H-Index & Metrics Best Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 64 Citations 18,227 170 World Ranking 4231 National Ranking 100

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • Cytokine

The scientist’s investigation covers issues in Signal transduction, Immunology, Cancer research, Glycoprotein 130 and Internal medicine. His work carried out in the field of Signal transduction brings together such families of science as Receptor and Interleukin 10. Matthias Ernst interconnects Inflammation, Carcinogenesis, Tumor microenvironment and STAT3, STAT protein in the investigation of issues within Cancer research.

His work deals with themes such as Endotype and Immunotherapy, which intersect with Carcinogenesis. His Glycoprotein 130 research incorporates themes from STAT1, Molecular biology, SOCS3 and Leukemia inhibitory factor. His research in Internal medicine intersects with topics in AMP-activated protein kinase, Endocrinology and Osteoblast.

His most cited work include:

  • Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system. (834 citations)
  • gp130-Mediated Stat3 Activation in Enterocytes Regulates Cell Survival and Cell-Cycle Progression during Colitis-Associated Tumorigenesis (772 citations)
  • Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10 (664 citations)

What are the main themes of his work throughout his whole career to date?

Matthias Ernst mostly deals with Cancer research, Immunology, Carcinogenesis, STAT3 and Cell biology. His Cancer research research is multidisciplinary, incorporating elements of Cancer, Colorectal cancer, Cytokine, Inflammation and Signal transduction. His Immunology research is multidisciplinary, incorporating perspectives in Lung and Mutant.

His Carcinogenesis study also includes fields such as

  • Tumor microenvironment together with Immunotherapy,
  • Intestinal mucosa which intersects with area such as Inflammatory bowel disease. He usually deals with Cell biology and limits it to topics linked to Cellular differentiation and Molecular biology. His Glycoprotein 130 study deals with Receptor intersecting with Endocrinology.

He most often published in these fields:

  • Cancer research (56.85%)
  • Immunology (40.73%)
  • Carcinogenesis (31.45%)

What were the highlights of his more recent work (between 2017-2021)?

  • Cancer research (56.85%)
  • Cancer (18.15%)
  • Carcinogenesis (31.45%)

In recent papers he was focusing on the following fields of study:

Matthias Ernst focuses on Cancer research, Cancer, Carcinogenesis, Tumor microenvironment and Colorectal cancer. Matthias Ernst combines subjects such as Cytokine, Cancer cell, Immune system, Immunotherapy and STAT3 with his study of Cancer research. His Cancer cell research includes elements of Tumor necrosis factor alpha and Receptor.

His Receptor study incorporates themes from Wound healing, Stromal cell and Glycoprotein 130. In general STAT3, his work in STAT protein is often linked to Drug repositioning linking many areas of study. His work deals with themes such as Wnt signaling pathway, Signal transduction, Intestinal epithelium, Macrophage polarization and Epidermis, which intersect with Carcinogenesis.

Between 2017 and 2021, his most popular works were:

  • Targeting Macrophages in Cancer: From Bench to Bedside. (171 citations)
  • Therapeutically exploiting STAT3 activity in cancer - using tissue repair as a road map. (130 citations)
  • Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis (31 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • Cytokine

His primary scientific interests are in Cancer research, Carcinogenesis, Cancer, Wnt signaling pathway and STAT3. As a part of the same scientific study, Matthias Ernst usually deals with the Cancer research, concentrating on Immune system and frequently concerns with Stromal cell, Wound healing and STAT protein. Matthias Ernst interconnects Cytokine, Inflammation, Tumor microenvironment, Interleukin 33 and Signal transduction in the investigation of issues within Carcinogenesis.

Matthias Ernst focuses mostly in the field of Inflammation, narrowing it down to topics relating to Macrophage polarization and, in certain cases, Cytotoxic T cell. His biological study deals with issues like Colorectal cancer, which deal with fields such as Intestinal mucosa. His biological study spans a wide range of topics, including Cancer therapy, Tolerability and Bioinformatics.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system.

Jason S Stumhofer;Arian Laurence;Emma H Wilson;Elaine Huang.
Nature Immunology (2006)

1089 Citations

gp130-Mediated Stat3 Activation in Enterocytes Regulates Cell Survival and Cell-Cycle Progression during Colitis-Associated Tumorigenesis

Julia Bollrath;Toby J Phesse;Vivian A von Burstin;Tracy Putoczki.
Cancer Cell (2009)

950 Citations

Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10

Jason S Stumhofer;Jonathan S Silver;Arian Laurence;Paige M Porrett.
Nature Immunology (2007)

840 Citations

Estradiol effects on proliferation, messenger ribonucleic acid for collagen and insulin-like growth factor-I, and parathyroid hormone-stimulated adenylate cyclase activity in osteoblastic cells from calvariae and long bones.

Matthias Ernst;Joan K. Heath;Gideon A. Rodan.
Endocrinology (1989)

532 Citations

Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice

Niall C. Tebbutt;Andrew S. Giraud;Melissa Inglese;Brendan Jenkins.
Nature Medicine (2002)

496 Citations

RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis.

James A Rickard;James A Rickard;Joanne A O'Donnell;Joanne A O'Donnell;Joseph M Evans;Joseph M Evans;Najoua Lalaoui;Najoua Lalaoui.
Cell (2014)

422 Citations

STAT3 Is Required for IL-6-gp130-Dependent Activation of Hepcidin In Vivo

Antonello Pietrangelo;Uta Dierssen;Linda Valli;Cinzia Garuti.
Gastroenterology (2007)

345 Citations

IL-6 trans-signaling via STAT3 directs T cell infiltration in acute inflammation

Rachel Mary McLoughlin;Brendan J. Jenkins;Dianne Grail;Anwen Sian Williams.
Proceedings of the National Academy of Sciences of the United States of America (2005)

339 Citations

STAT3 and STAT1 mediate IL-11–dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice

Matthias Ernst;Meri Najdovska;Dianne Grail;Therese Lundgren-May.
Journal of Clinical Investigation (2008)

336 Citations

Acquiring signalling specificity from the cytokine receptor gp130

Matthias Ernst;Brendan J Jenkins.
Trends in Genetics (2004)

330 Citations

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