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Alberto Chiarugi

Alberto Chiarugi

D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
10745
World Ranking
13930
National Ranking
416

Overview

Alberto Chiarugi is affiliated with the University of Florence in Italy. Their primary research focus is within the field of Medicine, with significant contributions to Psychiatry and Mental Health, Pathology and Forensic Medicine, Neurology, Physiology, and Molecular Biology.

The main topics covered by their research include:

  • Migraine and Headache Studies
  • Trigeminal Neuralgia and Treatments
  • Psychosomatic Disorders and Their Treatments
  • Multiple Sclerosis Research Studies
  • Neuropeptides and Animal Physiology
  • Botulinum Toxin and Related Neurological Disorders
  • Cardiovascular Syncope and Autonomic Disorders

Chiarugi has published extensively in several journals, with frequent publication venues including:

  • Cephalalgia
  • CNS Drugs
  • European Journal of Neurology
  • Italian Journal of Pediatrics
  • CNS Spectrums

Recent papers authored or coauthored by Chiarugi include:

  • Long-Term Effectiveness of Three Anti-CGRP Monoclonal Antibodies in Resistant Chronic Migraine Patients Based on the MIDAS score, 2022, CNS Drugs
  • Enhanced dissolution, permeation and oral bioavailability of aripiprazole mixed micelles: In vitro and in vivo evaluation, 2020, International Journal of Pharmaceutics
  • Predictors of sustained response and effects of the discontinuation of anti-calcitonin gene related peptide antibodies and reinitiation in resistant chronic migraine, 2022, European Journal of Neurology
  • Effectiveness of anti-CGRP monoclonal antibodies on central symptoms of migraine, 2022, Cephalalgia
  • Switching anti-CGRP(R) monoclonal antibodies in multi-assessed non-responder patients and implications for ineffectiveness criteria: A retrospective cohort study, 2023, Cephalalgia

Their collaborative network features frequent coauthors, such as:

  • Francesco De Cesaris (22 publications)
  • Luigi Francesco Iannone (19 publications)
  • Daniela Buonvicino (18 publications)
  • Pierangelo Geppetti (16 publications)
  • Andrea Burgalassi (11 publications)

Best Publications

  • The NAD metabolome — a key determinant of cancer cell biology

    Alberto Chiarugi;Christian Dölle;Roberta Felici;Mathias Ziegler

  • Poly(ADP-ribose) polymerase: killer or conspirator? The ‘suicide hypothesis’ revisited

    Alberto Chiarugi

  • Delayed inflammation in rat meninges: implications for migraine pathophysiology.

    Uwe Reuter;Hayrunnisa Bolay;Inger Jansen-Olesen;Alberto Chiarugi

  • The emerging therapeutic potential of sirtuin-interacting drugs: from cell death to lifespan extension

    Marco Porcu;Alberto Chiarugi

  • BID mediates neuronal cell death after oxygen/ glucose deprivation and focal cerebral ischemia

    Nikolaus Plesnila;Sandra Zinkel;Dean A. Le;Sepideh Amin-Hanjani

  • Pharmacological inhibition of histone deacetylases by suberoylanilide hydroxamic acid specifically alters gene expression and reduces ischemic injury in the mouse brain.

    Giuseppe Faraco;Tristano Pancani;Laura Formentini;Paolo Mascagni

  • High mobility group box 1 protein is released by neural cells upon different stresses and worsens ischemic neurodegeneration in vitro and in vivo

    G. Faraco;S. Fossati;M. E. Bianchi;M. Patrone

  • Poly(ADP-ribose) polymerase-1 activity promotes NF-kappaB-driven transcription and microglial activation: implication for neurodegenerative disorders.

    Alberto Chiarugi;Michael A. Moskowitz

  • Nuclear factor-kappaB as a molecular target for migraine therapy.

    U Reuter;A Chiarugi;H Bolay;MA Moskowitz

  • Inhibition of Nicotinamide Phosphoribosyltransferase CELLULAR BIOENERGETICS REVEALS A MITOCHONDRIAL INSENSITIVE NAD POOL

    Maria Pittelli;Laura Formentini;Giuseppe Faraco;Andrea Lapucci

  • Inhibitors of kynurenine hydroxylase and kynureninase increase cerebral formation of kynurenate and have sedative and anticonvulsant activities

    R. Carpenedo;A. Chiarugi;P. Russi;G. Lombardi

  • PARP-1--a Perpetrator of Apoptotic Cell Death?

    Alberto Chiarugi;Michael A. Moskowitz

  • Opportunities for the repurposing of PARP inhibitors for the therapy of non-oncological diseases

    Nathan A Berger;Valerie C Besson;A Hamid Boulares;Alexander Bürkle

  • Modulation of the kynurenine pathway in search for new neuroprotective agents. Synthesis and preliminary evaluation of (m-nitrobenzoyl)alanine, a potent inhibitor of kynurenine-3-hydroxylase.

    Roberto Pellicciari;Benedetto Natalini;Gabriele Costantino;Mahmoud R. Mahmoud

  • Poly(ADP-ribose) polymerase inhibitors attenuate necrotic but not apoptotic neuronal death in experimental models of cerebral ischemia

    F Moroni;E Meli;F Peruginelli;A Chiarugi

  • Nuclear Poly(ADP-ribose) Polymerase-1 Rapidly Triggers Mitochondrial Dysfunction

    Giulia Cipriani;Elena Rapizzi;Alfredo Vannacci;Rosario Rizzuto

  • Synthesis and release of neurotoxic kynurenine metabolites by human monocyte-derived macrophages

    Alberto Chiarugi;Maura Calvani;Elena Meli;Elisabetta Traggiai

  • Histone deacetylase (HDAC) inhibitors reduce the glial inflammatory response in vitro and in vivo.

    Giuseppe Faraco;Maria Pittelli;Leonardo Cavone;Silvia Fossati

  • Similarities and differences in the neuronal death processes activated by 3OH-kynurenine and quinolinic acid.

    Alberto Chiarugi;Elena Meli;Flavio Moroni

  • STAT1 is Activated in Neurons after Ischemia and Contributes to Ischemic Brain Injury

    Yasushi Takagi;Jun Harada;Alberto Chiarugi;Michael A Moskowitz

Frequent Co-Authors

Flavio Moroni
Flavio Moroni University of Florence
Roberto Pellicciari
Roberto Pellicciari University of Perugia
Michael A. Moskowitz
Michael A. Moskowitz Harvard University
Francesco Blasi
Francesco Blasi University of Milan
Marina Pizzi
Marina Pizzi University of Brescia
Pierangelo Geppetti
Pierangelo Geppetti University of Florence
Massimo Mannelli
Massimo Mannelli University of Florence
Giulio C. Spagnoli
Giulio C. Spagnoli University Hospital of Basel
Michael Heberer
Michael Heberer University Hospital of Basel
Gloriano Moneti
Gloriano Moneti University of Florence

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