

  • Cloning and structural characterization of a human non-erythroid band 3-like protein

    D.R. Demuth;L.C. Showe;M. Ballantine;A. Palumbo

  • Molecular cloning and nucleotide sequence of a full-length cDNA for human alpha enolase.

    Agata Giallongo;Salvatore Feo;Robert Moore;Carlo M. Croce

  • The mRNA-edited form of GABRA3 suppresses GABRA3-mediated Akt activation and breast cancer metastasis

    Kiranmai Gumireddy;Anping Li;Andrew V. Kossenkov;Masayuki Sakurai

  • Increased programmed death-1 expression on CD4+ T cells in cutaneous T-cell lymphoma: implications for immune suppression.

    Sara Samimi;Bernice Benoit;Katherine Evans;E. John Wherry

  • Microarray data on gene modulation by HIV-1 in immune cells: 2000-2006.

    Malavika S. Giri;Malavika S. Giri;Michael Nebozhyn;Louise Showe;Luis J. Montaner

  • Learning from positive examples when the negative class is undetermined--microRNA gene identification.

    Malik Yousef;Segun Jung;Segun Jung;Louise C Showe;Michael K Showe

Frequent Co-Authors

Andrew V. Kossenkov
Andrew V. Kossenkov The Wistar Institute
Maria Wysocka
Maria Wysocka University of Pennsylvania
Luis J. Montaner
Luis J. Montaner The Wistar Institute
Paul M. Lieberman
Paul M. Lieberman The Wistar Institute
Ramana V. Davuluri
Ramana V. Davuluri Stony Brook University
Giorgio Trinchieri
Giorgio Trinchieri National Institutes of Health
Brian M. Barnes
Brian M. Barnes University of Alaska Fairbanks
Steven M. Albelda
Steven M. Albelda University of Pennsylvania
Lin Zhang
Lin Zhang University of Pennsylvania
Carlo M. Croce
Carlo M. Croce The Ohio State University

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