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Masatsugu Horiuchi

Masatsugu Horiuchi

D-Index & Metrics

Medicine

D-Index
90
Citations
28677
World Ranking
12233
National Ranking
362

Overview

Masatsugu Horiuchi is affiliated with Ehime University in Japan. Their research spans primarily across the fields of Medicine and Neuroscience, with notable contributions in Neurology, Cardiology and Cardiovascular Medicine, Physiology, Immunology, and Cancer Research.

The scientist's work frequently addresses key topics including:

  • Neuroinflammation and Neurodegeneration Mechanisms
  • Alzheimer's disease research and treatments
  • Neurological Disease Mechanisms and Treatments
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • MicroRNA in disease regulation
  • Genetics, Aging, and Longevity in Model Organisms
  • Renin-Angiotensin System Studies

Their recent published papers include:

  • "Deterioration of cognitive function after transient cerebral ischemia with amyloid-β infusion-possible amelioration of cognitive function by AT2 receptor activation", 2020, Journal of Neuroinflammation
  • "Angiotensin II and Amyloid-β Synergistically Induce Brain Vascular Smooth Muscle Cell Senescence", 2020, American Journal of Hypertension
  • "Double Deletion of Angiotensin II Type 2 and Mas Receptors Accelerates Aging-Related Muscle Weakness in Male Mice", 2021, Journal of the American Heart Association
  • "Timp-3 deficiency impairs cognitive function in mice", 2020, UNC Libraries

Masatsugu Horiuchi has collaborated frequently with several coauthors, including:

  • Masaki Mogi
  • Jun Iwanami
  • Li-Juan Min
  • Hui-Yu Bai
  • Bao-Shuai Shan

The scientist has published in journals such as:

  • Journal of Neuroinflammation
  • American Journal of Hypertension
  • Journal of the American Heart Association
  • UNC Libraries

Best Publications

  • The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2009)

    Toshio Ogihara;Kenjiro Kikuchi;Hiroaki Matsuoka;Toshiro Fujita

  • The Japanese Society of Hypertension guidelines for the management of hypertension (JSH 2014)

    Kazuaki Shimamoto;Katsuyuki Ando;Toshiro Fujita;Naoyuki Hasebe

  • Angiotensin II type 2 receptor mediates programmed cell death

    Takehiko Yamada;Masatsugu Horiuchi;Victor J. Dzau

  • The angiotensin II type 2 (AT2) receptor antagonizes the growth effects of the AT1 receptor: gain-of-function study using gene transfer

    Masatoshi Nakajima;Howard G. Hutchinson;Masahiko Fujinaga;Wataru Hayashida

  • A gene therapy strategy using a transcription factor decoy of the E2F binding site inhibits smooth muscle proliferation in vivo.

    R Morishita;G H Gibbons;M Horiuchi;K E Ellison

  • Recent Progress in Angiotensin II Type 2 Receptor Research in the Cardiovascular System

    Masatsugu Horiuchi;Masahiro Akishita;Victor J. Dzau

  • ATP-sensitive K+ channels in the hypothalamus are essential for the maintenance of glucose homeostasis.

    Takashi Miki;Birgit Liss;Kohtaro Minami;Tetsuya Shiuchi

  • Erratum: The Japanese Society of hypertension guidelines for the management of hypertension (Hypertension Research (2009) 32 (11-23) DOI: 10.1038/hr.2008.2)

    Toshio Ogihara;Kenjiro Kikuchi;Hiroaki Matsuoka;Toshiro Fujita

  • Vasoactive substances regulate vascular smooth muscle cell apoptosis. Countervailing influences of nitric oxide and angiotensin II.

    Matthew J. Pollman;Takehiko Yamada;Masatsugu Horiuchi;Gary H. Gibbons

  • Association of angiotensinogen gene T235 variant with increased risk of coronary heart disease

    T. Katsuya;G. Koike;M. Horiuchi;R.E. Pratt

  • Devil and angel in the renin-angiotensin system: ACE-angiotensin II-AT1 receptor axis vs. ACE2-angiotensin-(1-7)-Mas receptor axis.

    Masaru Iwai;Masatsugu Horiuchi

  • Possible inhibition of focal cerebral ischemia by angiotensin II type 2 receptor stimulation.

    Masaru Iwai;Hong Wei Liu;Rui Chen;Ayumi Ide

  • Nifedipine controlled-release 40 mg b.i.d. in Japanese patients with essential hypertension who responded insufficiently to nifedipine controlled-release 40 mg q.d.: a phase III, randomized, double-blind and parallel-group study

    Kazuaki Shimamoto;Naoyuki Hasebe;Sadayoshi Ito;Kazuomi Kario

  • The Japanese Society of Hypertension Committee for Guidelines for the Management of Hypertension

    Toshio Ogihara;Kenjiro Kikuchi;Toshiro Fujita;Jitsuo Higaki

  • Angiotensin II Type-1 Receptor Blocker Valsartan Enhances Insulin Sensitivity in Skeletal Muscles of Diabetic Mice

    Tetsuya Shiuchi;Masaru Iwai;Huan-Sheng Li;Lan Wu

  • Role of the sympathetic nervous system and insulin in enhancing glucose uptake in peripheral tissues after intrahypothalamic injection of leptin in rats.

    Mohammad Shahidul Haque;Y. Minokoshi;M. Hamai;M. Iwai

  • Roles of Angiotensin II Type 2 Receptor Stimulation Associated With Selective Angiotensin II Type 1 Receptor Blockade With Valsartan in the Improvement of Inflammation-Induced Vascular Injury

    Lan Wu;Masaru Iwai;Hironori Nakagami;Zhen Li

  • AT1 and AT2 Angiotensin Receptor Gene Expression in Human Heart Failure

    Guy A. Haywood;Lars Gullestad;Tomohiro Katsuya;Howard G. Hutchinson

  • Cognitive Deficit in Amyloid-β–Injected Mice Was Improved by Pretreatment With a Low Dose of Telmisartan Partly Because of Peroxisome Proliferator-Activated Receptor-γ Activation

    Kana Tsukuda;Masaki Mogi;Jun Iwanami;Li-Juan Min

  • Neuroprotective effects of the free radical scavenger Edaravone (MCI-186) in mice permanent focal brain ischemia

    Hideo Shichinohe;Satoshi Kuroda;Satoshi Kuroda;Hiroshi Yasuda;Hiroshi Yasuda;Tatsuya Ishikawa;Tatsuya Ishikawa

Frequent Co-Authors

Victor J. Dzau
Victor J. Dzau Duke University
Hiromi Rakugi
Hiromi Rakugi Osaka University
Ryuichi Morishita
Ryuichi Morishita Osaka University
Kazuaki Shimamoto
Kazuaki Shimamoto Sapporo Medical University
Toshio Ogihara
Toshio Ogihara Osaka University
Tsutomu Imaizumi
Tsutomu Imaizumi Kurume University
Sadayoshi Ito
Sadayoshi Ito Tohoku University
Jitsuo Higaki
Jitsuo Higaki Ehime University
Yasufumi Kaneda
Yasufumi Kaneda Osaka University
Thomas Unger
Thomas Unger Maastricht University

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