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Biology and Biochemistry

D-Index
64
Citations
34259
World Ranking
9432
National Ranking
4158

Overview

Ilona Kryczek is affiliated with the University of Michigan-Ann Arbor in the United States. Their research primarily focuses on immunology, oncology, molecular biology, and related biomedical fields.

The scientist's main fields of study are:

  • Immunology and Microbiology
  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these areas, their work extends into subfields including:

  • Immunology
  • Oncology
  • Molecular Biology
  • Pulmonary and Respiratory Medicine
  • Cancer Research

The major research topics covered by Ilona Kryczek include:

  • Immune Cell Function and Interaction
  • Cancer Immunotherapy and Biomarkers
  • Immunotherapy and Immune Responses
  • Immune cells in cancer
  • T-cell and B-cell Immunology
  • Epigenetics and DNA Methylation
  • Ubiquitin and proteasome pathways

Frequent publication venues that feature their work are:

  • The Journal of Immunology
  • Cancer Cell
  • Nature
  • Cancer Discovery
  • Nature Communications

Notable recent papers authored or co-authored by Ilona Kryczek include:

  • "Liver metastasis restrains immunotherapy efficacy via macrophage-mediated T cell elimination," 2021, Nature Medicine
  • "CD8+ T cells and fatty acids orchestrate tumor ferroptosis and immunity via ACSL4," 2022, Cancer Cell
  • "Cancer SLC43A2 alters T cell methionine metabolism and histone methylation," 2020, Nature
  • "LIMIT is an immunogenic lncRNA in cancer immunity and immunotherapy," 2021, Nature Cell Biology
  • "Epigenetic driver mutations in ARID1A shape cancer immune phenotype and immunotherapy," 2020, Journal of Clinical Investigation

Frequently collaborating co-authors include:

  • Weiping Zou
  • Shuang Wei
  • Linda Vatan
  • Jiali Yu
  • Arul M. Chinnaiyan

Best Publications

  • Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival.

    Tyler J Curiel;George Coukos;Linhua Zou;Xavier Alvarez

  • CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy

    Weimin Wang;Michael Green;Jae Eun Choi;Miguel Gijón

  • Fusobacterium nucleatum Promotes Chemoresistance to Colorectal Cancer by Modulating Autophagy.

    Ta Chung Yu;Fangfang Guo;Yanan Yu;Tiantian Sun

  • Epigenetic silencing of TH1-type chemokines shapes tumour immunity and immunotherapy.

    Dongjun Peng;Ilona Kryczek;Nisha Nagarsheth;Lili Zhao

  • Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments

    Ilona Kryczek;Mousumi Banerjee;Pui Cheng;Linhua Vatan

  • Radiotherapy and Immunotherapy Promote Tumoral Lipid Oxidation and Ferroptosis via Synergistic Repression of SLC7A11

    Xueting Lang;Michael D. Green;Weimin Wang;Jiali Yu

  • B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma

    Ilona Kryczek;Ilona Kryczek;Linhua Zou;Linhua Zou;Paulo Rodriguez;Gefeng Zhu

  • Liver metastasis restrains immunotherapy efficacy via macrophage-mediated T cell elimination.

    Jiali Yu;Michael D. Green;Michael D. Green;Shasha Li;Yilun Sun

  • Tumor-Associated Macrophages Produce Interleukin 6 and Signal via STAT3 to Promote Expansion of Human Hepatocellular Carcinoma Stem Cells

    Shanshan Wan;Ende Zhao;Ilona Kryczek;Linda Vatan

  • Oxidative stress controls regulatory T cell apoptosis and suppressor activity and PD-L1-blockade resistance in tumor.

    Tomasz Maj;Wei Wang;Wei Wang;Joel Crespo;Hongjuan Zhang

  • Host expression of PD-L1 determines efficacy of PD-L1 pathway blockade–mediated tumor regression

    Heng Lin;Shuang Wei;Elaine M. Hurt;Michael D. Green

  • Cutting Edge: Th17 and Regulatory T Cell Dynamics and the Regulation by IL-2 in the Tumor Microenvironment

    Ilona Kryczek;Shuang Wei;Linhua Zou;Saleh Altuwaijri

  • CXCL12 and Vascular Endothelial Growth Factor Synergistically Induce Neoangiogenesis in Human Ovarian Cancers

    Ilona Kryczek;Andrzej Lange;Peter Mottram;Xavier Alvarez

  • Induction of IL-17+ T Cell Trafficking and Development by IFN-γ: Mechanism and Pathological Relevance in Psoriasis

    Ilona Kryczek;Allen T. Bruce;Johann E. Gudjonsson;Andrew Johnston

  • Endogenous IL-17 contributes to reduced tumor growth and metastasis.

    Ilona Kryczek;Shuang Wei;Wojciech Szeliga;Linhua Vatan

  • Plasmacytoid Dendritic Cells Induce CD8+ Regulatory T Cells In Human Ovarian Carcinoma

    Shuang Wei;Ilona Kryczek;Ilona Kryczek;Linhua Zou;Ben Daniel

  • Stroma-derived factor (SDF-1/CXCL12) and human tumor pathogenesis

    Ilona Kryczek;Shuang Wei;Evan Keller;Rebecca Liu

  • Myeloid derived suppressor cells enhance stemness of cancer cells by inducing microRNA101 and suppressing the corepressor CtBP2

    Tracy X. Cui;Ilona Kryczek;Lili Zhao;Ende Zhao

  • Cancer SLC43A2 alters T cell methionine metabolism and histone methylation.

    Yingjie Bian;Wei Li;Daniel M. Kremer;Peter Sajjakulnukit

  • Relationship between B7-H4, Regulatory T Cells, and Patient Outcome in Human Ovarian Carcinoma

    Ilona Kryczek;Shuang Wei;Gefeng Zhu;Leann Myers

Frequent Co-Authors

Weiping Zou
Weiping Zou University of Michigan–Ann Arbor
Arul M. Chinnaiyan
Arul M. Chinnaiyan University of Michigan–Ann Arbor
Tyler J. Curiel
Tyler J. Curiel The University of Texas at San Antonio
Jing-Yuan Fang
Jing-Yuan Fang Shanghai Jiao Tong University
George Coukos
George Coukos Cornell University
Theodore S. Lawrence
Theodore S. Lawrence University of Michigan–Ann Arbor
Max S. Wicha
Max S. Wicha University of Michigan–Ann Arbor
Yali Dou
Yali Dou University of Southern California
Lieping Chen
Lieping Chen Yale University
Diane M. Simeone
Diane M. Simeone New York University Langone Medical Center

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