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Biology and Biochemistry

D-Index
78
Citations
17347
World Ranking
4642
National Ranking
111

Overview

Darryl A. Knight is affiliated with the University of Newcastle Australia in Australia. Their research primarily spans the field of Medicine, with a focus on Pulmonary and Respiratory Medicine. Additional subfields of study include Physiology, Immunology, Epidemiology, and Molecular Biology.

The scientist's work encompasses a range of topics, notably:

  • Asthma and respiratory diseases
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Neonatal Respiratory Health Research
  • IL-33, ST2, and ILC Pathways
  • Respiratory viral infections research
  • Occupational and environmental lung diseases
  • Cancer Cells and Metastasis

Frequent publication venues for their work include:

  • American Journal of Physiology-Lung Cellular and Molecular Physiology
  • Clinical Science
  • Allergy
  • European Respiratory Journal
  • Journal of Allergy and Clinical Immunology

Collaborative research is evident through regular co-authorship with several scientists, including:

  • Christopher Grainge (19 publications)
  • Andrew T. Reid (13 publications)
  • Michael Schuliga (11 publications)
  • Nathan W. Bartlett (11 publications)
  • Peter Wark (10 publications)

Some of the recent papers associated with this researcher are:

  • "Epithelial cell dysfunction, a major driver of asthma development" (2020) published in Allergy
  • "Regulation of cellular senescence by extracellular matrix during chronic fibrotic diseases" (2020) published in Clinical Science
  • "Airway Epithelial Cell Immunity Is Delayed During Rhinovirus Infection in Asthma and COPD" (2020) published in Frontiers in Immunology
  • "Plasma cell but not CD20-mediated B-cell depletion protects from bleomycin-induced lung fibrosis" (2022) published in European Respiratory Journal
  • "Assessing the unified airway hypothesis in children via transcriptional profiling of the airway epithelium" (2020) published in Journal of Allergy and Clinical Immunology

Best Publications

  • The airway epithelium: Structural and functional properties in health and disease

    Darryl A. Knight;Stephen T. Holgate;Stephen T. Holgate

  • Airway smooth muscle dynamics: A common pathway of airway obstruction in asthma

    S S An;T R Bai;J H T Bates;J L Black

  • Inhibition of Wnt/β-catenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis

    William R. Henderson;Emil Y. Chi;Xin Ye;Cu Nguyen

  • Activation of Protease-Activated Receptor (PAR)-1, PAR-2, and PAR-4 Stimulates IL-6, IL-8, and Prostaglandin E2 Release from Human Respiratory Epithelial Cells

    Nithiananthan Asokananthan;Peter T. Graham;Joshua Fink;Darryl A. Knight

  • Induction of Epithelial–Mesenchymal Transition in Primary Airway Epithelial Cells from Patients with Asthma by Transforming Growth Factor-β1

    Tillie-Louise Hackett;Stephanie Mary Warner;Dorota Stefanowicz;Furquan Shaheen

  • Role for NLRP3 Inflammasome-mediated, IL-1β-Dependent Responses in Severe, Steroid-Resistant Asthma.

    Richard Y Kim;James W Pinkerton;Ama T Essilfie;Avril A B Robertson

  • Protease-activated receptors in human airways: upregulation of PAR-2 in respiratory epithelium from patients with asthma.

    Darryl A. Knight;Sam Lim;Amelia K. Scaffidi;Nicholai Roche

  • Epithelial inducible nitric oxide synthase activity is the major determinant of nitric oxide concentration in exhaled breath

    Carly Lane;D. Knight;S. Burgess;P. Franklin

  • Structural changes in the airways in asthma: observations and consequences.

    Tony R. Bai;Darryl A. Knight

  • Airway epithelial regulation of pulmonary immune homeostasis and inflammation.

    Teal S. Hallstrand;Tillie L. Hackett;William A. Altemeier;Gustavo Matute-Bello

  • Intrinsic biochemical and functional differences in bronchial epithelial cells of children with asthma.

    Anthony Kicic;Erika N. Sutanto;Paul T. Stevens;Darryl A. Knight

  • Intrinsic phenotypic differences of asthmatic epithelium and its inflammatory responses to respiratory syncytial virus and air pollution.

    Tillie-Louise Hackett;Gurpreet K. Singhera;Furquan Shaheen;Patrick Hayden

  • Epithelial cell dysfunction, a major driver of asthma development

    Irene H. Heijink;Virinchi N. S. Kuchibhotla;Virinchi N. S. Kuchibhotla;Mirjam P. Roffel;Mirjam P. Roffel;Tania Maes

  • Inverse Effects of Interleukin-6 on Apoptosis of Fibroblasts from Pulmonary Fibrosis and Normal Lungs

    Yuben P. Moodley;Neil L. A. Misso;Amelia K. Scaffidi;Mirjana Fogel-Petrovic

  • Adenosine A3 receptor expression and function in eosinophils.

    Blair A. M. Walker;Marlene A. Jacobson;Darryl A. Knight;Christopher A. Salvatore

  • The airway epithelium nucleotide-binding domain and leucine-rich repeat protein 3 inflammasome is activated by urban particulate matter

    Jeremy A. Hirota;Simon A. Hirota;Stephanie M. Warner;Dorota Stefanowicz

  • The Processes and Mechanisms of Cardiac and Pulmonary Fibrosis

    Lucy A. Murtha;Michael J. Schuliga;Nishani S. Mabotuwana;Sean A. Hardy

  • Decreased Fibronectin Production Significantly Contributes to Dysregulated Repair of Asthmatic Epithelium

    Anthony Kicic;Teal S. Hallstrand;Erika N. Sutanto;Paul T. Stevens

  • Fibroblasts isolated from normal lungs and those with idiopathic pulmonary fibrosis differ in interleukin-6/gp130-mediated cell signaling and proliferation.

    Yuben P. Moodley;Amelia K. Scaffidi;Amelia K. Scaffidi;Neil L. Misso;Neil L. Misso;Carmel Keerthisingam

  • Genetic partitioning of interleukin-6 signalling in mice dissociates Stat3 from Smad3-mediated lung fibrosis

    Robert J.J. O'Donoghue;Darryl Andrew Knight;Carl D. Richards;Cecilia M. Prêle

Frequent Co-Authors

Philip J. Thompson
Philip J. Thompson University of Western Australia
Stephen M. Stick
Stephen M. Stick University of Western Australia
Peter A. B. Wark
Peter A. B. Wark University of Newcastle Australia
Philip M. Hansbro
Philip M. Hansbro University of Technology Sydney
Nathan W. Bartlett
Nathan W. Bartlett Imperial College London
Jay C. Horvat
Jay C. Horvat University of Newcastle Australia
Lynne Murray
Lynne Murray University of Reading
Cory M. Hogaboam
Cory M. Hogaboam Cedars-Sinai Medical Center
Teal S. Hallstrand
Teal S. Hallstrand University of Washington
Matthias Ernst
Matthias Ernst La Trobe University

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