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Biology and Biochemistry

D-Index
78
Citations
27104
World Ranking
4477
National Ranking
114

Overview

Philippe Langella is affiliated with INRAE: Institut national de recherche pour l'agriculture, l'alimentation et l'environnement in France. Their research broadly spans biochemistry, genetics, molecular biology, and medicine, reflecting a multidisciplinary approach to the study of microbial and human health interactions.

Their primary fields of study include Biochemistry, Genetics and Molecular Biology with 78 publications, and Medicine with 70 publications. Within these domains, Langella has contributed notably to subfields such as Molecular Biology (61 publications), Food Science (35 publications), Nutrition and Dietetics (26 publications), Infectious Diseases (24 publications), and Physiology (13 publications).

Key research topics investigated by Langella emphasize the relationships between gut microbiota and health, probiotics and fermented foods, and microbial metabolites. Specific areas of focus are:

  • Gut microbiota and health
  • Probiotics and Fermented Foods
  • Clostridium difficile and Clostridium perfringens research
  • Microbial Metabolites in Food Biotechnology
  • Diet and metabolism studies
  • Infant Nutrition and Health
  • Gastrointestinal motility and disorders

Langella has frequently published in the journals Microorganisms (11 publications), bioRxiv (Cold Spring Harbor Laboratory) with 7 preprints, Gut Microbes (5 publications), Scientific Reports (5 publications), and Nutrients (4 publications).

Collaboration is an important aspect of Langella's work, with frequent coauthors including Luis G. Bermúdez-Humarán (22 coauthored works), Rebeca Martín (20), Jean-Marc Chatel (17), Florian Chain (17), and Harry Sokol (16).

Noteworthy recent papers demonstrate a diverse range of topics and publication venues:

  • Faecalibacterium: a bacterial genus with promising human health applications, 2023, FEMS Microbiology Reviews
  • Butyrate mediates anti-inflammatory effects of Faecalibacterium prausnitzii in intestinal epithelial cells through Dact3, 2020, Gut Microbes
  • Aryl hydrocarbon receptor ligand production by the gut microbiota is decreased in celiac disease leading to intestinal inflammation, 2020, Science Translational Medicine
  • The microbial metabolite p-Cresol induces autistic-like behaviors in mice by remodeling the gut microbiota, 2021, Microbiome
  • Possible Benefits of Faecalibacterium prausnitzii for Obesity-Associated Gut Disorders, 2021, Frontiers in Pharmacology

Best Publications

  • Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients

    Harry Sokol;Bénédicte Pigneur;Laurie Watterlot;Omar Lakhdari

  • Fungal microbiota dysbiosis in IBD

    Harry Sokol;Valentin Leducq;Hugues Aschard;Hang-Phuong Pham

  • Beneficial effects on host energy metabolism of short-chain fatty acids and vitamins produced by commensal and probiotic bacteria

    Jean Guy LeBlanc;Florian Chain;Rebeca Martín;Luis G. Bermúdez-Humarán

  • Identification of an anti-inflammatory protein from Faecalibacterium prausnitzii, a commensal bacterium deficient in Crohn’s disease

    E. Quévrain;M.A. Maubert;C. Michon;F. Chain;F. Chain

  • Enterococcus hirae and Barnesiella intestinihominis Facilitate Cyclophosphamide-Induced Therapeutic Immunomodulatory Effects

    Romain Daillère;Romain Daillère;Romain Daillère;Marie Vétizou;Marie Vétizou;Marie Vétizou;Nadine Waldschmitt;Takahiro Yamazaki;Takahiro Yamazaki

  • Bacteroides thetaiotaomicron and Faecalibacterium prausnitzii influence the production of mucus glycans and the development of goblet cells in the colonic epithelium of a gnotobiotic model rodent.

    Laura Wrzosek;Sylvie Miquel;Marie-Louise Noordine;Stephan Bouet;Stephan Bouet

  • Bilophila wadsworthia aggravates high fat diet induced metabolic dysfunctions in mice

    Jane M. Natividad;Bruno Lamas;Bruno Lamas;Hang Phuong Pham;Marie Laure Michel

  • Faecal microbiota study reveals specific dysbiosis in spondyloarthritis

    Maxime Breban;Julien Tap;Ariane Leboime;Roula Said-Nahal

  • Emerging Health Concepts in the Probiotics Field: Streamlining the Definitions.

    Rebeca Martín;Philippe Langella

  • Faecalibacterium prausnitzii prevents physiological damages in a chronic low-grade inflammation murine model

    Rebeca Martín;Rebeca Martín;Rebeca Martín;Sylvie Miquel;Sylvie Miquel;Florian Chain;Florian Chain;Jane M Natividad

  • The Commensal Bacterium Faecalibacterium prausnitzii Is Protective in DNBS-induced Chronic Moderate and Severe Colitis Models

    Rebeca Martín;Rebeca Martín;Rebeca Martín;Florian Chain;Florian Chain;Sylvie Miquel;Sylvie Miquel;Jun Lu

  • Identification of Metabolic Signatures Linked to Anti-Inflammatory Effects of Faecalibacterium prausnitzii

    Sylvie Miquel;Sylvie Miquel;Marion Leclerc;Marion Leclerc;Rebeca Martin;Rebeca Martin;Florian Chain;Florian Chain

  • Food-Grade Bacteria Expressing Elafin Protect Against Inflammation and Restore Colon Homeostasis

    Jean-Paul Motta;Luis G. Bermúdez-Humarán;Céline Deraison;Céline Deraison;Céline Deraison;Laurence Martin;Laurence Martin;Laurence Martin

  • Protein secretion in Lactococcus lactis : an efficient way to increase the overall heterologous protein production.

    Yves Le Loir;Vasco Azevedo;Sergio C. Oliveira;Daniela A. Freitas;Daniela A. Freitas

  • Lactobacillus rhamnosus CNCM I-3690 and the commensal bacterium Faecalibacterium prausnitzii A2-165 exhibit similar protective effects to induced barrier hyper-permeability in mice

    L Laval;R Martin;J N Natividad;F Chain

  • Faecalibacterium prausnitzii A2-165 has a high capacity to induce IL-10 in human and murine dendritic cells and modulates T cell responses

    Oriana Rossi;Lisette A. van Berkel;Florian Chain;Florian Chain;M. Tanweer Khan

  • Production and Targeting of the Brucella abortus Antigen L7/L12 in Lactococcus lactis: a First Step towards Food-Grade Live Vaccines against Brucellosis

    Luciana A. Ribeiro;Luciana A. Ribeiro;Vasco Azevedo;Yves Le Loir;Sergio C. Oliveira

  • Paradigms of Lung Microbiota Functions in Health and Disease, Particularly, in Asthma.

    Elliot Mathieu;Unai Escribano-Vazquez;Delphyne Descamps;Claire Cherbuy

  • Use of superoxide dismutase and catalase producing lactic acid bacteria in TNBS induced Crohn's disease in mice.

    Jean Guy LeBlanc;Silvina del Carmen;Anderson Miyoshi;Vasco Azevedo

  • Heterologous expression of Brucella abortus GroEL heat-shock protein in Lactococcus lactis

    Anderson Miyoshi;Luis G Bermúdez-Humarán;Luciana A Ribeiro;Yves Le Loir

Frequent Co-Authors

Luis G. Bermúdez-Humarán
Luis G. Bermúdez-Humarán University of Paris-Saclay
Harry Sokol
Harry Sokol Sorbonne University
Vasco Azevedo
Vasco Azevedo Universidade Federal de Minas Gerais
Jean Guy LeBlanc
Jean Guy LeBlanc National Scientific and Technical Research Council
Anderson Miyoshi
Anderson Miyoshi Universidade Federal de Minas Gerais
Yves Le Loir
Yves Le Loir INRAE : Institut national de recherche pour l'agriculture, l'alimentation et l'environnement
Jean-Michel Sallenave
Jean-Michel Sallenave Université Paris Cité
Nicolas Glaichenhaus
Nicolas Glaichenhaus Centre national de la recherche scientifique, CNRS
Mathias Chamaillard
Mathias Chamaillard University of Lille

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