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Yasufumi Kaneda

Yasufumi Kaneda

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Genetics and Molecular Biology
Japan
2024
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Medicine
Japan
2023

D-Index & Metrics

Molecular Biology

D-Index
112
Citations
48492
World Ranking
341
National Ranking
23

Medicine

D-Index
111
Citations
43527
World Ranking
5350
National Ranking
113

Research.com Recognitions

  • 2024 - Research.com Genetics and Molecular Biology in Japan Leader Award
  • 2023 - Research.com Medicine in Japan Leader Award

Overview

Yasufumi Kaneda is affiliated with Osaka University in Japan and has contributed to research across medicine and biochemistry, genetics, and molecular biology. Their work spans multiple subfields including molecular biology, immunology, pulmonary and respiratory medicine, genetics, and oncology.

Kaneda's recent publications demonstrate a focus on immunotherapy and virus-based gene therapy approaches as well as cancer treatment strategies. Selected recent papers include:

  • Longitudinal Single-Cell Transcriptomics Reveals a Role for Serpina3n-Mediated Resolution of Inflammation in a Mouse Colitis Model, 2021, Cellular and Molecular Gastroenterology and Hepatology
  • A simple method using CRISPR-Cas9 to knock-out genes in murine cancerous cell lines, 2020, Scientific Reports
  • Intratumoral and s.c. injection of inactivated hemagglutinating virus of Japan envelope (GEN0101) in metastatic castration-resistant prostate cancer, 2020, Cancer Science
  • Design and Synthesis of 1,2-Deoxy-pyranose Derivatives of Spliceostatin A toward Prostate Cancer Treatment, 2020, ACS Medicinal Chemistry Letters
  • Intratumoral injection of hemagglutinating virus of Japan-envelope vector yielded an antitumor effect for advanced melanoma: a phase I/IIa clinical study, 2020, Cancer Immunology Immunotherapy

Frequent co-authors in Kaneda's research include:

  • Keisuke Nimura
  • Kotaro Saga
  • Koji Kitamura
  • Hidenori Inohara
  • Airi Ishibashi

Kaneda has published in several scientific venues multiple times, notably:

  • Scientific Reports
  • Cancer Science
  • Cancers
  • Lasers in Medical Science
  • Journal of Hypertension

The primary topics of Kaneda's work include:

  • Virus-based gene therapy research
  • Immunotherapy and Immune Responses
  • CAR-T cell therapy research
  • Immune cells in cancer
  • Cervical Cancer and HPV Research
  • Parkinson's Disease Mechanisms and Treatments
  • Nuclear Receptors and Signaling

Best Publications

  • Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

    Takeshi Nishikawa;Diane Edelstein;Xue Liang Du;Sho-ichi Yamagishi

  • Gene therapy inhibiting neointimal vascular lesion: In vivo transfer of endothelial cell nitric oxide synthase gene

    H. E. Von Der Leyen;G. H. Gibbons;R. Morishita;N. P. Lewis

  • In vivo transfection of cis element "decoy" against nuclear factor-kappaB binding site prevents myocardial infarction.

    Ryuichi Morishita;Toshiko Sugimoto;Motokuni Aoki;Iwao Kida

  • Leptin Induces Mitochondrial Superoxide Production and Monocyte Chemoattractant Protein-1 Expression in Aortic Endothelial Cells by Increasing Fatty Acid Oxidation via Protein Kinase A

    Sho Ichi Yamagishi;Diane Edelstein;Xue Liang Du;Yasufumi Kaneda

  • Novel Autologous Cell Therapy in Ischemic Limb Disease Through Growth Factor Secretion by Cultured Adipose Tissue–Derived Stromal Cells

    Hironori Nakagami;Kazuhisa Maeda;Ryuichi Morishita;Sota Iguchi

  • Increased expression of DNA cointroduced with nuclear protein in adult rat liver.

    Yasufumi Kaneda;Kunimitsu Iwai;Tsuyoshi Uchida;Tsuyoshi Uchida

  • Hepatocyte growth factor gene therapy of liver cirrhosis in rats.

    Takahiro Ueki;Yasufumi Kaneda;Hiroko Tsutsui;Kenji Nakanishi

  • Glomerulosclerosis induced by in vivo transfection of transforming growth factor-beta or platelet-derived growth factor gene into the rat kidney.

    Yoshitaka Isaka;Yoshihiro Fujiwara;Naohiko Ueda;Yasufumi Kaneda

  • A gene therapy strategy using a transcription factor decoy of the E2F binding site inhibits smooth muscle proliferation in vivo.

    R Morishita;G H Gibbons;M Horiuchi;K E Ellison

  • Gene therapy by skeletal muscle expression of decorin prevents fibrotic disease in rat kidney

    Yoshitaka Isaka;Douglas K. Brees;Kazuko Ikegaya;Yasufumi Kaneda

  • Single intraluminal delivery of antisense cdc2 kinase and proliferating-cell nuclear antigen oligonucleotides results in chronic inhibition of neointimal hyperplasia

    Ryuichi Morishita;Gary H. Gibbons;Kristin E. Ellison;Masatoshi Nakajima

  • Development of safe and efficient novel nonviral gene transfer using ultrasound: enhancement of transfection efficiency of naked plasmid DNA in skeletal muscle

    Y Taniyama;K Tachibana;K Hiraoka;M Aoki

  • Adipose tissue-derived stromal cells as a novel option for regenerative cell therapy.

    Hironori Nakagami;Ryuichi Morishita;Kazuhisa Maeda;Yasushi Kikuchi

  • Intimal hyperplasia after vascular injury is inhibited by antisense cdk 2 kinase oligonucleotides.

    R. Morishita;G. H. Gibbons;K. E. Ellison;M. Nakajima

  • A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf–Hirschhorn syndrome

    Keisuke Nimura;Kiyoe Ura;Hidetaka Shiratori;Masato Ikawa

  • Circulating bone marrow-derived osteoblast progenitor cells are recruited to the bone-forming site by the CXCR4/stromal cell-derived factor-1 pathway.

    Satoru Otsuru;Katsuto Tamai;Takehiko Yamazaki;Hideki Yoshikawa

  • Hemagglutinating virus of Japan (HVJ) envelope vector as a versatile gene delivery system

    Yasufumi Kaneda;Toshihiro Nakajima;Tomoyuki Nishikawa;Seiji Yamamoto

  • Endothelial Apoptosis Induced by Oxidative Stress Through Activation of NF-κB: Antiapoptotic Effect of Antioxidant Agents on Endothelial Cells

    Motokuni Aoki;Toshie Nata;Ryuichi Morishita;Hidetsugu Matsushita

  • Cell transplantation for the treatment of acute myocardial infarction using vascular endothelial growth factor-expressing skeletal myoblasts.

    Ken Suzuki;Bari Murtuza;Ryszard T. Smolenski;Ivan A. Sammut

  • Angiogenesis induced by hepatocyte growth factor in non-infarcted myocardium and infarcted myocardium: up-regulation of essential transcription factor for angiogenesis, ets.

    M Aoki;R Morishita;Y Taniyama;I Kida

Frequent Co-Authors

Ryuichi Morishita
Ryuichi Morishita Osaka University
Toshio Ogihara
Toshio Ogihara Osaka University
Motokuni Aoki
Motokuni Aoki Morinomiya University of Medical Sciences
Yoshiki Sawa
Yoshiki Sawa Osaka University
Toshikazu Nakamura
Toshikazu Nakamura Osaka University
Kunio Matsumoto
Kunio Matsumoto Kanazawa University
Victor J. Dzau
Victor J. Dzau Duke University
Kei Yamamoto
Kei Yamamoto University of Tokushima
Mitsuaki Isobe
Mitsuaki Isobe Tokyo Medical and Dental University
Hikaru Matsuda
Hikaru Matsuda Osaka University

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