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Nathalie Vergnolle

Nathalie Vergnolle

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Biology and Biochemistry
France
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
85
Citations
22155
World Ranking
3198
National Ranking
75

Medicine

D-Index
85
Citations
22305
World Ranking
14753
National Ranking
474

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in France Leader Award

Overview

Nathalie Vergnolle is affiliated with Inserm in France and has contributed extensively to research in medicine, with a particular focus on biochemistry, genetics, and molecular biology. Their work spans several subfields, including surgery, genetics, molecular biology, physiology, and oncology.

Their research addresses multiple topics such as gastrointestinal motility and disorders, digestive system and related health, gut microbiota and health, cancer cells and metastasis, blood coagulation and thrombosis mechanisms, inflammatory bowel disease, and coagulation, bradykinin, polyphosphates, and angioedema.

Vergnolle has been published frequently in well-regarded scientific journals. Primary publication venues include:

  • British Journal of Pharmacology
  • Gastroenterology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Reviews Gastroenterology & Hepatology
  • The Journal of Frailty & Aging

Recent papers authored or co-authored by Nathalie Vergnolle include:

  • "Planning experiments: Updated guidance on experimental design and analysis and their reporting III," 2022, British Journal of Pharmacology
  • "Gastrointestinal biofilms in health and disease," 2021, Nature Reviews Gastroenterology & Hepatology
  • "Characterization of Human Colon Organoids From Inflammatory Bowel Disease Patients," 2020, Frontiers in Cell and Developmental Biology
  • "Revisiting the Hallmarks of Aging to Identify Markers of Biological Age," 2020, The Journal of Prevention of Alzheimer s Disease
  • "S. aureus drives itch and scratch-induced skin damage through a V8 protease-PAR1 axis," 2023, Cell

The scientist has collaborated frequently with several researchers, reflecting multidisciplinary and cooperative academic interactions. Frequent co-authors include:

  • Céline Deraison
  • Jean-Paul Motta
  • Corinne Rolland
  • Étienne Buscail
  • Guillaume Le Cosquer

Best Publications

  • Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism.

    M Steinhoff;N Vergnolle;S H Young;M Tognetto

  • NSAID-induced gastric damage in rats: Requirement for inhibition of both cyclooxygenase 1 and 2

    John L. Wallace;Webb McKnight;Brian K. Reuter;Nathalie Vergnolle

  • Role for protease activity in visceral pain in irritable bowel syndrome.

    Nicolas Cenac;Christopher N. Andrews;Marinella Holzhausen;Kevin Chapman

  • Proteinase-activated receptors: transducers of proteinase-mediated signaling in inflammation and immune response.

    Martin Steinhoff;Jörg Buddenkotte;Victoria Shpacovitch;Anke Rattenholl

  • Proteinase-activated receptor-2 and hyperalgesia: A novel pain pathway.

    N. Vergnolle;N.W. Bunnett;K.A. Sharkey;V. Brussee

  • Protease-Activated Receptor 2 Sensitizes the Capsaicin Receptor Transient Receptor Potential Vanilloid Receptor 1 to Induce Hyperalgesia

    Silvia Amadesi;Jingjiang Nie;Nathalie Vergnolle;Graeme S. Cottrell

  • Protease‐activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice

    Andrew Douglas Grant;Graeme S. Cottrell;Silva Amadesi;Marcello Trevisani

  • Protease-activated receptors in inflammation, neuronal signaling and pain.

    Nathalie Vergnolle;John L Wallace;Nigel W Bunnett;Morley D Hollenberg

  • Induction of intestinal inflammation in mouse by activation of proteinase-activated receptor-2.

    Nicolas Cenac;Anne Marie Coelho;Cathy Nguyen;Steven Compton

  • The Intestinal Microenvironment and Functional Gastrointestinal Disorders

    Giovanni Barbara;Christine Feinle-Bisset;Uday C. Ghoshal;Javier Santos

  • Protease‐activated receptor 2 sensitizes TRPV1 by protein kinase Cɛ‐ and A‐dependent mechanisms in rats and mice

    Silvia Amadesi;Graeme S. Cottrell;Lorna Divino;Kevin Chapman

  • Food-Grade Bacteria Expressing Elafin Protect Against Inflammation and Restore Colon Homeostasis

    Jean-Paul Motta;Luis G. Bermúdez-Humarán;Céline Deraison;Céline Deraison;Céline Deraison;Laurence Martin;Laurence Martin;Laurence Martin

  • Proteinase-Activated Receptor-2-Activating Peptides Induce Leukocyte Rolling, Adhesion, and Extravasation In Vivo

    Nathalie Vergnolle

  • Proteinases and proteinase-activated receptor 2 : a possible role to promote visceral hyperalgesia in rats

    Anne–Marie Coelho;Nathalie Vergnolle;Bruno Guiard;Jean Fioramonti

  • Characterization of the inflammatory response to proteinase-activated receptor-2 (PAR2)-activating peptides in the rat paw.

    Nathalie Vergnolle;Morley D Hollenberg;Keith A Sharkey;John L Wallace

  • Protease inhibition as new therapeutic strategy for GI diseases

    Nathalie Vergnolle

  • Proteinase-activated receptor 2 is an anti-inflammatory signal for colonic lamina propria lymphocytes in a mouse model of colitis

    Stefano Fiorucci;Andrea Mencarelli;Barbara Palazzetti;Eleonora Distrutti

  • Characterization of Thrombin-Induced Leukocyte Rolling and Adherence: A Potential Proinflammatory Role for Proteinase-Activated Receptor-4

    Nathalie Vergnolle;Claudia K. Derian;Michael R. D’Andrea;Martin Steinhoff

  • Clinical relevance of proteinase activated receptors (pars) in the gut.

    N Vergnolle

  • A major role for proteolytic activity and proteinase-activated receptor-2 in the pathogenesis of infectious colitis

    Kristina K. Hansen;Philip M. Sherman;Laurie Cellars;Patricia Andrade-Gordon

Frequent Co-Authors

Morley D. Hollenberg
Morley D. Hollenberg University of Calgary
John L. Wallace
John L. Wallace University of Calgary
Martin Steinhoff
Martin Steinhoff Hamad Medical Corporation
Nigel W. Bunnett
Nigel W. Bunnett New York University
Laurent Alric
Laurent Alric Federal University of Toulouse Midi-Pyrénées
Philippe Langella
Philippe Langella University of Paris-Saclay
Lionel Bueno
Lionel Bueno INRAE : Institut national de recherche pour l'agriculture, l'alimentation et l'environnement
Michel Neunlist
Michel Neunlist University of Nantes
Giovanni Barbara
Giovanni Barbara University of Bologna
Roland S. Liblau
Roland S. Liblau Federal University of Toulouse Midi-Pyrénées

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