2023 - Research.com Biology and Biochemistry in Australia Leader Award
The scientist’s investigation covers issues in Signal transduction, Immunology, Cancer research, Glycoprotein 130 and Internal medicine. His work carried out in the field of Signal transduction brings together such families of science as Receptor and Interleukin 10. Matthias Ernst interconnects Inflammation, Carcinogenesis, Tumor microenvironment and STAT3, STAT protein in the investigation of issues within Cancer research.
His work deals with themes such as Endotype and Immunotherapy, which intersect with Carcinogenesis. His Glycoprotein 130 research incorporates themes from STAT1, Molecular biology, SOCS3 and Leukemia inhibitory factor. His research in Internal medicine intersects with topics in AMP-activated protein kinase, Endocrinology and Osteoblast.
Matthias Ernst mostly deals with Cancer research, Immunology, Carcinogenesis, STAT3 and Cell biology. His Cancer research research is multidisciplinary, incorporating elements of Cancer, Colorectal cancer, Cytokine, Inflammation and Signal transduction. His Immunology research is multidisciplinary, incorporating perspectives in Lung and Mutant.
His Carcinogenesis study also includes fields such as
Matthias Ernst focuses on Cancer research, Cancer, Carcinogenesis, Tumor microenvironment and Colorectal cancer. Matthias Ernst combines subjects such as Cytokine, Cancer cell, Immune system, Immunotherapy and STAT3 with his study of Cancer research. His Cancer cell research includes elements of Tumor necrosis factor alpha and Receptor.
His Receptor study incorporates themes from Wound healing, Stromal cell and Glycoprotein 130. In general STAT3, his work in STAT protein is often linked to Drug repositioning linking many areas of study. His work deals with themes such as Wnt signaling pathway, Signal transduction, Intestinal epithelium, Macrophage polarization and Epidermis, which intersect with Carcinogenesis.
His primary scientific interests are in Cancer research, Carcinogenesis, Cancer, Wnt signaling pathway and STAT3. As a part of the same scientific study, Matthias Ernst usually deals with the Cancer research, concentrating on Immune system and frequently concerns with Stromal cell, Wound healing and STAT protein. Matthias Ernst interconnects Cytokine, Inflammation, Tumor microenvironment, Interleukin 33 and Signal transduction in the investigation of issues within Carcinogenesis.
Matthias Ernst focuses mostly in the field of Inflammation, narrowing it down to topics relating to Macrophage polarization and, in certain cases, Cytotoxic T cell. His biological study deals with issues like Colorectal cancer, which deal with fields such as Intestinal mucosa. His biological study spans a wide range of topics, including Cancer therapy, Tolerability and Bioinformatics.
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Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system.
Jason S Stumhofer;Arian Laurence;Emma H Wilson;Elaine Huang.
Nature Immunology (2006)
gp130-Mediated Stat3 Activation in Enterocytes Regulates Cell Survival and Cell-Cycle Progression during Colitis-Associated Tumorigenesis
Julia Bollrath;Toby J Phesse;Vivian A von Burstin;Tracy Putoczki.
Cancer Cell (2009)
Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10
Jason S Stumhofer;Jonathan S Silver;Arian Laurence;Paige M Porrett.
Nature Immunology (2007)
Estradiol effects on proliferation, messenger ribonucleic acid for collagen and insulin-like growth factor-I, and parathyroid hormone-stimulated adenylate cyclase activity in osteoblastic cells from calvariae and long bones.
Matthias Ernst;Joan K. Heath;Gideon A. Rodan.
Endocrinology (1989)
Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice
Niall C. Tebbutt;Andrew S. Giraud;Melissa Inglese;Brendan Jenkins.
Nature Medicine (2002)
RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis.
James A Rickard;James A Rickard;Joanne A O'Donnell;Joanne A O'Donnell;Joseph M Evans;Joseph M Evans;Najoua Lalaoui;Najoua Lalaoui.
Cell (2014)
IL-6 trans-signaling via STAT3 directs T cell infiltration in acute inflammation
Rachel Mary McLoughlin;Brendan J. Jenkins;Dianne Grail;Anwen Sian Williams.
Proceedings of the National Academy of Sciences of the United States of America (2005)
IL-6 regulates neutrophil trafficking during acute inflammation via STAT3.
Ceri Alan Fielding;Rachel Mary McLoughlin;Louise McLeod;Chantal Sophie Colmont.
Journal of Immunology (2008)
Interleukin-11 Is the Dominant IL-6 Family Cytokine during Gastrointestinal Tumorigenesis and Can Be Targeted Therapeutically
Tracy L. Putoczki;Tracy L. Putoczki;Stefan Thiem;Andrea Loving;Rita A. Busuttil;Rita A. Busuttil.
Cancer Cell (2013)
STAT3 and STAT1 mediate IL-11–dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice
Matthias Ernst;Meri Najdovska;Dianne Grail;Therese Lundgren-May.
Journal of Clinical Investigation (2008)
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