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Ellis L. Reinherz

Ellis L. Reinherz

D-Index & Metrics

Immunology

D-Index
132
Citations
65654
World Ranking
219
National Ranking
143

Research.com Recognitions

  • 2011 - AAI-Steinman Award for Human Immunology Research, American Association of Immunologists

Overview

Ellis L. Reinherz is affiliated with Harvard University in the United States and has made significant contributions across the fields of Medicine and Immunology and Microbiology. Their research work spans various subfields, including Immunology, Radiology, Nuclear Medicine and Imaging, Oncology, Molecular Biology, and Virology.

The primary topics of their research include T-cell and B-cell Immunology, Monoclonal and Polyclonal Antibodies Research, Immune Cell Function and Interaction, HIV Research and Treatment, CAR-T cell therapy research, Force Microscopy Techniques and Applications, and Cell Adhesion Molecules Research.

Reinherz has coauthored extensively with several researchers, with frequent collaborations involving Wonmuk Hwang, Robert J. Mallis, Matthew J. Lang, Aoi Akitsu, and Jonathan S. Duke-Cohan.

Their work has been published in multiple venues, with notable repeated contributions to the Biophysical Journal, bioRxiv (Cold Spring Harbor Laboratory), Proceedings of the National Academy of Sciences, eLife, and Nature Communications.

Recent published papers by Reinherz include:

  • Intrinsic Immunogenicity of Small Cell Lung Carcinoma Revealed by Its Cellular Plasticity, 2021, Cancer Discovery
  • The αβTCR mechanosensor exploits dynamic ectodomain allostery to optimize its ligand recognition site, 2020, Proceedings of the National Academy of Sciences
  • Pre-T cell receptors topologically sample self-ligands during thymocyte β-selection, 2021, Science
  • ALK peptide vaccination restores the immunogenicity of ALK-rearranged non-small cell lung cancer, 2023, Nature Cancer
  • Molecular design of the γδT cell receptor ectodomain encodes biologically fit ligand recognition in the absence of mechanosensing, 2021, Proceedings of the National Academy of Sciences

Reinherz was awarded the AAI-Steinman Award for Human Immunology Research by the American Association of Immunologists in 2011.

Best Publications

  • Discrete stages of human intrathymic differentiation: Analysis of normal thymocytes and leukemic lymphoblasts of T-cell lineage

    Ellis L. Reinherz;Patrick C. Kung;Gideon Goldstein;Raphael H. Levey

  • The differentiation and function of human T lymphocytes

    Ellis L. Reinherz;Stuart F. Schlossman

  • Monoclonal antibodies defining distinctive human T cell surface antigens

    Patrick C. Kung;Gideon Goldstein;Ellis L. Reinherz;Stuart F. Schlossman

  • Separation of functional subsets of human T cells by a monoclonal antibody.

    Ellis L. Reinherz;Patrick C. Kung;Gideon Goldstein;Stuart F. Schlossman

  • An alternative pathway of T-cell activation: A functional role for the 50 kd T11 sheep erythrocyte receptor protein

    Stefan C. Meuer;Rebecca E. Hussey;Marina Fabbi;David Fox

  • Leukocyte typing II

    Ellis L. Reinherz;Barton F. Haynes;Lee M. Nadler;Irwin D. Bernstein

  • Clonotypic structures involved in antigen-specific human T cell function. Relationship to the T3 molecular complex.

    Stefan C. Meuer;Kathleen A. Fitzgerald;Rebecca E. Hussey;James C. Hodgdon

  • A monoclonal antibody reactive with human peripheral blood monocytes.

    J Breard;E L Reinherz;P C Kung;G Goldstein

  • Current concepts in immunology: Regulation of the immune response--inducer and suppressor T-lymphocyte subsets in human beings.

    Ellis L. Reinherz;Stuart F. Schlossman

  • Clonal analysis of human cytotoxic T lymphocytes: T4+ and T8+ effector T cells recognize products of different major histocompatibility complex regions.

    Stefan C. Meuer;Stuart F. Schlossman;Ellis L. Reinherz

  • A monoclonal antibody reactive with the human cytotoxic/suppressor T cell subset previously defined by a heteroantiserum termed TH2.

    E L Reinherz;P C Kung;G Goldstein;S F Schlossman

  • Ia DETERMINANTS ON HUMAN T-CELL SUBSETS DEFINED BY MONOCLONAL ANTIBODY Activation Stimuli Required for Expression*

    E L Reinherz;P C Kung;J M Pesando;J Ritz

  • ATOMIC STRUCTURE OF A FRAGMENT OF HUMAN CD4 CONTAINING TWO IMMUNOGLOBULIN-LIKE DOMAINS

    Jiahuai Wang;Youwei Yan;Youwei Yan;Thomas P. J. Garrett;Thomas P. J. Garrett;Jinhuan Liu

  • Further Characterization of the Human Inducer T Cell Subset Defined by Monoclonal Antibody

    Ellis L. Reinherz;Patrick C. Kung;Gideon Goldstein;Stuart F. Schlossman

  • Triggering of the T3-Ti antigen-receptor complex results in clonal T-cell proliferation through an interleukin 2-dependent autocrine pathway

    Stefan C. Meuer;Rebecca E. Hussey;Doreen A. Cantrell;James C. Hodgdon

  • Antigen recognition by human T lymphocytes is linked to surface expression of the T3 molecular complex.

    Ellis L. Reinherz;Stefan Meuer;Kathleen A. Fitzgerald;Rebecca E. Hussey

  • Evidence for the T3-associated 90K heterodimer as the T-cell antigen receptor

    Stefan C. Meuer;Oreste Acuto;Rebecca E. Hussey;James C. Hodgdon

  • A soluble CD4 protein selectively inhibits HIV replication and syncytium formation.

    Rebecca E. Hussey;Neil E. Richardson;Mark Kowalski;Nicholas R. Brown

  • A Monoclonal Antibody with Selective Reactivity with Functionally Mature Human Thymocytes and All Peripheral Human T Cells

    Ellis L. Reinherz;Patrick C. Kung;Gideon Goldstein;Stuart F. Schlossman

  • Loss of suppressor T cells in active multiple sclerosis. Analysis with monoclonal antibodies.

    Ellis L. Reinherz;Howard L. Weiner;Stephen L. Hauser;Judith A. Cohen

  • The Differentiation and Function of Human T Lymphocytes Review

    Ellis L. Reinherz;Stuart F. Schlossman

Frequent Co-Authors

Stuart F. Schlossman
Stuart F. Schlossman Harvard University
Rebecca E. Hussey
Rebecca E. Hussey Dana-Farber Cancer Institute
Gerhard Wagner
Gerhard Wagner Harvard University
Jia-huai Wang
Jia-huai Wang Harvard University
Oreste Acuto
Oreste Acuto University of Oxford
Vladimir Brusic
Vladimir Brusic University of Nottingham Ningbo China
Stefan Meuer
Stefan Meuer Heidelberg University
Jerome Ritz
Jerome Ritz Harvard University
Philippe Moingeon
Philippe Moingeon Sanofi (France)

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