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Stefano Fiorucci

Stefano Fiorucci

D-Index & Metrics

Medicine

D-Index
91
Citations
30536
World Ranking
11747
National Ranking
438

Overview

Stefano Fiorucci is affiliated with the University of Perugia in Italy and has contributed extensively to the field of medicine, with a particular focus on subfields including oncology, surgery, epidemiology, hepatology, and molecular biology.

Their research spans numerous topics, including drug transport and resistance mechanisms, liver disease diagnosis and treatment, liver diseases and immunity, Helicobacter pylori-related gastroenterology studies, pediatric hepatobiliary diseases and treatments, gut microbiota and health, as well as SARS-CoV-2 and COVID-19 research.

Frequent coauthors collaborating with Stefano Fiorucci include Michele Biagioli, Angela Zampella, Eleonora Distrutti, Silvia Marchianò, and Cristina Di Giorgio.

Their work has been published in multiple notable venues, such as:

  • Gastroenterology
  • Recent Advances in Inflammation & Allergy Drug Discovery
  • Biochemical Pharmacology
  • Cells
  • bioRxiv (Cold Spring Harbor Laboratory)

Selected recent papers authored or co-authored by Stefano Fiorucci are:

  • Bile acids and their receptors in metabolic disorders, 2021, Progress in Lipid Research
  • Bile Acid Signaling in Inflammatory Bowel Diseases, 2020, Digestive Diseases and Sciences
  • Bile acid modulators for the treatment of nonalcoholic steatohepatitis (NASH), 2020, Expert Opinion on Investigational Drugs

Other notable publications related to topics associated with their research include:

  • Hijacking SARS-CoV-2/ACE2 Receptor Interaction by Natural and Semi-synthetic Steroidal Agents Acting on Functional Pockets on the Receptor Binding Domain, 2020, Frontiers in Chemistry
  • Bile Acids Activated Receptors in Inflammatory Bowel Disease, 2021, Cells

Best Publications

  • Hydrogen sulfide is an endogenous modulator of leukocyte-mediated inflammation

    Renata C. O. Zanardo;Vincenzo Brancaleone;Eleonora Distrutti;Stefano Fiorucci

  • 6α-Ethyl-Chenodeoxycholic Acid (6-ECDCA), a Potent and Selective FXR Agonist Endowed with Anticholestatic Activity

    Roberto Pellicciari;Stefano Fiorucci;Emidio Camaioni;Carlo Clerici

  • The third gas: H2S regulates perfusion pressure in both the isolated and perfused normal rat liver and in cirrhosis

    Stefano Fiorucci;Elisabetta Antonelli;Andrea Mencarelli;Stefano Orlandi

  • The Bile Acid Receptor FXR Is a Modulator of Intestinal Innate Immunity

    Piero Vavassori;Andrea Mencarelli;Barbara Renga;Eleonora Distrutti

  • Inhibition of Hydrogen Sulfide Generation Contributes to Gastric Injury Caused by Anti-Inflammatory Nonsteroidal Drugs

    Stefano Fiorucci;Elisabetta Antonelli;Eleonora Distrutti;Giovanni Rizzo

  • The nuclear receptor SHP mediates inhibition of hepatic stellate cells by FXR and protects against liver fibrosis

    Stefano Fiorucci;Elisabetta Antonelli;Giovanni Rizzo;Barbara Renga

  • The Emerging Roles of Hydrogen Sulfide in the Gastrointestinal Tract and Liver

    Stefano Fiorucci;Eleonora Distrutti;Giuseppe Cirino;John L. Wallace

  • FXR activation reverses insulin resistance and lipid abnormalities and protects against liver steatosis in Zucker (fa/fa) obese rats

    Sabrina Cipriani;Andrea Mencarelli;Giuseppe Palladino;Stefano Fiorucci

  • Bile Acid-Activated Receptors, Intestinal Microbiota, and the Treatment of Metabolic Disorders

    Stefano Fiorucci;Eleonora Distrutti

  • Bile Acids Activated Receptors Regulate Innate Immunity.

    Stefano Fiorucci;Michele Biagioli;Angela Zampella;Eleonora Distrutti

  • Dual inhibitors of cyclooxygenase and 5-lipoxygenase. A new avenue in anti-inflammatory therapy?

    Stefano Fiorucci;Rosaria Meli;Mariarosaria Bucci;Giuseppe Cirino

  • The Bile Acid Receptor GPBAR-1 (TGR5) Modulates Integrity of Intestinal Barrier and Immune Response to Experimental Colitis

    Sabrina Cipriani;Andrea Mencarelli;Maria Giovanna Chini;Eleonora Distrutti

  • Bile-acid-activated receptors: targeting TGR5 and farnesoid-X-receptor in lipid and glucose disorders

    Stefano Fiorucci;Andrea Mencarelli;Giuseppe Palladino;Sabrina Cipriani

  • Gut microbiota role in irritable bowel syndrome: New therapeutic strategies

    Eleonora Distrutti;Lorenzo Monaldi;Patrizia Ricci;Stefano Fiorucci

  • Gastrointestinal safety and anti-inflammatory effects of a hydrogen sulfide-releasing diclofenac derivative in the rat.

    John L. Wallace;Giuseppe Caliendo;Vincenzo Santagada;Giuseppe Cirino

  • Evidence That Hydrogen Sulfide Exerts Antinociceptive Effects in the Gastrointestinal Tract by Activating KATP Channels

    Eleonora Distrutti;Luca Sediari;Andrea Mencarelli;Barbara Renga

  • Galectin-1 suppresses experimental colitis in mice.

    Luca Santucci;Stefano Fiorucci;Natalia Rubinstein;Andrea Mencarelli

  • Bile Acid Derivatives as Ligands of the Farnesoid X Receptor. Synthesis, Evaluation, and Structure−Activity Relationship of a Series of Body and Side Chain Modified Analogues of Chenodeoxycholic Acid

    Roberto Pellicciari;Gabriele Costantino;Emidio Camaioni;Bahman M. Sadeghpour

  • Gastrointestinal Safety of NO-Aspirin (NCX-4016) in Healthy Human Volunteers:A Proof of Concept Endoscopic Study

    Stefano Fiorucci;Luca Santucci;Paolo Gresele;Roberto Maffei Faccino

  • Protective effects of 6-ethyl chenodeoxycholic acid, a farnesoid x receptor ligand, in estrogen-induced cholestasis

    Stefano Fiorucci;Carlo Clerici;Elisabetta Antonelli;Stefano Orlandi

Frequent Co-Authors

Antonio Morelli
Antonio Morelli University of Perugia
Giuseppe Cirino
Giuseppe Cirino University of Naples Federico II
John L. Wallace
John L. Wallace University of Calgary
Maria Chiara Monti
Maria Chiara Monti University of Salerno
Giuseppe Bifulco
Giuseppe Bifulco University of Salerno
Roberto Pellicciari
Roberto Pellicciari University of Perugia
Roberto Gerli
Roberto Gerli University of Perugia
Ettore Novellino
Ettore Novellino University of Naples Federico II
Morley D. Hollenberg
Morley D. Hollenberg University of Calgary

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