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Shinji Takai

Shinji Takai

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Animal Science and Veterinary
Japan
2026

D-Index & Metrics

Animal Science and Veterinary

D-Index
73
Citations
18731
World Ranking
130
National Ranking
3

Research.com Recognitions

  • 2026 - Research.com Animal Science and Veterinary in Japan Leader Award
  • 2025 - Research.com Animal Science and Veterinary in Japan Leader Award
  • 2023 - Research.com Animal Science and Veterinary in Japan Leader Award

Overview

Shinji Takai is affiliated with Kitasato University in Japan. Their research primarily focuses on infectious diseases and the molecular biology aspects of pathogens, with a substantial number of publications addressing bacterial infections and antimicrobial resistance.

Their recent papers include studies spanning from 2020 to 2021, published in various scientific journals:

  • A novel staphylococcal enterotoxin SE02 involved in a staphylococcal food poisoning outbreak that occurred in Tokyo in 2004, 2020, Food Microbiology
  • Reinvestigation of the virulence of Rhodococcus equi isolates from patients with and without AIDS, 2020, Letters in Applied Microbiology
  • Pathogenicity and genomic features of vapN-harboring Rhodococcus equi isolated from human patients, 2021, International Journal of Medical Microbiology
  • Serological epidemiological surveillance for vapN-harboring Rhodococcus equi infection in goats, 2020, Comparative Immunology Microbiology and Infectious Diseases
  • Identification of genes required for the fitness of Rhodococcus equi during the infection of mice via signature-tagged transposon mutagenesis, 2021, Journal of Veterinary Medical Science

The frequent co-authors collaborating with Shinji Takai include:

  • Yasunori Suzuki
  • Tsutomu Kakuda
  • Yukako Sasaki
  • Hiroaki Kubota
  • Hiroshi Asakura

Their works frequently appear in the following publication venues:

  • Journal of Veterinary Medical Science
  • Letters in Applied Microbiology
  • Veterinary Microbiology
  • Journal of the Japan Veterinary Medical Association
  • Comparative Immunology Microbiology and Infectious Diseases

Shinji Takai's main fields of study are Medicine and Biochemistry, Genetics and Molecular Biology, with particular expertise in:

  • Infectious Diseases
  • Endocrinology
  • Pulmonary and Respiratory Medicine
  • Food Science
  • Biotechnology

The principal research topics Takai has contributed to include:

  • Infectious Disease Case Reports and Treatments
  • Infections and bacterial resistance
  • Biliary and Gastrointestinal Fistulas
  • Antimicrobial Resistance in Staphylococcus
  • Urologic and reproductive health conditions
  • Salmonella and Campylobacter epidemiology
  • Bacteriophages and microbial interactions

Best Publications

  • Angiotensin II type 2 receptor overexpression activates the vascular kinin system and causes vasodilation.

    Yoshiaki Tsutsumi;Hiroaki Matsubara;Hiroya Masaki;Hiroki Kurihara

  • Nox1 Is Involved in Angiotensin II–Mediated Hypertension A Study in Nox1-Deficient Mice

    Kuniharu Matsuno;Hiroyuki Yamada;Kazumi Iwata;Denan Jin

  • Bone marrow monocyte lineage cells adhere on injured endothelium in a monocyte chemoattractant protein-1-dependent manner and accelerate reendothelialization as endothelial progenitor cells

    Soichiro Fujiyama;Katsuya Amano;Kazutaka Uehira;Masayuki Yoshida

  • Caspase 1–independent activation of interleukin-1β in neutrophil-predominant inflammation

    Monica Guma;Lisa Ronacher;Ru Liu-Bryan;Shinji Takai

  • Epidemiology of Rhodococcus equi infections: a review.

    Shinji Takai

  • Association between a large plasmid and 15- to 17-kilodalton antigens in virulent Rhodococcus equi.

    S Takai;T Sekizaki;T Ozawa;T Sugawara

  • Identification of 15- to 17-kilodalton antigens associated with virulent Rhodococcus equi.

    S Takai;K Koike;S Ohbushi;C Izumi

  • Prevalence of virulent Rhodococcus equi in isolates from soil and feces of horses from horse-breeding farms with and without endemic infections.

    S Takai;S Ohbushi;K Koike;S Tsubaki

  • Pathological roles of angiotensin II produced by mast cell chymase and the effects of chymase inhibition in animal models.

    Mizuo Miyazaki;Shinji Takai;Denan Jin;Michiko Muramatsu

  • Tissue angiotensin II generating system by angiotensin-converting enzyme and chymase.

    Mizuo Miyazaki;Shinji Takai

  • DNA Sequence and Comparison of Virulence Plasmids from Rhodococcus equi ATCC 33701 and 103

    Shinji Takai;Stephen A. Hines;Tsutomu Sekizaki;Vivian M. Nicholson

  • Virulence-associated plasmids in Rhodococcus equi.

    S Takai;Y Watanabe;T Ikeda;T Ozawa

  • Chymase-Dependent Angiotensin II Formation in Human Vascular Tissue

    Shinji Takai;Denan Jin;Masato Sakaguchi;Mizuo Miyazaki

  • Angiotensin Receptor-1 Blocker Inhibits Atherosclerotic Changes and Endothelial Disruption of the Aortic Valve in Hypercholesterolemic Rabbits

    Kumiko Arishiro;Masaaki Hoshiga;Nobuyuki Negoro;Denan Jin

  • Application of Sartwell's Model (Lognormal Distribution of Incubation Periods) to Age at Onset and Age at Death of Foals with Rhodococcus equi Pneumonia as Evidence of Perinatal Infection

    Miriam L. Horowitz;Noah D. Cohen;Shinji Takai;Teotimu Becu

  • Angiotensin II Receptor Type 1-Mediated Vascular Oxidative Stress and Proinflammatory Gene Expression in Aldosterone-Induced Hypertension: The Possible Role of Local Renin-Angiotensin System

    Yuki Hirono;Takanobu Yoshimoto;Noriko Suzuki;Toru Sugiyama

  • Induction of chymase that forms angiotensin II in the monkey atherosclerotic aorta

    Shinji Takai;Naotaka Shiota;Shigeyoshi Kobayashi;Eiko Matsumura

  • Identification of Virulence-Associated Antigens and Plasmids in Rhodococcus equi from Patients with AIDS

    Shinji Takai;Yumiko Imai;Nariaki Fukunaga;Yoshiyuki Uchida

  • Granulocyte Colony-Stimulating Factor–Mobilized Circulating c-Kit+/Flk-1+ Progenitor Cells Regenerate Endothelium and Inhibit Neointimal Hyperplasia After Vascular Injury

    Michitaka Takamiya;Mitsuhiko Okigaki;Mitsuhiko Okigaki;Denan Jin;Shinji Takai

  • A Novel Chymase Inhibitor, 4-[1-{[bis-(4-Methyl-phenyl)-methyl]-carbamoyl}-3-(2-ethoxy-benzyl)-4-oxo-azetidine-2-yloxy]-benzoic acid (BCEAB), Suppressed Cardiac Fibrosis in Cardiomyopathic Hamsters

    Shinji Takai;Denan Jin;Masato Sakaguchi;Satoru Katayama

  • Eplerenone Inhibits Atherosclerosis in Nonhuman Primates

    Shinji Takai;Denan Jin;Michiko Muramatsu;Kazuyoshi Kirimura

  • Anti‐atherosclerotic effects of an angiotensin converting enzyme inhibitor and an angiotensin II antagonist in Cynomolgus monkeys fed a high‐cholesterol diet

    Mizuo Miyazaki;Hiroshi Sakonjo;Shinji Takai

  • Increased local angiotensin II formation in aneurysmal aorta.

    Masayoshi Nishimoto;Shinji Takai;Hitoshi Fukumoto;Koutaro Tsunemi

  • Chymase Inhibition Reduces Infarction and Matrix Metalloproteinase-9 Activation and Attenuates Inflammation and Fibrosis after Acute Myocardial Ischemia/Reperfusion

    Shizu Oyamada;Cesario Bianchi;Shinji Takai;Louis M Chu

  • Local Angiotensin II-Generating System in Vascular Tissues: the Roles of Chymase

    Mizuo Miyazaki;Shinji Takai

  • Usefulness of serum mast cell-specific chymase levels for postmortem diagnosis of anaphylaxis

    Hajime Nishio;Shinji Takai;Mizuo Miyazaki;Hidekazu Horiuchi

  • Significance of Chymase-Dependent Angiotensin II–Forming Pathway in the Development of Vascular Proliferation

    Masayoshi Nishimoto;Shinji Takai;Shokei Kim;Denan Jin

  • Mast cell chymase expression and mast cell phenotypes in human rejected kidneys

    Mayumi Yamada;Mayumi Yamada;Makiko Ueda;Makiko Ueda;Takahiko Naruko;Takahiko Naruko;Shigeru Tanabe;Shigeru Tanabe

Frequent Co-Authors

Noah D. Cohen
Noah D. Cohen Texas A&M University
Haruki Okamura
Haruki Okamura Hyogo College of Medicine
John F. Prescott
John F. Prescott University of Guelph
Akio Nakane
Akio Nakane Hirosaki University
Gunnar Pejler
Gunnar Pejler Uppsala University
Ruby Pawankar
Ruby Pawankar Nippon Medical School
Robert Day
Robert Day Université de Sherbrooke
Marcelo Gottschalk
Marcelo Gottschalk University of Montreal
Chihiro Sugimoto
Chihiro Sugimoto Hokkaido University
Soichi Maruyama
Soichi Maruyama Nihon University

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