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Andrew V. Kossenkov

Andrew V. Kossenkov

D-Index & Metrics

Biology and Biochemistry

D-Index
76
Citations
19506
World Ranking
5078
National Ranking
2432

Overview

Andrew V. Kossenkov is affiliated with The Wistar Institute in the United States. Their research spans multiple fields including Biochemistry, Genetics and Molecular Biology, Medicine, and Immunology and Microbiology. Within these domains, Kossenkov has a significant focus on Molecular Biology, Immunology, Oncology, Cancer Research, and Pulmonary and Respiratory Medicine.

The scientist's work centers on topics related to the role and behavior of immune cells in cancer, viral-associated cancers and disorders, cancer-related hypoxia and metabolism, RNA modifications, immune cell function and interaction, HIV research, as well as epigenetics and DNA methylation.

Recent publications by Andrew V. Kossenkov include the following papers:

  • "Ferroptosis of tumour neutrophils causes immune suppression in cancer," 2022, Nature
  • "Analysis of classical neutrophils and polymorphonuclear myeloid-derived suppressor cells in cancer patients and tumor-bearing mice," 2021, The Journal of Experimental Medicine
  • "The microbiome-derived metabolite TMAO drives immune activation and boosts responses to immune checkpoint blockade in pancreatic cancer," 2022, Science Immunology
  • "Reactivation of dormant tumor cells by modified lipids derived from stress-activated neutrophils," 2020, Science Translational Medicine
  • "Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts," 2021, Nature Genetics

Frequent coauthors collaborating with Kossenkov include Qin Liu, Toshitha Kannan, Hsin-Yao Tang, Rugang Zhang, and David W. Speicher.

Kossenkov's research has been published predominantly in specialized and high-impact venues including:

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Nature
  • PLoS Pathogens

Best Publications

  • Lectin-type oxidized LDL receptor-1 distinguishes population of human polymorphonuclear myeloid-derived suppressor cells in cancer patients

    Thomas Condamine;George A. Dominguez;Je-In Youn;Andrew V. Kossenkov

  • Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A -mutated cancers

    Benjamin G. Bitler;Katherine M. Aird;Azat Garipov;Hua Li

  • Fatty acid transport protein 2 reprograms neutrophils in cancer

    Filippo Veglia;Vladimir A. Tyurin;Maria Blasi;Alessandra De Leo

  • BET Bromodomain Inhibition Promotes Anti-tumor Immunity by Suppressing PD-L1 Expression.

    Hengrui Zhu;Fee Bengsch;Nikolaos Svoronos;Melanie R. Rutkowski

  • IRE1α–XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity

    Minkyung Song;Tito A. Sandoval;Chang-Suk Chae;Sahil Chopra

  • sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance

    Amanpreet Kaur;Amanpreet Kaur;Marie R. Webster;Katie Marchbank;Reeti Behera

  • Remodeling of the Collagen Matrix in Aging Skin Promotes Melanoma Metastasis and Affects Immune Cell Motility

    Amanpreet Kaur;Amanpreet Kaur;Amanpreet Kaur;Brett L. Ecker;Stephen M. Douglass;Curtis H. Kugel

  • NAD+ metabolism governs the proinflammatory senescence-associated secretome

    Timothy Nacarelli;Lena Lau;Takeshi Fukumoto;Joseph Zundell

  • Unlinking an lncRNA from Its Associated cis Element

    Vikram R. Paralkar;Cristian C. Taborda;Peng Huang;Yu Yao

  • ARID1A -mutated ovarian cancers depend on HDAC6 activity

    Benjamin G. Bitler;Shuai Wu;Pyoung Hwa Park;Yang Hai

  • PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion

    M. Cecilia Caino;Jagadish C. Ghosh;Young Chan Chae;Valentina Vaira

  • Recent Advances Targeting CCR5 for Cancer and Its Role in Immuno-Oncology.

    Xuanmao Jiao;Omar Nawab;Tejal Patel;Andrew V. Kossenkov

  • ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression.

    Feven Tameire;Ioannis I Verginadis;Nektaria Maria Leli;Christine Polte

  • Naïve Bayes for microRNA target predictions—machine learning for microRNA targets

    Malik Yousef;Segun Jung;Andrew V. Kossenkov;Louise C. Showe

  • Mitochondrial Akt Regulation of Hypoxic Tumor Reprogramming

    Young Chan Chae;Valentina Vaira;Valentina Vaira;M. Cecilia Caino;Hsin Yao Tang

  • Gene expression profiles in peripheral blood mononuclear cells can distinguish patients with non-small cell lung cancer from patients with nonmalignant lung disease.

    Michael K. Showe;Anil Vachani;Andrew V. Kossenkov;Malik Yousef

  • Lineage and species-specific long noncoding RNAs during erythro-megakaryocytic development.

    Vikram R. Paralkar;Tejaswini Mishra;Jing Luan;Yu Yao

  • Unique pattern of neutrophil migration and function during tumor progression.

    Sima Patel;Sima Patel;Shuyu Fu;Shuyu Fu;Jerome Mastio;George A Dominguez

  • Analysis of classical neutrophils and polymorphonuclear myeloid-derived suppressor cells in cancer patients and tumor-bearing mice

    Filippo Veglia;Ayumi Hashimoto;Harsh Dweep;Emilio Sanseviero

  • Landscape of the mitochondrial Hsp90 metabolome in tumours.

    Young Chan Chae;Alessia Angelin;Sofia Lisanti;Andrew V. Kossenkov

Frequent Co-Authors

Louise C. Showe
Louise C. Showe The Wistar Institute
David W. Speicher
David W. Speicher The Wistar Institute
Lucia R. Languino
Lucia R. Languino Thomas Jefferson University
Rugang Zhang
Rugang Zhang The Wistar Institute
Dario C. Altieri
Dario C. Altieri The Wistar Institute
Dmitry I. Gabrilovich
Dmitry I. Gabrilovich AstraZeneca (United Kingdom)
Paul M. Lieberman
Paul M. Lieberman The Wistar Institute
Ashani T. Weeraratna
Ashani T. Weeraratna Johns Hopkins University
Maureen E. Murphy
Maureen E. Murphy The Wistar Institute
Xiaowei Xu
Xiaowei Xu University of Pennsylvania

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