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Immunology

D-Index
75
Citations
16006
World Ranking
2016
National Ranking
52

Overview

Giulio C. Spagnoli is affiliated with the University Hospital of Basel in Switzerland. Their work focuses primarily on the fields of Medicine, Immunology, and Microbiology, with particular emphasis on Oncology and Immunology as leading subfields. This specialization includes contributions to Molecular Biology, Radiology, Nuclear Medicine and Imaging, and Pulmonary and Respiratory Medicine.

The main research topics addressed by Giulio C. Spagnoli encompass Cancer Immunotherapy and Biomarkers, Immune Cell Function and Interaction, and Immunotherapy and Immune Responses. Additional focal areas include Cancer Cells and Metastasis, CAR-T cell therapy research, T-cell and B-cell Immunology, and Cancer-related molecular mechanisms research.

The scientist has published extensively, with notable appearances in the following venues:

  • Cancers
  • Preprints.org
  • Nephrology Dialysis Transplantation
  • Scientific Reports
  • Cancer Immunology Research

Frequent collaborators include Giuseppe Sconocchia, Raoul A. Droeser, Benjamin Weixler, Luigi Terracciano, and Giandomenica Iezzi.

Key recent papers authored or coauthored by Giulio C. Spagnoli include:

  • Fibrosis and cancer: shared features and mechanisms suggest common targeted therapeutic approaches, 2020, Nephrology Dialysis Transplantation
  • Prognostic significance of CD8+ T-cells density in stage III colorectal cancer depends on SDF-1 expression, 2021, Scientific Reports
  • Infiltration by IL22-Producing T Cells Promotes Neutrophil Recruitment and Predicts Favorable Clinical Outcome in Human Colorectal Cancer, 2020, Cancer Immunology Research
  • Identification of TPM2 and CNN1 as Novel Prognostic Markers in Functionally Characterized Human Colon Cancer-Associated Stromal Cells, 2022, Cancers
  • Low Expression of Programmed Death 1 (PD-1), PD-1 Ligand 1 (PD-L1), and Low CD8+ T Lymphocyte Infiltration Identify a Subgroup of Patients With Gastric and Esophageal Adenocarcinoma With Severe Prognosis, 2020, Frontiers in Medicine

Best Publications

  • Clinical impact of programmed cell death ligand 1 expression in colorectal cancer.

    Raoul A. Droeser;Raoul A. Droeser;Christian Hirt;Christian Hirt;Carsten T. Viehl;Daniel M. Frey

  • Phase I study in melanoma patients of a vaccine with peptide-pulsed dendritic cells generated in vitro from CD34(+) hematopoietic progenitor cells.

    Andreas Mackensen;Birgit Herbst;Ji-Li Chen;Gabriele Köhler

  • Three‐dimensional culture of melanoma cells profoundly affects gene expression profile: A high density oligonucleotide array study

    Sourabh Ghosh;Giulio C. Spagnoli;Ivan Martin;Sabine Ploegert

  • Prognostic impact of the expression of putative cancer stem cell markers CD133, CD166, CD44s, EpCAM, and ALDH1 in colorectal cancer

    A Lugli;G Iezzi;I Hostettler;M G Muraro

  • IFN-α2a induces IP-10/CXCL10 and MIG/CXCL9 production in monocyte-derived dendritic cells and enhances their capacity to attract and stimulate CD8+ effector T cells

    Elisabetta Padovan;Giulio C. Spagnoli;Maria Ferrantini;Michael Heberer

  • Melanoma Cells Present a MAGE-3 Epitope to CD4+ Cytotoxic T Cells in Association with Histocompatibility Leukocyte Antigen DR11

    Simona Manici;Tiziana Sturniolo;Maria Adele Imro;Juergen Hammer

  • Modulation of T-Cell Activation by Malignant Melanoma Initiating Cells

    Tobias Schatton;Ute Schütte;Natasha Y. Frank;Qian Zhan

  • Involvement of the multilineage CD38 molecule in a unique pathway of cell activation and proliferation.

    A Funaro;G C Spagnoli;C M Ausiello;M Alessio

  • Gut microbiota modulate T cell trafficking into human colorectal cancer

    Eleonora Cremonesi;Valeria Governa;Jesus Francisco Glaus Garzon;Valentina Mele

  • Bone marrow mesenchymal stromal cells (BM-MSCs) from healthy donors and auto-immune disease patients reduce the proliferation of autologous- and allogeneic-stimulated lymphocytes in vitro

    Ciara Bocelli-Tyndall;L. Bracci;G. Spagnoli;A. Braccini

  • Genes encoding tumor-specific antigens are expressed in human myeloma cells

    N. Van Baren;F. Brasseur;D. Godelaine;G. Hames

  • Disseminated single tumor cells as detected by real-time quantitative polymerase chain reaction represent a prognostic factor in patients undergoing surgery for colorectal cancer.

    Ulrich Guller;Paul Zajac;Annelies Schnider;Beatrix Bösch

  • The Interplay Between Neutrophils and CD8+ T Cells Improves Survival in Human Colorectal Cancer.

    valeria governa;Emanuele Trella;Valentina Mele;Luigi Tornillo

  • Microtubule-Depolymerizing Agents Used in Antibody–Drug Conjugates Induce Antitumor Immunity by Stimulation of Dendritic Cells

    Philipp Müller;Kea Martin;Sebastian Theurich;Jens Schreiner

  • Identification and Intracellular Location of MAGE-3 Gene Product

    Thomas Kocher;Elke Schultz-Thater;Fred Gudat;Christoph Schaefer

  • NK cells and T cells cooperate during the clinical course of colorectal cancer

    Giuseppe Sconocchia;Serenella Eppenberger;Giulio C Spagnoli;Luigi Tornillo

  • Expression of the MAGE-A4 and NY-ESO-1 cancer-testis antigens in serous ovarian neoplasms.

    Evgeny Yakirevich;Edmond Sabo;Ofer Lavie;Salam Mazareb

  • Interdependence of CD3-Ti and CD2 activation pathways in human T lymphocytes.

    A. Alcover;C. Alberini;O. Acuto;L. K. Clayton

  • New dimensions in tumor immunology: what does 3D culture reveal?

    Chantal Feder-Mengus;Sourabh Ghosh;Sourabh Ghosh;Anca Reschner;Ivan Martin

  • CD8+ lymphocytes/ tumour-budding index: an independent prognostic factor representing a 'pro-/anti-tumour' approach to tumour host interaction in colorectal cancer.

    A Lugli;E Karamitopoulou;I Panayiotides;P Karakitsos

  • The pattern of cytokine gene expression in freshly excised human metastatic melanoma suggests a state of reversible anergy of tumor-infiltrating lymphocytes.

    Urs Lüscher;Luis Filgueira;Antonio Juretic;Markus Zuber

Frequent Co-Authors

Michael Heberer
Michael Heberer University Hospital of Basel
Luigi Terracciano
Luigi Terracciano University Hospital of Basel
Ivan Martin
Ivan Martin University Hospital of Basel
Inti Zlobec
Inti Zlobec University of Bern
Alessandro Lugli
Alessandro Lugli University of Bern
Soldano Ferrone
Soldano Ferrone Harvard University
Achim A. Jungbluth
Achim A. Jungbluth Memorial Sloan Kettering Cancer Center
Lukas Bubendorf
Lukas Bubendorf University Hospital of Basel
Fabio Malavasi
Fabio Malavasi University of Turin
Francesco Zorzato
Francesco Zorzato University of Ferrara

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