What is he best known for?
The fields of study he is best known for:
- Enzyme
- Organic chemistry
- Gene
Roberto Pellicciari mostly deals with Biochemistry, Internal medicine, Kynurenic acid, Endocrinology and Pharmacology.
His Biochemistry study frequently draws parallels with other fields, such as Cell biology.
In his study, which falls under the umbrella issue of Internal medicine, Bile acid, Small heterodimer partner, Retinoid X receptor and Adipogenesis is strongly linked to Farnesoid X receptor.
His Bile acid study frequently links to other fields, such as Stereochemistry.
The concepts of his Kynurenic acid study are interwoven with issues in Quinolinic acid, Kynurenine pathway, Kynurenine and Indoleamine 2,3-dioxygenase.
His Pharmacology study combines topics from a wide range of disciplines, such as Glutamate receptor, Metabotropic glutamate receptor 1 and Metabotropic glutamate receptor.
His most cited work include:
- TGR5-Mediated Bile Acid Sensing Controls Glucose Homeostasis (1079 citations)
- Targeting bile-acid signalling for metabolic diseases (796 citations)
- Manipulation of Brain Kynurenines: Glial Targets, Neuronal Effects, and Clinical Opportunities (450 citations)
What are the main themes of his work throughout his whole career to date?
His main research concerns Stereochemistry, Biochemistry, Organic chemistry, Bile acid and Metabotropic glutamate receptor.
Roberto Pellicciari has included themes like Agonist, Glycine, NMDA receptor and Chemical synthesis in his Stereochemistry study.
In general Bile acid, his work in G protein-coupled bile acid receptor is often linked to Side chain linking many areas of study.
His Metabotropic glutamate receptor research is multidisciplinary, incorporating elements of Antagonist and Metabotropic receptor.
His research investigates the connection with Kynurenic acid and areas like Quinolinic acid which intersect with concerns in Kynurenine.
His Farnesoid X receptor study combines topics in areas such as Internal medicine and Chenodeoxycholic acid.
He most often published in these fields:
- Stereochemistry (30.71%)
- Biochemistry (21.57%)
- Organic chemistry (13.20%)
What were the highlights of his more recent work (between 2010-2021)?
- Biochemistry (21.57%)
- Bile acid (13.20%)
- Receptor (10.91%)
In recent papers he was focusing on the following fields of study:
Roberto Pellicciari focuses on Biochemistry, Bile acid, Receptor, Stereochemistry and Farnesoid X receptor.
His Biochemistry study frequently draws connections between adjacent fields such as In vivo.
Roberto Pellicciari focuses mostly in the field of Bile acid, narrowing it down to topics relating to Cholestasis and, in certain cases, Metabolism.
Many of his studies on Stereochemistry involve topics that are commonly interrelated, such as Structure–activity relationship.
His Farnesoid X receptor research is multidisciplinary, incorporating perspectives in Chenodeoxycholic acid, Ligand, Transactivation, Biological activity and Allosteric regulation.
His work deals with themes such as Combinatorial chemistry and Signal transduction, Cell biology, which intersect with G protein-coupled bile acid receptor.
Between 2010 and 2021, his most popular works were:
- Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors (339 citations)
- TGR5 activation inhibits atherosclerosis by reducing macrophage inflammation and lipid loading. (300 citations)
- De novo NAD + synthesis enhances mitochondrial function and improves health (121 citations)
In his most recent research, the most cited papers focused on:
- Enzyme
- Organic chemistry
- Gene
His primary scientific interests are in Biochemistry, G protein-coupled bile acid receptor, Farnesoid X receptor, Stereochemistry and Receptor.
His study on G protein-coupled bile acid receptor also encompasses disciplines like
- Inflammation, which have a strong connection to PI3K/AKT/mTOR pathway, CCAAT-Enhancer-Binding Protein-beta, Adipose tissue and mTORC1,
- Signal transduction that connect with fields like Internal medicine, Proinflammatory cytokine and Macrophage,
- Immunology that intertwine with fields like Endocrinology.
His Farnesoid X receptor research incorporates elements of Virtual screening and Plasma protein binding.
His Stereochemistry research is multidisciplinary, relying on both Agonist, Potency and Transactivation.
His studies deal with areas such as Homology modeling and Site-directed mutagenesis as well as Receptor.
Chenodeoxycholic acid is the focus of his Bile acid research.
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