David J. Granville

Overview

Best Publications

• Endothelial cell apoptosis: biochemical characteristics and potential implications for atherosclerosis.

  Jonathan C. Choy;David J. Granville;David W.C. Hunt;Bruce M. McManus

  632
  Citations

• Allograft Vasculopathy Versus Atherosclerosis

  Maziar Rahmani;Rani P. Cruz;David J. Granville;Bruce M. McManus

  401
  Citations

• Inflammation in Myocardial Diseases

  David J. Marchant;John H. Boyd;David C. Lin;David J. Granville

  354
  Citations

• Apoptosis: molecular aspects of cell death and disease.

  D. J. Granville;C. M. Carthy;D. W. C. Hunt;B. M. Mcmanus

  339
  Citations

• Intracellular versus extracellular granzyme B in immunity and disease: challenging the dogma.

  Wendy Anne Boivin;Dawn Michelle Cooper;Dawn Michelle Cooper;Paul Ryan Hiebert;Paul Ryan Hiebert;David James Granville;David James Granville

  301
  Citations

• The Unmet Need in the Elderly: How immunosenescence, CMV infection, co-morbidities and frailty are a challenge for the development of more effective influenza vaccines

  Janet E. McElhaney;Xin Zhou;H. Keipp Talbot;Ernst Soethout

  269
  Citations

• A new transcriptional role for matrix metalloproteinase-12 in antiviral immunity

  David J Marchant;Caroline L Bellac;Theo J Moraes;Samuel J Wadsworth

  257
  Citations

• Rapid cytochrome c release, activation of caspases 3, 6, 7 and 8 followed by Bap31 cleavage in HeLa cells treated with photodynamic therapy.

  David J Granville;Chris M Carthy;Huijun Jiang;Gordon C Shore

  243
  Citations

• Caspase Activation and Specific Cleavage of Substrates after Coxsackievirus B3-Induced Cytopathic Effect in HeLa Cells

  Christopher M. Carthy;David J. Granville;Kathleen A. Watson;Daniel R. Anderson;Daniel R. Anderson

  231
  Citations

• Reduction of ischemia and reperfusion-induced myocardial damage by cytochrome P450 inhibitors

  David J. Granville;Babak Tashakkor;Cindy Takeuchi;Åsa B. Gustafsson

  200
  Citations

• Granzyme B in injury, inflammation, and repair.

  Paul R. Hiebert;David J. Granville

  179
  Citations

• Mechanism of colon cancer cell apoptosis mediated by pyropheophorbide-a methylester photosensitization

  Jean-Yves Matroule;Chris M Carthy;David J Granville;Olivier Jolois

  158
  Citations

• Moderate exercise attenuates caspase-3 activity, oxidative stress, and inhibits progression of diabetic renal disease in db/db mice.

  S. Ghosh;M. Khazaei;F. Moien-Afshari;L. S. Ang

  153
  Citations

• Bcl-2 and Bcl-xL overexpression inhibits cytochrome c release, activation of multiple caspases, and virus release following coxsackievirus B3 infection.

  Christopher M Carthy;Bobby Yanagawa;Honglin Luo;David J Granville

  150
  Citations

• Granzyme B Induces Smooth Muscle Cell Apoptosis in the Absence of Perforin Involvement of Extracellular Matrix Degradation

  Jonathan C. Choy;Vivian H.Y. Hung;Arwen L. Hunter;Paul K. Cheung

  148
  Citations

• Release of Cytochrome c, Bax Migration, Bid Cleavage, and Activation of Caspases 2, 3, 6, 7, 8, and 9 during Endothelial Cell Apoptosis

  David J. Granville;Janet R. Shaw;Simon Leong;Christopher M. Carthy

  140
  Citations

• Mitochondrial release of apoptosis-inducing factor and cytochrome c during smooth muscle cell apoptosis.

  David J. Granville;Brighid A. Cassidy;Dietrich O. Ruehlmann;Jonathan C. Choy

  136
  Citations

• Photodynamic therapy induces caspase-3 activation in HL-60 cells

  David J Granville;Julia G Levy;David Wc Hunt

  125
  Citations

• Granzyme B in atherosclerosis and transplant vascular disease: association with cell death and atherosclerotic disease severity.

  Jonathan C Choy;Paul C McDonald;Agripina C Suarez;Vivian H Y Hung

  124
  Citations

• Attenuated Acute Cardiac Rejection in NOS2 −/− Recipients Correlates With Reduced Apoptosis

  Jörg Koglin;David J. Granville;Troels Glysing-Jensen;John S. Mudgett

  119
  Citations