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Jose R. Conejo-Garcia

Jose R. Conejo-Garcia

D-Index & Metrics

Immunology

D-Index
76
Citations
29108
World Ranking
1866
National Ranking
910

Overview

Jose R. Conejo-Garcia is affiliated with Duke University in the United States and has extensive research contributions primarily in the fields of Medicine, Immunology and Microbiology, and Biochemistry, Genetics, and Molecular Biology. Their work spans significant subfields such as Immunology, Oncology, Molecular Biology, Cancer Research, and Radiology, Nuclear Medicine, and Imaging.

Their research topics cover a range of areas focused on cancer and immune system interactions, including:

  • Cancer Immunotherapy and Biomarkers
  • Immunotherapy and Immune Responses
  • Immune Cell Function and Interaction
  • CAR-T cell therapy research
  • Immune cells in cancer
  • Monoclonal and Polyclonal Antibodies Research
  • Ovarian cancer diagnosis and treatment

Jose R. Conejo-Garcia has published research in a variety of journals with multiple papers appearing in leading venues such as Cancer Research, Journal of Clinical Oncology, and The Journal of Immunology. They also have a notable presence in Regular and Young Investigator Award Abstracts and bioRxiv (Cold Spring Harbor Laboratory).

Frequent co-authors include:

  • Paulo C. Rodrı́guez
  • Xiaoqing Yu
  • Subir Biswas
  • Carmen M. Anadon
  • Jessica A. Mine

Key recent publications by Jose R. Conejo-Garcia include:

  • "Tumor-infiltrating lymphocyte treatment for anti-PD-1-resistant metastatic lung cancer: a phase 1 trial" (2021) published in Nature Medicine
  • "Tumor interferon signaling and suppressive myeloid cells are associated with CAR T-cell failure in large B-cell lymphoma" (2021) published in Blood
  • "IgA transcytosis and antigen recognition govern ovarian cancer immunity" (2021) published in Nature
  • "The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling" (2020) published in Immunity
  • "Glucose-driven histone lactylation promotes the immunosuppressive activity of monocyte-derived macrophages in glioblastoma" (2024) published in Immunity

Best Publications

  • Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival.

    Tyler J Curiel;George Coukos;Linhua Zou;Xavier Alvarez

  • Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer.

    Lin Zhang;Jose R. Conejo-Garcia;Dionyssios Katsaros;Phyllis A. Gimotty

  • ER Stress Sensor XBP1 Controls Anti-tumor Immunity by Disrupting Dendritic Cell Homeostasis

    Juan R. Cubillos-Ruiz;Pedro C. Silberman;Melanie R. Rutkowski;Sahil Chopra

  • Cooperation between Constitutive and Inducible Chemokines Enables T Cell Engraftment and Immune Attack in Solid Tumors

    Denarda Dangaj;Marine Bruand;Alizée J. Grimm;Catherine Ronet

  • Tumor-associated neutrophils stimulate T cell responses in early-stage human lung cancer.

    Evgeniy B. Eruslanov;Pratik S. Bhojnagarwala;Jon G. Quatromoni;Tom Li Stephen

  • Tumor-infiltrating dendritic cell precursors recruited by a beta-defensin contribute to vasculogenesis under the influence of Vegf-A.

    Jose R. Conejo-Garcia;Fabian Benencia;Maria Cecilia Courreges;Eugene Kang

  • Origin and Role of a Subset of Tumor-Associated Neutrophils with Antigen-Presenting Cell Features in Early-Stage Human Lung Cancer

    Sunil Singhal;Sunil Singhal;Pratik S. Bhojnagarwala;Shaun O'Brien;Edmund K. Moon

  • Safety and Efficacy of Intratumoral Injections of Chimeric Antigen Receptor (CAR) T Cells in Metastatic Breast Cancer.

    Julia Tchou;Yangbing Zhao;Bruce L Levine;Paul J Zhang

  • BET Bromodomain Inhibition Promotes Anti-tumor Immunity by Suppressing PD-L1 Expression.

    Hengrui Zhu;Fee Bengsch;Nikolaos Svoronos;Melanie R. Rutkowski

  • IRE1α–XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity

    Minkyung Song;Tito A. Sandoval;Chang-Suk Chae;Sahil Chopra

  • Tumor-intrinsic PD-L1 signals regulate cell growth, pathogenesis and autophagy in ovarian cancer and melanoma

    Curtis A Clark;Harshita Gupta;Gangadhara R. Sareddy;Srilakshmi Pandeswara

  • Tumor-infiltrating lymphocyte treatment for anti-PD-1-resistant metastatic lung cancer: a phase 1 trial.

    Benjamin C. Creelan;Chao Wang;Jamie K. Teer;Eric M. Toloza

  • Ovarian cancer progression is controlled by phenotypic changes in dendritic cells

    Uciane K. Scarlett;Melanie R. Rutkowski;Adam M. Rauwerdink;Jennifer Fields

  • Age Correlates with Response to Anti-PD1, Reflecting Age-Related Differences in Intratumoral Effector and Regulatory T-Cell Populations

    Curtis H. Kugel;Stephen M. Douglass;Marie R. Webster;Amanpreet Kaur;Amanpreet Kaur

  • Microbially Driven TLR5-Dependent Signaling Governs Distal Malignant Progression through Tumor-Promoting Inflammation

    Melanie R. Rutkowski;Tom L. Stephen;Nikolaos Svoronos;Michael J. Allegrezza

  • Tumor interferon signaling and suppressive myeloid cells are associated with CAR T-cell failure in large B-cell lymphoma

    Michael D. Jain;Hua Zhao;Xuefeng Wang;Reginald Atkins

  • Polyethylenimine-based siRNA nanocomplexes reprogram tumor-associated dendritic cells via TLR5 to elicit therapeutic antitumor immunity

    Juan R. Cubillos-Ruiz;Xavier Engle;Uciane K. Scarlett;Diana Martinez

  • Isolation and biochemical characterization of LEAP‐2, a novel blood peptide expressed in the liver

    Alexander Krause;Rannar Sillard;Burkhard Kleemeier;Enno Klüver

  • Local hyperthermia treatment of tumors induces CD8+ T cell-mediated resistance against distal and secondary tumors

    Seiko Toraya-Brown;Mee Rie Sheen;Peisheng Zhang;Lei Chen

  • IgA transcytosis and antigen recognition govern ovarian cancer immunity.

    Subir Biswas;Gunjan Mandal;Kyle K. Payne;Carmen M. Anadon

  • Tumor Cell-Independent Estrogen Signaling Drives Disease Progression Through Mobilization of Myeloid-Derived Suppressor Cells

    Nikolaos Svoronos;Alfredo Perales-Puchalt;Michael J. Allegrezza;Melanie R. Rutkowski

  • In situ stimulation of CD40 and Toll-like receptor 3 transforms ovarian cancer-infiltrating dendritic cells from immunosuppressive to immunostimulatory cells.

    Uciane K. Scarlett;Juan R. Cubillos-Ruiz;Yolanda C. Nesbeth;Diana G. Martinez

  • Reprogramming Tumor-Associated Dendritic Cells In Vivo Using miRNA Mimetics Triggers Protective Immunity against Ovarian Cancer

    Juan R. Cubillos-Ruiz;Jason R. Baird;Amelia J. Tesone;Melanie R. Rutkowski

  • Depletion of Dendritic Cells Delays Ovarian Cancer Progression by Boosting Antitumor Immunity

    Eduardo Huarte;Juan R. Cubillos-Ruiz;Yolanda C. Nesbeth;Uciane K. Scarlett

  • Mesothelin, a novel immunotherapy target for triple negative breast cancer

    Julia Tchou;Liang-Chuan Wang;Ben Selven;Hongtao Zhang

Frequent Co-Authors

George Coukos
George Coukos Cornell University
Lin Zhang
Lin Zhang University of Pennsylvania
Rugang Zhang
Rugang Zhang The Wistar Institute
Paulo C. Rodriguez
Paulo C. Rodriguez Moffitt Cancer Center
Andrew V. Kossenkov
Andrew V. Kossenkov The Wistar Institute
Tyler J. Curiel
Tyler J. Curiel The University of Texas at San Antonio
Gabriel A. Rabinovich
Gabriel A. Rabinovich Experimental Medicine and Biology Institute
Scott J. Antonia
Scott J. Antonia Duke University
David W. Speicher
David W. Speicher The Wistar Institute
Wayne W. Hancock
Wayne W. Hancock University of Pennsylvania

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